from sequence information.nd it certainly by no means leads to a cure for the disease. >> not yet at least. butr. lupski has high hopes that some day dna sequencing will be able to do just that. >> i don't have a crystal ball so i cannot look into the future. let's say that i'm a lot more optimistic and hopeful than i was five or 10 years ago. that in my lifetime, we will see some major cures happening before because we understood the disease at the basic molecular level and wot trey finding the genes involved. and seeing exactly how genetic variation leads to these disease processes. >> now, we examine the rapidly developing technology behind dna sequencing, and how it may soon make its way into our everyday lives. it's all in your genes. just ask dr. richard gibbs. as director of the human genome sequencing center at baylor college of medicine in houston of dr. gis spends his days investigating the way genes impact our health. >> the fundamental concept is that genetics is a big determinant of your future. an

this wild sequence sequence happened. i do not know what is going on. the ball is loose. a player falls onto the floor. he was able to finish on the other end. this and a lockout. they lost 96-87. number 15, georgetown, has a star in the big east play. the eagles were smelling and upset. stephen get the past right there. . score n scores. they hoyas get the rhythm going. that is a beauty. net. second half. that is a look and also a basket. hoyras win 65-48. -48.s win 65 tied at 64. it is a team to win. he gets the three at the buzzer. .ason wins 67-64. uva less than 10 seconds to go. steps back. the launch is good. 62-61. no mrs.. -- no misses. time expires. they are upset. 63-61. beat thehnson -- record for receiving yards. something to celebrate in detroit. >> and the pistons win. ok. santa is taking a break from his workshop and spending time in virginia beach. he is not playing good morning! wow. want to start the day with something heart healthy and delicious? you're a talking bee... honey nut cheerios has whole grain oats that can help lower cholesterol. and it tast

well, almost. >> let me say that the whole sequence actually worked. a two-minute sequence works. when we came down to the shoot days, we made a damage limitation decision. we decided just so we had a better chance of succeeding to shoot it in two 60-second segments, and in post production we would join in the middle. it was half a second's worth of cgi on the exhaust books. between the two 60-second sequences. but you can't see it. >> one shot or two, this is a hit.

can see how something like that turned into thousands and thousands of photos here that are the sequence that make the video. we shot 2,355 photos, give or take. >> but as labor intensive as dave wallace's video is, there's much more. the shots inside those frames aren't digital, they're actual physical photographs. why bother? >> a company called click picks that does photo printing asked me to create something for them. so since they're a photo printing company, we definitely wanted to make sure we used real photos. so we sent those off to boston for click picks to print. they sent them back to me in a giant box with all these photos. >> like a well-oiled machine, they insert thousands of photos into the picture frames, while shooting the whole scene itself in stop motion, one frame at a time, for 11 hours. >> we've had great feedback so far. it's not in the millions just quite yet, but most importantly we have had the demographics that we want to be feeding back feeding back. we've had the photographers that are going to be using click picks. >> if this film was edited digitally and n

a sunni organization for sequences where the triads are the the. actual they're pushing an agenda on the population and the population rightly so which was a skunk and i think this is the coptic christian groups are threatened if the book brotherhood gets its constitution and imposing sharia law for. other groups of muslims for example should be places of worship are under attack in egypt and likely will be increasing your soul and this is probably one of the most major. here in intelligence projects of the last fifty years since the u.s. conference of forward of the muslim brotherhood to create islamic fascist regime if you want to use that term across the islamic world across the muslim world from afghanistan down through turkey into saudi arabia qatar and of course egypt. one of egypt's main opposition leaders and the former head of the arab league says mercy's regime is failing to fulfill the nation's hopes for change or deal with its major economic problems. the change that we want to the people hoped for dealing with the services education be

and they're aware of the effect of those shots in sequence, just as a musician would be aware of thelow of the notes and how they would rise and build to a climax. (climactic music playing) (banging) (machine gun firing) the people writing about films have seen far more than we have and are much more literate in terms of movies than we are. i mean, we all essentially watched cornell wilde movies. (man) we'll hear from that kid and i don't mean a postcard. (john turturro) there's a lot of joel and ethan in there. fish, fresh fish. (john turturro) they're not as much of a pill as "barton fink" is. (woman) let's get to work. it's late, morrie. not anymore, lil, it's early. we were doing a love scene with judy davis and they had written originally there wasn't all this kissing. and i don't think she ran her hand through her hair and then they wanted to do it a little bit different. and i didn't want to. i said, "listen you guys, i have to defend the writers here." and they were like oh, yeah, well, to hell with the writers. i said, it should be really like he's a virgin and everything. a

water boarding sequences are graphic. there is a step by step search that is almost clinical.of the film is taut, suspenseful and emotional. the film is unforgetable. one of the best of the year. very to give it a full bucket. and we'll see you on the aisle. >> if you had a chance to talk to the president, what would you ask him? students from schools around the bay area writing him letters sharing hopes for the future. >> the letters written to the president start out with a simple salutation. what follows are examples of a child's curiosity. like do you wear a suit every day? do you play angry birds? and questions adult woz lake to ask. >> how do you feel about romney lose something do you feel sad for him? >> the fifth graders in san francisco are participating in a program called mail to the chief that is organized by hand writing with out tears to encourage students to get interested in government. >> anything that you want to write is fine. okay? it's your letter. >> students have been interested in what's happening in their communities, and around the world and they're

((haos sequence from perry all)where, on the first another in the school dent shot- cafeteria.studentescribes &pscene/shotgunzahara kazmii parkville hs senior:"i was just veryydevastated, ecause ii was very shocking to see something like that could hhppen on the first day of school. not just the first week, but the first day."weeks later, another student brings a gun to sttmmers run elementary..r. dallas dance, baltimore co. schools superintendent:"ttere are so many incidents that happen every single day--or that aree single day-- thaa don't happen information with us."doctor dance createdd schooo safety offiie after the gun incidents, but he urged students they are the top deterreet to violeece.dr. dallas dance, baltimore co. schools superrntenddnt:"if see it, you're responsible. orr if it's happeniig to you, you're responsible."ssudents say that's not always easy. zahara kkzmi, parkville hs pennor:"because if they do choose to go, a lot off students will point them out, like, 'oh, you ratted me out.; or, like, 'you told on me.' so, a lot of students get scared from being bullled."a

dredging closes on november 30th and they dredged up until the end, they had very complicated dredging sequence and their dredging contracts were not approved until the end of august so they're out there and removing sand right up until the end. when we realized we had this extra, about 2400 cubic yards yards of stand that needed to be removed, we applied for a permit and we were denied, there's herring, spawning in the area and dredging is very detrimental to their spawning and habitat during this time of the year, so there's a section of sand there that's left, but we have to come back next year anyway and we're already taking steps to try to get an early dredge approval and get our contract in place so they can come in as early as april, take out that sand as well as taking out any additional sand that accumulates between now and then for a long-term. . inger there's another piece to this where floating break water, once the floating break water is installed, that that will relieve some of the treasure from the sand coming in. is that -- >> we have modeling that shows sand transportation pat

when the genome was first sequenced back in 2003 it cost $2.7 billion to do it.cing is down to $7500 per person. >> not exactly affordable. >> exactly. but we do also have commercial tests, 23 and me, for $99 can test for 200 different traits. the problem is as we were saying before we went on some of those traits are whether you have dry or wet ear wax. well, you can use a q-tip for that. >> i know children, not people, who do not want to know if, in fact, there are certain diseases that they have a genetic predisposition to. >> right. >> like alts. >> like alzheimer's. the reason is, with a lot of these diseases there are either no interventions or minimal interventions. it is true. if you knew that you had a predisposition to huntington's, say, or als, there is nothing you can do about that except die in as little discomfort as possible. do you want that shadow happening over you until you're 50 and the disease finally hits or wouldn't you rather live a full, happy life and then at 50 learn its truth? >> on the break going to you we took a shot of you and two

you showed me a machine that now sequences dna, it's the side of a large refrigerator.ow more powerful than, much more powerful than a machine just five years ago? >> well, that machine in nine days a 24/7 run, one machine, could exceed the data generation of all of the machines in the united states in the year 2007. >> you also talked about how computing has become just faster, but much more sophisticated. >> we're now a third generation artificial intelligence where computers can think, they can actually think in a con tech churl way which allows us to make decisions based on vast amounts of information. game changing. >> i think we all understand, at least i think we understand as laymen, lay people, that cancer is not one thing, so you've actually identified the ten most important cancers that you believe can be overcome in the way you just describe, either through early detection, aggressive treatment, so that they will not be life threatening. give us an example of a cancer that you believe can be essentially cured. >> i need to give you just one project and a maj

to remember how he understands things in sequence, we stroll to my favorite market.sked nelson to memorize the precise order of one of the better beer selections on the upper west side of manhattan. after staring intently at the order of about 50 different brands, we throw a blindfold on him, and -- >> another pilzner. another river horse. another goose highland. >> reporter: yes. the trick is to assign an image to each brand. so for modelo, he pictures a special sexy model. how about the dirty bastard ale? >> i just thought of the rapper ol dirty bastard. >> reporter: but here's where the story goes beyond party tricks. two weeks after the memory championship and in honor of his late grandmother, this avid climber set out to conquer mount everest. acclimating in base camp for over a month, he was able to focus on his memory workouts like never before, and despite the low oxygen, the results amazed him. >> my times for memorizing a deck of cards went through the roof. since all those numbers and cards represent these images of people i know. >> reporter: after he cli

so once you start writing, do you do it in sequence? >> i do it in sequence. it's difficult enough to keep the whole novel in my head. if i started writing siano seekers to get so confused. >> the actors to shoot out of sequins. i don't now they manage it. >> you had the advantage since your stories are told against the backdrop of history that actually happened, if you do want to make sure that history is brilliant. >> faq, so that's part of the reason for the research, but also as a kind of backup, would have written the first draft, i hired historians, best i can find them may have they read the first draft and look for mistakes and i paid them and i paid him quite well because i want them to take it seriously. major academic historian is not that expensive, but still. i want them to take a week to read my but carefully and to check facts because they don't have all the information in their head. what that means won a writing the first draft i can be a little bit free if there's some information i can find. i can make a dress out of 10 feel confident that i

you had a whole sequence of sort of radical conservatives. also, obviously, the beginnings of the religious right in the south. this was not a traditional conservatism. and so there is my post- conservatism argument. >> >> that was more the politics of the rich and poor. at the time, you were really seeing what was an early stage build up when i wrote "the politics of rich and poor," which was then a major buildup. it went on to be what we finally saw break apart in 2008. >> we talked about richard nixon. but before that, would you think of lyndon johnson? >> -- what do you think of lyndon johnson? >> i was never a fan of lyndon johnson. i don't think that his legacy is terrific. he was obviously a very capable man. in the number of ways, he was like nixon. he was suspicious of everybody. he will not be remembered as what he would like to be remembered as. obviously, he was capable and did some things as nixon did some things. johnson -- there will not put up a statue of lyndon johnson next to washington for jefferson. >> the legacy of gerald

. >> he shot this sequence in southern miami. out to film some pythons that farmers were complaining about, but instead of the python, he captured these two. you see the cotton mouth above the rattlesnake below, and the fight is on. >> it's a wrap. >> that was a neck shot right off the bat. >> i picked wisely, it looks like. >> wow, he's going to eat the snake. >> oh, yeah, the cotton mouth injects the rattlesnake with venom. the head swells, and before you know it, he starts munching. snake on snake action here. cannibalism, right? cotton mouth are known to be opportunistic eaters. took about 45 minutes before it finished its meal. while the rattlesnake was halfway into the belly, it was still rattling. >> what? >> the end of the video you see him sitting there kind of fat and happy. he looks a little girthier than prior rattlesnake meal. >>> something was caught on camera that we don't often experience. i'm going to call this video "gorillas in the wind." >> "gorillas in the wind." >> this is in rwanda. that's a female. not som

the sequence of events going back to august. key of the brotherhood had been unpopular up until he got rid of and then was off and running. so why not? he was being praised high and low for the editorial page of "the new york times" "new york times," wherever in egypt clearly distinguished in this diplomatic process in gaza against expert patients. people had come back to cairo. so it seemed to me that once again there was a tremendous opportunity. but this is something they have been looking forward to doing for quite some time. >> i agree with a lot of what steve said. arista points. one of which on the time and it may be the signals we found had something to do with that. morsi was receiving and the gaza ceasefire in the following morning catalase a crisis that we're still talking about and dealing with. i tend to look at politics in the middle east is driven primarily by domestic factors. i think it's important to note that morsi in the muslim birthrate expected the assembly, which of course the muslim brotherhood, which the

you had a whole sequence of radical conservatives also the beginnings of the religious right in the south. this was not a traditional conservatism. >> april of 2003, wealth and democracy, political history of american rich. >> that was more the politics of rich and poor but with a whole lot of detail. at that time you were really seeing what had been an early stage buildup. it was now a major buildup. it went on to be what we finally saw break apart in 2008. >> we talked about richard nixon. before him, what did you think of lyndon johnson and what is his legacy? >> i was never a fan of lyndon johnson. i don't think his legacy is terrific. he was obviously a very capable man. in a number of ways, he was like nixon. he was suspicious of everybody. he is not going to be remembered as what he would like to be remembered as. obviously, he was capable in doing something, as nixon did some things. -they'rethink johnson - not going to put up a statue of lyndon johnson next to washington. " the legacy of gerald ford? >> ford was a likable guy who was not one of the world's great talents. i always

everyone is meant to relax before they begin sequences. >> it is good for the body. i find that it gives structure to everyday life. >> one in three germans suffers from constant stress. the pace of life is continually increasing, and many have difficulty finding time to unwind, so for a lot of people, you get seems like a perfect antidote. some 5 million germans practice yoga, and some 20,000 have completed training as yoga instructors. and those numbers are increasing. the yogurt business is huge. -- the yoga business is huge. there are many different styles of yoga, but this one is the hottest trend at the moment -- quite literally. practitioners do their exercises in a room he did to nearly 41 degrees celsius. the practice comes from the united states, and adherence -- adherents really work up a sweat. there is no meditation, no enlightenment. practitioners are simply to be fit and healthy. the best should take care of itself. >> the fact that you have to concentrate on even being able to carry out depots automatically means that you have to shut off your mind. y

negotiating their own future results outside interference with managed to agree on this on this sequence stop fighting the point and to look at doris. let them negotiate become position of the transitional governing or this organ institutions should prepare for elections and should draft a new constitution. and we say fight this is consensus let's let's stick to it let's send this message very strongly. in sync and to all of those who are fate worse than france who just signed this document said no this is not enough we have to have a security council chapter seven resolution and we have to have some addition to this scheme saying that asset is out but this is not what the agreed so. our tradition is when we negotiate something and when when we agree on something we respect the agreement unfortunately those of our partners who negotiated with us in geneva probably have different habits and we still feel that the negative effect of this. so. the geneva scheme is absolutely. actual today. who was appointed to replace kofi annan and read the rate that it is the basis for his activities we a

lot of reporting, the screenwriter did to kind of suss out the facts but in terms of the torture sequence, were they right that waterboarding led to the information that led to bin laden? >> not according to the senate intelligence committee. the film is a great film and it covers a lot of themes about the war on terror and the decade-long struggle against al qaeda. and i mean, as a sort of overall picture, there's a lot of things that are good about the film. but the fact that is senate intelligence committee which has spent three years investigating the claim that coercive interrogation techniques led to bin laden amongst other claims found that there was no, basically no truth to that. they haven't released their official report yet, but the heads of the committee have publicly stated this several months ago. >> in the film, the first 20 or 30 minutes, probably 20 minutes, is a rather extended interrogation sequence and some of the techniques are -- would be classified as torture, i guess. it's an arguable point, but waterboarding used to be classified as torture when the khmer rouge d

after this sequence is over, can't wait to get his thoughts on these two teams going at it. >> gus: outf bounds. 7:32 to play in the fourth. this is what they're playing for, and more. the big ten conference championship trophy. ladies, why's your man watching this snoozer of a game? because i'm on his fantasy football team. so he gets pretend points if we win or not! it's a guy thing. like dr pepper ten. with all 23 flavors in just ten manly calories, it's like a fantasy soda. but you can drink it. get in there hot dog! it's what guys want... ...like scoring touchdowns with players they're fake-coaching. whew, so close. so keep the "reality" tv and lady drinks. we're good. dr pepper ten. it's not for women. anyou can do anythinge latest with those gifts. where does santa claus live? (siri beeps): okay. here you go. hey, maybe try him on facetime. (facetime rings) vo: all things apple. all at your local best buy. [ male announcer ] lifts to clear obstacles. ♪ lowers to cut drag. rises to every challenge. the class exclusive air suspension in the new 2013 ram 1500. engineered to move hea

. >> reporter: the horrifying sequence begins friday morning, they don't know what time. when adam lanza takes hundreds of rounds of ammunition and four firearms from his gun enthusiast mother and shooting her while she lay sleeping. before leaving he damages his computers. just before 9:30 he loads the guns and ammunition into his mother's car and drives the roughly five miles to sandy hook elementary school, a place he knows from his childhood, officials say. >> he had a relationship to the school. had attended there, at least that's what i'm led to believe. but, beyond that, we really don't know a whole lot. >> reporter: relatives say his mother once volunteered there, but apparently there's no record of that. he's carrying two handguns and a bush master ar-15-style rifle. the school door is locked state officials say, so adam lanza blasts his way in with a rifle shattering a window. the sound alerts principal dawn hochsprung and school cyclingist mary sherlach. he turns left toward the kindergarten and first class and he heads to the classroom of substitute teacher la

who will carry out the sequencing and analysis over the next five years has not been worked out, buthe prime minister on a visit to cambridge said the project has the potential to transform cancer treatment. >> the dna database can help us to do that, but we also want to keep britain at the forefront of biotechnology, pharmaceutical industry. we can be a world leader. >> at the heart of each human cell is a bundle of tightly packed dna lounge in the spiral shaped of the double helix. there are 3 billion pairs of chemical code. by comparing mutations in the cancer cells of thousands of patients, scientists will be able to look for patterns and find out why some patients respond to treatment better than others. it should mean more targeted therapy and help in the hunt for new treatments. >> we know from the bar code in your cancer that he will respond to this treatment, but not to this treatment. that is sherry important. we have treatment that works for some -- that is very important. we have treatment that works for some of our patients. the testing is possible only because of the dr

tough sequence for the wildcats there. >> greg: this is really an example with a young team. there is so much time left, you don't need to foul there but you talked about it, goodwin showing the ability to attack the rim here in this second half, just not able to get it -- yeah, there is a little bit of contact but we've seen it on both ends. the officials are letting them determine the outcome of the game. >> clark: and i don't mind that at all. again, i thought he could are gone to the left hand because he had to shoot his back-up across his body while going away from the goal. that would have been the case where the left hand would have been ideally positioned for that finish. >> tim: louisville hit six of their last six from the line but that by blackshear was key. >> greg: the other thing from kentucky's standpoint, i think we're starting to see their identity. they are really growing up right in front of our eyes. you're seeing now, their players are getting the shots that their talent dictates. >> clark: now you don't need to rush anything. execute, get high quality sh

and i also remember a time of being held underwater when we were doing the underwater sequence.me kind of rage when your breath is held too long, you panic. but i think maria was beyond the panic moment when she-- you had given up and within. >> those situations are beyond any words we have to communicate, it was like panic what is panic. i mean that wasn't panic. >> rose: were you there while they were making the povie. >> yeah. >> rose: so you had all the-- you had every moment could talk to her. >> not the whole time but yes n the rehearsals and the preparation we had a good amount of time to speak to each other. and then they came to thailand which was a pretty big moment for you guy, wasn't it. >> uh-huh. >> and when she wasn't there, thank goodness, maria just like an open book, it just flushes out of her. and she would write these long long letters. and you know, every time we would change scenes i would read pages and pages of descriptive detail of what she was going through. >> rose: you said i think somewhere you couldn't think about your own kids when you were filming