shukla: right. the essential idea is agnostic, meaning the immune system does not make too much of a difference between, let's say, a breast cancer tissue versus a brain cancer tissue, versus leukemia, for that matter. what it cares about is what is different, right? that is what drives the immune system. if you think about an immune system, how does the immune system know that this is how we go after a cell? an otherwise healthy cell, what it is -- when it is affected by a virus, like the sars-cov-2 virus we have been dealing with, or a flu virus, for that matter, or bacteria, these raise red flags that the immune system is able to identify and launch an attack against. in cancer, the same thing happens, except it is not an external infection, at least, you know, for the non-bodily driven cancers, but essentially changes that happen within the cancer, which we call mutations come of that now raise very similar red flags that the immune system can recognize. so, in theory, the vaccine approach could