genes that come together to form sickle hemoglobin, and as you know, hemoglobin is the protein that's found in our red cells that carries oxygen to all the surrounding tissues and organs, but in individuals who carry, who have sickle-cell disease, unfortunately, during times of infection, when you're under low oxygen states, under stress, dehydration, those red cells actually take the appearance of a sickle shape and end up occluding or aclotting those vessels and oxygen and nutrients /j that area and people end up having the most common symptom of pain related to sickle-cell disease and other complications. >> reverend newton, you are a former patient. i say that, because you had circumstantial cell. you were diagnosed it five -- >> yes. >> age of 5. >> yes. >> and you -- you lived with it for most of your life, until about nine years ago. >> yes. nine years ago i received a bone marrow transplant at the john hopkins hospital in baltimore and ever since then i have been cured of sickle-cell anina. >> your whole life changed? >> it did. i went fr

three patients with sickle cell anemia and hemoglobin efficiency, phase ii trial results might be revealed in chicago december 5th through 8th. jim, i'll be looking for an attractive entry point into this stock. what are your thoughts on plume berg? >> i'm so thankful. thanks, for the kind words. i am glad you brought this up. why? this group has been slaughtered. i look at bloomberg bio, i say exactly like you did, which is at one point celgene will do what it did, it can buy the rest. not at this point. i think there is going to be pain for those who buy it. if you take a longer-term view, there is no doubt in my mind bloomberg is currently more than it's selling for. how about sally in ohio, please, sally? >> boo-yah, boo-yah, mr. cramer. >> i like that. >> caller: from columbus, ohio, home of the famous ohio state buckeyes. >> well, number one, looking good. >> looking good. you are right. i have been a long-term loyal investor with the company called atmail for several years and i would like to know if the stock is overvalued at its current p.e. is it time to buy more? or should i sel