>> skylar neese. >> the neesess world had fallen apart. their only daughter had disappeared into the night and now she'd been gone for almost 24 hours. where was skylar? >> the investigation begins, and concern for skylar begins to grow. >> coming up -- >> just had this horrible feeling in my heart that something terrible had happened. >> mary told me that night, she said something's wrong, something's bad wrong. >> a grainy piece of videotape is about to give police one giant clue. what can they glean from this? >> she slowly walked down to a car and she got in the back seat. >> when "dateline" continues. when eye allergens attack, the itch can last 24 hours. but with pataday once daily relief extra strength you get fast, 24-hour relief in one drop. make it a pataday with the drop that's right for you. now without a prescription. everywhere. these are real people, not actors, who've got their eczema under control. with less eczema, you can show more skin. so roll up those sleeves. and help heal your skin from within with dupixent. dupixent