branwenjeffreys, bbc news, staffordshire. a hug from a loved one, have won the nobel prize for medicine. david julius and ardem patapoutian used chilli to identify the sensors that enable the body to feel temperatures and pressure, which could lead to new ways of treating pain. james clayton has more details from california. the challenge that we set out to solve in the lab was to understand the molecules and signalling pathways that underlie our sense of touch. professor david julius and his team set out to better understand how we interact the world, from our morning coffee to a hug from a loved one. you might think it is pretty obvious when a cup of coffee is too hot or a drink is too cold, but scientists haven't actually understood fully how we experience those sensations, and that is why this research is deemed to be so important. not only does it improve our understanding, but it could have huge implications for how we manage pain. researchers investigated the burning sensation we feel from eating a hot chile pepper. th

brandmanjeffreys bbc news, staffordshire.charges against her. lucy letby, from hereford, worked at the countess of chester hospital betweenjune 2015 and june 2016. miss letby repeated "not guilty" to all 18 charges as she appeared via video link from prison in peterborough. her trial is due to begin in october next year. two american scientists who discovered how our bodies sense the warmth of the sun or feel the hug of a loved one have won the nobel prize for medicine. david julius and ardem patapoutian used chilli and wasabi to identify the sensors that enable the body to feel heat, pain and pressure. 0ur north america reporter james clayton reports from san francisco. we set out to understand the molecules that underlie our sense of function. ., , ,., molecules that underlie our sense of function. ., ,,., g , ., , function. professorjulius and his team set out _ function. professorjulius and his team set out to _ function. professorjulius and his team set out to better— function. professorjulius and his l team set out to b

t national memorial arboretum in staffordshire.— staffordshire.he bastian memorial wall in camp bastion in helmand province in afghanistan and there are materials from the wall in the memorial here and the names of many of those who died in that conflict and in about an hour�*s time there will be a wreath—laying ceremony and a salary will be led by the pipe major, peter grant, who i am delighted to say joins us this morning. how important is it for you to take part in the event this morning? tt�*s is it for you to take part in the event this morning? it's really important _ event this morning? it's really important and _ event this morning? it's really important and a _ event this morning? it's really important and a great - event this morning? it's really important and a great honourl event this morning? it's really - important and a great honour because i important and a great honour because i served _ important and a great honour because i served in_ important and a great honour because i served in afghanistan myself on a couple _ i served in a

we have moved to a new location in staffordshire so it is still in our milk heartland and the centralher change. i horrid effects of weather chance. .., . �* change. i can imagine. and in terms of _ change. i can imagine. and in terms of the _ change. i can imagine. and in terms of the hot _ change. i can imagine. and in terms of the hot favourite - change. i can imagine. and in| terms of the hot favourite who is going to come out the winner and from which country?- is going to come out the winner and from which country? well, i can't answer _ and from which country? well, i can't answer that _ and from which country? well, i can't answer that question - can�*t answer that question simply because i don�*t know. the competition dot—mac so we�*re going to be hit by about 250 or sojudges had 130 stewards in an hour and a half from now. they will get briefed and they were then set off to start the judging process. and they were then set off to start thejudging process. and it will get whittled down during the course of the morning to eventually about ten or 15 cheese on a table. and it co

3,000 supporters will watch them at their home ground of the bowl in douglas, where they play the staffordshire in england's football pyramid. but this is fc isle of man, who started injuly in the 10th tier of the game. but so far they've played all their matches away from home. that's meant a flight into manchester or a ferry to liverpool, with 6am starts on 12—hour round trips. on wednesday, they faced cheadle town. you pass it, then you move. but knowing soon things would change. this is fc isle of man's 14th away game in a row, but now double—jabbed passengers can travel to the island and vaccine take—up in the league has increased. so on saturday, finally they play their first match at home. i think it's brilliant, they've had to go through a lot of hoops and a lot of paperwork to get us this far and i feel very, very fortunate and privileged to be the first manager. there will be a few nerves. yeah, i naturally get nervous anyway every game but we will be in front of a crowd like that we're not used to playing in front of, so amazing for it to have happened. the club will fund the travel

commemorative services will take place in london and here at the national memorial arboretum in staffordshire big changes to travel rules kick in.

a simple, low—key ceremony at the national arboretum in staffordshire marked the start and the end of laid for those who made the ultimate sacrifice. there is an emptiness, there is a hole. 457 british military personnel lost their lives one of them was james hill, killed by an ied. he was just 23 and about to get married. his parents are proud of his service although the recent return of afghanistan to taliban control has been hard for them to bear. if we were to say now, yes, james's life was wasted, then that would hurt us all over again. one hand says, what the heck did we go there for? 0n the other hand, we stopped any terrorist atrocities and our streets. when you balance that, do you think the sacrifice that you have made of your only son has been worth it? no. nothing is worth it. that's not worth anything. many who survived still bear the physical and mental scars. luke lost both his legs a roadside bomb. sport has helped with his recovery. this summer he was due to take part in the tokyo paralympics. but because of an injury, instead he had to stay at home and witness the co

supporters will watch them at their home ground of the bowl in douglas, where they'll play the staffordshire before. a team from the isle of man's rolling hill england's football pyramid. but this is fc i'll of man who started injuly in july in the tenth year of the game. they are now nearly halfway through the season but up to now they've played all their games away from home. that's meant a flight into manchester or a ferry to liverpool. with 6am start in 12 hour round trips. on wednesday they face shield town. ., ,, y., ., town. you pass it, then you move. but knowing _ town. you pass it, then you move. but knowing soon _ town. you pass it, then you move. but knowing soon things _ town. you pass it, then you move. but knowing soon things will- town. you pass it, then you move. i but knowing soon things will change. this is fc isle of man 14th away game in a row. but now double jab passengers can travel to the island and vaccine take up in the league has increased was up so on saturday finally they play their first match at home. i finally they play their first match at home. ~ �* . finall

at dawn today, wreaths were laid at the bastion memorial in staffordshire and at the iraq and afghanistanian hill's only son, james. it never leaves us. we don't have a son anymore, we don't have any other children. there is an emptiness, there's a hole that nothing can fill. remembrance day for most people is november the 11th, but, for the likes of us, remembrance day is every day. it's nearly 12 years to the day that james hill was killed by an improvised explosive device in helmand. he was just 23 and about to get married. his parents are proud of his service and his sacrifice, though the recent return of afghanistan to taliban control has been hard for them to bear. if we were to say now, yes, james's life was wasted, then that would hurt us all over again, because we have to believe that what he did made a difference and what they all did, and that they gave so much, notjust the ones who died, but the ones who carry on with injuries. one hand says, what the heck did we go there for? the other hand says, we've stopped any terrorist atrocities on our streets. and, as claire said, anot

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