lauren streicher.l professor of obstetrics and gynecology at northwestern university's feinberg school of medicine. dr., thank you so much for joining us. in the early 2000's, there was a lot of fear that started to emerge around hormone replacement therapy's correlation with breast cancer and other diseases. can you put into context how disruptive those findings were for womens' health and how this new study fits in to our understanding of safety today? dr. streicher: what happened 22 years ago when the whi was first released was a huge deal because it was terrifying for the millions of women who had been taking hormone therapy thinking not only would relieve their menopause symptoms but that it might also help in terms of prevention of chronic diseases. and with done -- and within one day people were flushing their home own therapy down the toilet out of fear this hormone therapy that had been recommended by their doctors was going to give them breast cancer, heart disease, blood clots, and this comp