i think the f.d.a. has always tried to do the best job it could, but the opponents' gotten tough very quickly and we are having to change our tact here. we are going to do that. senator merkley: i know you were in the f.d.a. last year when the food and drug administration approved oxycontin for children without an advisory panel. it just kind of defies logic and so i want to ask the question again. why did the f.d.a. decide to do away with advisory passengers -- panels on these dangerous drugs? dr. califf: let me address the two you brought up. it will take just a minute if it's ok. i know we are pressed for time here. zohydro issue, the panel took a vote that you recited, but it also sess phied there were criteria that might make it ok. their problem was they were concerned about the post market system that was in place. and i have learned there was a feeling at the f.d.a. that the requirements of the advisory panel were met, so it was not felt that it was really disagreeing with the advisory panel. it

the f.d.a. act as an amendment to this bill. this amendment would strengthen the action that the f.d.a. recently announced that they were committed to taking into consideration the public health impact of approving opioid medications. now, mind you, what they said is that they were committed to taking into consideration. i don't think that's much of a change and it's definitely not a cultural change. it's a movement in the right direction, which i acknowledge. but by solidifying this commitment in the agency's mission statement, we ensure that the agency oversees the approval of these dangerous drugs and cannot waiver from their stated goals. the language in my amendment is similar to the language in the f.d.a.'s current mission statement regarding tobacco and we all know the devastating effects of tobacco. the mission statement says simply this, mr. president. "f.d.a. also has the responsibility for regulating the manufacturing, marketing and distribution of tobacco products to protect the publi

have the f.d.a. select a symbol to put on the package.you know, we could solve this whole debate immediately, for those who want to put on something like a q.r. code and just say, scan this code for g.e. ingredients in this product. okay. now the consumer gets the one-second test. they look at it, they see there's g.e. ingredients, that's all they want to know. they don't want to give up year privacy by scanning it. they don't want to go to the web site. there's a third idea that's been put forward, a third thing that's supposed to count as answering question inquiries. that's in this bill, to put information on social media. okay, so now this really, really adds -- this triples -- this tre size of the house of mirrors. because you go and you look at the product and you go, oh, did it have a q.r. code? well, no. did it have an 800 number? no. oh, there's a social media thing. well, we all know that there's over 100 companies doing different types of social media. we know the famous ones, we know facebook and instagram and twitter. so wher

today the f.d.a. said it's i issuing its strongest warning about essure, an implantable, permanent contraceptive device en used by three-quarters of a vi million women. some have complained of chronic c the f.d.a. ordered the manufacturer, bayer, to conduct a new safety study. it stopped short of removing the device from the market. and we will be right back. the life behind it. our nation have earned the very best service in return. usaa. we know what it means to serve. get an auto insurance quote and see why 92% of our members plan to stay for life. (rebecca) i've struggled with depression. i thought i needed cigarettes to cope. i was able to quit smoking. and then i started running. now, i feel a lot better. (announcer)you can quit. for free help, call 1-800-quit-now. good news. you're down with crestor. alright! now there's a way you can get crestor for $3. adding crestor, along with diet, crestor is not for people with liver disease, or women who are nursing,pregnant, or may become pregnant. tell

anti-abortion activists say the f.d.a. has restated that on rare occasions, the drugs can cause infection or death. americans united for life says: the new label affirms the deadly realities of chemical abortion and sundayscores the need for in-person patient examination and follow-up care. >> like in any medication you take, if you are taking it without medical supervision, you don't really know what the side effect is, what the consequences. >> the f.d.a. says more recent scientific data says it was time for an update. many doctors have been diverg diverging, prescribing off label. the f.d.a. says it has based their new guidelines on recent scientific data. the previous requirements had been in place since the year 2000. >> is there a sense that this is going to request the cost for what are called medication abortions? >> medical experts say it probably will because the medication is being reduced from 600 milligrams to 200 milligrams. and, also, because the guidelines are being easy it will probably be prescribed more o

but the f.d.a. approved the drug anyway. overruling the concerns voiced by experienceds physicians on the panel. in 2014, in the wake of the zohydro decision, the f.d.a. twice skipped the advisory committee process altogether when it approved two new prescription opioids. then in august of 2015, the f.d.a. did it again. this time it bypassed an advisory committee of outside experts on the question of a new use for oxycontin for children aged 11-16. the f.d.a. even ignored its own rules that specifically call for advisory committee advice when a question of pediatric dosing is vovmentdosing --is involved. it was quleer that the f.d.a. was intentionally choosing to forego advisory committees in order to avoid another yore whelming zohydro-like vote. recommending against approval of a prescription opioid and in order to avoid any impediments to new opioids being sold in the united states. and finally, the medical profession must bear its fair share of responsibility for this crisis. doctors are prescribing opioids at an alarmin

at the core of it is the quality system built on high level analytics so we can deploy f.d.a. forces in the most fficient and effective manner. on the human drugs and devices side we have several key priorities, include pregsigs medicine which you're well aware of. it's an amazing time in biotechnology but also the compounding issue, which we're still working on, and antibiotic, anti-microbial resistance which is a huge issue we're all facing and we want to tackle. at the core of it, for me, is that we're in a continuing evolution of the f.d.a. as a science based public health organization with a very broad scope of activities. there are an amazing array of details that we can talk about, they're specified in my testimony and what we submitted. i look forward to taking your questions. senator moran: commissioner, thank you very much. let me first of all agree with you and express my appreciation for the work by dr. ostrof at f.d.a. very much value his service to the agency and to the american people. who in my view is safer because of his work. so thank you for that service and

the f.d.a. took several steps based on sound science regarding food produced from biotech plants, including issuing final guidance from manufacturers who wish to voluntarily label their products as containing ingredients from biotech or exclusively nonbiotech plants. and more importantly, mr. president, the food and drug administration denied a petition that would have required the mandatory labeling of biotech foods. the f.d.a. stated that the petitioner failed to provide the evidence needed for the agency to put such a requirement in place because there is no health, safety or nutritional difference between biotech crops and their nonbiotech varieties. regardless of some of the rhetoric you have heard on the floor of this senate. thus it is clear that what we are facing today is not a safety or health issue, despite claims by my colleagues on the senate floor. it is a market issue. this is really about a conversation about a few states dictating to every other state the way food moves from farm

. >>> well, on health check at 11:00 the f.d.a. calling on the pharmaceutical industry to make powerful painkillers more resistant to abuse. for example, the drugs can be produced in forms that cannot be crushed or altered, and f.d.a. wants drug makers to research whether formulations they come up with actually make a difference in addiction. guidance from the f.d.a. will help drug makers to make cheaper generic versions with deterrence as well. >>> a heads up for those who are allergic to tree pollen or mold. you may be suffering symptoms this weekend. the asthma center in center city is reporting tree pollen is very high, and mold at the high level as well. so if you take medications, do so before victims starve and do what you can to limit your exposure to pollen. keep windows up in your home and car, wash your hair after being outside and wipe off your pets when they come inside. >>> good advice. >> it will be a nice weekend though. it will be tough for allergy sufferers but it should be a sunny weekend. >> tell easter bunny do

the f.d.a. has stopped short of taking the device off the warning on the box. josh: with heroin still topping the list of granite staters' biggest concerns, news 9 invited governor hassan to our studios live tonight to update the progress on the epidemic. jean: and a controversial new rule for new england fishermen is in effect tonight. and now to our u local hot shot and it's a cute one, this is little jose spending time on a swing during his very first trip to hampton beach. submit your pictures and video, join u local members by logging onto u what's all this nonsense about balls? pink balls, blue, yellow, red. it's hard to keep the whole thing straight. and all these so-called deals? well, they come with a lot of deal breakers. like when you leave the city u.s. cellular built a network to give you a stronger signal where the other guys don't. and as for deals? how's $300 back for every line you switch? $300! no ball nonsense. get $300 per line and a stronger signal, >> we see it all the time, and we see all throughout the kids and we find needles, in high s

well, the f.d.a. has had voluntary education for opioid prescribers in place since 2013 and has been actively encouraging doctors to take these voluntary education modules. but in more than two years, less than 12% of prescribers have actually completed f.d.a.'s voluntary education program. a survey of 1,000 physicians nationwide found that nearly one half of doctors erroneously reported that abuse deterrent formulations were less addictive than their counter parts. it's uncongressable that our doctors know so little about these potentially deadly painkillers. and i intend to call up amendment number 3382 later so that we can make consideration of the bill. the amendment would ensure that as a condition of receiving a license to prescribe opioids, that the recipient of the license is educated in the best practices for using opioids and the connection with addiction and with diversion. and i intend to call up that amendment later asking for consideration. so from my perspective, if we're going to have

the f.d.a. is very clear on what is. it certainly can provide feedback to you, but i would not change the way i take medication. i would not change the way i behave in terms of seeking medical attention based on a fit bit or apple watch. >> reporter: however, used for personal fitness goals, it's very beneficial. >> it's still a good tool. it makes me think, i need to go to the gym. i need to take my own steps. your wrist gets you to the gym, that's what really counts. >> a company spokesperson noted that fit bit's heart rate tracking received a good report. fit bit trackers are designed to provide meaningful data and not intended to be scientific or medical devices. you can find the latest on our website. >>> people being reminded to boil their water following a weekend water main break. they should boil their water for at least three minutes before cooking, making ice, or even brushing their teeth. freezing temperatures across much of our area. if you haven't yet, make sure to cover up any plants before you go to sleep.

they learned of the video friday and alerted the authorities. f.d.a. is conducting an investigation. kellogg's own investigation determined it was recorded at the memphis tennessee factory in 2014. the video is posted on our facebook page. jonathan: the first ever dissolved stent. they are looking into this but the f.d.a. has the questions about the safety and the effectiveness. they are highlighting how important is it to clean humidityfiers. they tested the water and found all the humidifiers had bacteria in the tank. two had heavy bacteria inside. and in the vapor. three had mold. >> i was surprised by the growth in the devices. mold can cause nation congestion or chest tightness or wheezing. >> you have to clean the humidifier every day to let it air dry before refilling it. jonathan: there is not much needed for the humidifiers with the moisture in the air today. doug hill is in the storm watch zer center with a check of the forecast. the current temperature, everybody is the same. the warm spot is manassas and dale city. the temperatures will fall

okay, how about a little "t" in a box or tie angle or something else that the f.d.a. or the food companies would like. the point is if someone cares enough to pick up a package, turn is over, look at the fine print on the ingredients, if they care enough to look just like they might care enough to look up whether or not there's high fructose corn syrup, just as they might care enough to see if there's peanuts because they might have a peanut allergy or to look to see how many calories. if they care enough to turn it over, a little symbol. well, all of those options are available under this type of reasonable compromise. now, it would appear on each product involved this interstate commerce. okay, so it's consistent, and that's a point made. it's clear, these symbols are clear. the public cares, gets educated. they know what to look for. it's easy to find. it's right there on the package. there is no sending you off on a wild goose chase through a phone tree and anle00 number. -- an 800 number. there's no proceeding to tell you you have to use a smartphone which many pe

the f.d.a. is taking comments about possible testing in that. john: a brush fire leads to tense moments in the sand hills. the structure burned ingal activity police think the driver was doing. barbara: some of you could run into fog this morning as we brace for severe weather later. don: patchy fog but thick in spots. we check the first alert doppler ended but we are under a there are two democratic visions for regulating wall street. one says it's okay to take millions from big banks and then tell them what to do. close the tax loopholes, and make them pay their fair share. then we can expand health care to all, and provide universal college education. will they like me? no. will they begin to play by the rules if i'm president? you better believe it. i'm bernie sanders and i approve this message. let's talk bus stop forecast. kids head out you may see a little patchy fog. it will be another warm humid walk to the bus with temperatures in the low 60's. that should be the normal high. 56 right now south hill. 59 roxboro and hillsborough. 61 loui

you can get the code on the f.d.a. website. barbara: a north carolina mom is in jail accused of keeping her children out of school more than three years. they say see kept them 10, 13 and 15 from attending school and the worse part the school was in walk distance of her home. officials are working to get them back in class but the transition may not be easy. they are three years behind. john: sad case. let's talk about something better the we have a nice force. don: we have a gorgeous friday shaping up. tkaeuday moves along sunshine. rain returns tomorrow. about 30% tomorrow. tomorrow night into sunday just about everybody will see showers. less than an inch at this point but could be a wet weekend. i will show you what is going on with a look into downtown raleigh and temperature is holding at 55 degrees. dew point 33, 43% humidity. r. r.d.u. flights won't be a problem. 57. from across the region 53 roxboro, 58 chapel hill. 47 in sanford, 52 smithfield. 57 fayetteville, 60 clinton and 48 louisburg. looking at the latest satell

to be prevent the promising new field of combination products from getting caught in red tape at the f.d.a. i mean by combination products, devices and drugs together. then a bill from senators wicker, klobuchar, bennet, collins and franken would increase the say patients would have in the f.d.a. approval process about treatments received in a clinical trial. then franken, nelson, isakson, brown had a bill to encourage companies to develop a treatment cure or vaccine for the zika virus. these were all adopted, but for these to become law, we have to pass our bill. we have to bring it to the floor this year and we have to do it in a bipartisan way and pass ou. the three markups, our third one will be in april. we'll consider 50 proposals. every single one of them has bipartisan support. there are two or three areas where we have a difference of opinion. i'm glad to see the senator fros here because one of the areas that we discussed this morning is one where he has been very important, and that is to have a surge of funding, additional funding for the national institutes of health. a number

addyl was rejected twice by the f.d.a. over concerns about its emily: new this morning. students are getting ready to take the s.a.t. this month. and they will find some big changes this year. first, the reading portion is more advanced. the number of words is the same as the old test; however, the passages are longer. and the reading level appears more advanced. next, the math section now takes a more integrated approach. it combines concepts. for example, a geometry concept could be involved in an algebra question. you need to understand both to answer it. and lastly, students taking the new s.a.t. will see more data analysis across the board. expect to see graphs and charts in all sections of the test. >> they're not adding a science section, but they're putting a lot of those types of skills all over the test so students are really being asked to understand data, to read charts and graphs, to interpret and then to make decisions on questions based on that. emily: the college board does now offer free test prep to help t

the f.d.a. is adding its strongest safety warning to the device called a "black box label." the serious risks include tearing of the uterus or fallopian tubes and severe allergic reaction. side effects range from chronic pain to autoimmune disorders like lupus and psoriasis. many women who have used the device are calling for a ban. emily: a legal victory for apple. the company to provide the f.b.i. with access to locked iphone data. the ruling comes in a routine brooklyn drug case, but it has much wider implications as apple stands its ground in dozens of other cases, including one in massachusetts. earlier this month, a california judge ordered apple to create software to help the f.b.i. hack the san bernardino shooter's iphone. randy: flowers lie on the hollywood walk of fame star for actor george kennedy. he died yesterday at the age of 91. kennedy won an oscar for "best supporting actor" for his role in 1967's "cool hand luke" as the boss of a southern chain gang. he was also known for his work in the "naked gun" movies and "airport." emily: the celtics out-jazz utah at

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the f.d.a. is checking with all stores around the country, right here including the ones we have in florida. so far, no one has gotten sick, though. chipotle's new food safety rules shut down a store in the boston area. four workers called in sick yesterday, one of them testing positive for the norovirus. they've had problems with that in the past. clean-up crews are already working on the restaurant and health inspectors will make sure it's safe before reopening. to be infected. the company is still reeling after a nearby store had to close. 150 customers with are diagnosed with norovirus last year. >>> your favorite italian dressing is about to get a lot more expensive because of a lack of rain. >> the cost of olive oil has spiked 20% in recent months. the jump in price is being blamed on the drought and disease that devastated a big part of europe's olive crop. a bad summer in 2014 caused the worst harvest in spain in nearly 20 years and in italy, millions of olive trees have been attacked by

. >> reporter: key west, florida, has applied to the f.d.a. to conduct a test using the same mosquitoes, but some residents are fighting it saying environmental impact. >> pelley: fascinating. jon, thank you. sush surgeons have been forced to remove the transplanted uterus that was hailed this week as a new hope for infertile women. we met the recipient, identified only as lindsey, at the cleveland clinic on monday, but the next day, there were unspecified complications. danger. don't let a cracked windshield ruin your plans. trust safelite. with safelite's exclusive "on my way text" you'll know exactly when we'll be there. giving you more time for what matters most. (team sing) safelite repair, safelite replace. getting the right nutrition each day is important, but drinking an entire full size nutritional drink can be a challenge. try new boost compact nutritional drink. the only drink that provides complete nutrition in half the size of other nutritional drinks. boost compact is filled with 10 grams of protein, plus 26 vitamins and minerals

. >> policeteria concerns at starbucks and the f.d.a. issuing a recall of the popular sausage and cheese breakfast sandwich aing ifing 200 starcks stores in texas and arkansas and oklahoma with no arkansas and oklahoma with no sicknesses report arkansas and oklahoma with no sicknesses report when i have an asthma attack... i feel scared. sometimes my parents have to take me to the hospital. i feel like a fish with no water. you know how to react to their asthma attacks. here's how to prevent them. call... visit... or call your doctor. because... forged out of bravery, sacrifice, and duty. from all corners of the country, a family for life. ♪ but whether they served in lands far away or communities close to home, some of these men and women may face difficult times or even crisis. but sometimes reaching out for help can be the most challenging and worthwhile mission of all. thankfully, friends, family, and communities are standing by their service members and veterans now more than ever. ♪ we're all in this together. when you recognize so

the abortion drug mifeprex was made more available under new rules from the f.d.a. a prescription will now require only two doctor visits rather than three, and the pill can be started up to 70 days after a missed period, before the maximum was 49 days. once known as r.u.486, the drug was approved in 2000. today, about a quarter of all abortions are induced with medication. tonight in north carolina, they are facing a business boycott overa law that critics consider anti-gay. this week, georgia's governor carolina's governor is defending his new law. here's mark strassmann. >> reporter: north carolina is roiled by backlash, boycott threats, and bigotry allegations over its new law called h.b.2. critics say it bars discrimination protection for people who are gay or transgender. the most talked about provision requires people to use public bathrooms that correspond with the gender on their birth certificate. supporters say to protect privacy. >> they don't want to believe we exist. >> reporter: jaquin carcano is a 27-year-old transgender man and a plaintiff in a feder

the f.d.a. insisted that bta is safe at food-grade levels. and campbell has used for over 40 years, but many worry it may raise the risk of cancer and who are hormonal problems. >>> it is windy out there tonight. what's causing all the wind? >> the storm system that brought us the rain this morning over nova scotia and deepening. and high pressure from the west you get the wind-tunnel effect over us. >> is it a trough? >> it is not really technically a to have, but we will get a trough next week. i love when you listen to me. >> i do. i try. >> it is not really a trough. double scan showing dry conditions out there tonight. and the action cam taking a look at the philadelphia museum of art and seeing the winds blowing. the winds of change blowing down cooler air tonight. and currently the wind gusts in philadelphia 40 miles per hour down from the peak of 46. winds diminishing a little bit. wilmington 40-mile-an-hour winds and reading reporting a wind gust 35 miles per hour. temperatures are cooling off. a high of 70 today and down to 54 degree

the f.d.a. proved it in 2014 and research suggested it was good for heart health and now it seeps that a component of the drug could officer heart rate and blood pressure. more studies are in the works to link or dispell the correlation. >> have it minute "d" is a no guy for arthritis in the knees, as far as slowing the progression of osteoporosis is controversial and researchers say there is no evidence it works. they found a slight improvement but not enough for people with arthritis in the knees to avoid surgery. >> and a new plan to add 2 cents tax on each ounce of sugary beverage so a 12 ounce can of coat would cost an extra 24 cents raising $3 billion a year to pay for disease prevention programs. groups and small business say it is a tax that unfairly targets one ready. berkeley okayed a one cent per ounce tax and a similar measure in san francisco failed. >> look at this moment at the marin humane society, posting this video showing a it frommed female dog spring become to life after bein

key west applied with the f.d.a. to use the same mosquitoes but it has run into opposition. >>> it is a sign amazon is moving forward with freight air business. they signed a lease for 20 cargo planes. the move appears to be part of a broader plan for amazon to build its own delivery system similar to ups and fed-ex. >>> before you head out this morning what are you going to have for lunch? do you know yet? you have to plan ahead. it is pack your lunch day. this is where you take time and make a sandwich and save money. dietitians recommend preparing ahead of time. make sure you have grab-and-go snacks and check out magazines and websites for new recipes and ideas. we have been talking about this people make the point sometimes at work you don't have time to sneak out and get lunch. >> if it is there you can eat when ever you want. >>> 6:15 is the time. let's get over to hilary zalla. >> it is a good time to get out the door if you can. if you are heading along i-4 it is taking nine minutes from i-75 to i-275 in tampa

the f.d.a. made the announcement ahead of schedule because the blood donation are affected.o has been getting donations from the united states because the virus has been is active in the country. >> major league baseball is going high-tech and the league has reached a deal to place ipad pros in the dugout using the device to access the newly developed video apps called mlb dugout. >> even panda, enjoy a selfie. >> this giant panda cub at the conservation and research city in southwest china was spending time with his human foster dad. they are bonding including hugging and kissing and they take good soleys together. look at that. >> but he filter as lot, and he is like, dad, you are if my light. >> you take it from a higher angle. >> we have a new 90 minutes of includes detail of raising the includes detail of raising the cam minimum thank you so much. did you say honey? hey, try some? mmm that is tasty. is it real? of course... are you? nope animated you know i'm always looking for real honey for honey nut cheerios well you've come to the right place. great, mind if i have

in august the f.d.a. the drug to treat low sexual desire the first of its kind approved for the problem. the results show that drug did not enhance most women's sexual life or increase the frequency of their even counters but linked to a higher risk of sleepiness and nausea. sleepiness and nausea. >> the sunrise right ball i was walking home. just picked us up two breakfast croissants for four bucks, when this bear attacked. with one swipe, it devoured one of the croissants. then jack showed up and took care of the beast, so i could escape. and that's what happened to your breakfast croissant. and yours? it survived. share it with yourself. freshly cracked egg with ham and bacon, or sausage, get two breakfast croissants for four bucks. >> if you are headed out the door the seven thing you need to know, breaking news in san francisco, a sweep is underway right now around decision street to move out the homeless. last weekend the city gave them 72 hours to vacate. >> march 1 but it looks like february. with

>> stephen: they're about to get things started, but before they do, one more thing-- the f.d.a. has approved the first generic version of viagra-- which is great news for everyone out there with a generic penis. >> tonight, stephen welcomes. jeff daniels. audra mcdonald. and mary elizabeth winstead. human. and now it's time for "the late show with stephen colbert"! ( cheers and applause ) ( cheers and applause ) >> stephen: that was so nice. >> jon: that was rail something. you didn't know. >> stephen: i'm glad bill was able to get a little couple of z's in the front row. very honored he would stop by. once again, happy friday, everybody. i just cannot get over the joy of knowing it's friday. friday is always special here at the "late show" because every friday we set up a hypothetical cage match between two things, donut versus bagel. with a nail gun. nail gun has the range advantage over the chainsaw, but neither animal has the opposable thumbs so it's a free-for-all. then we post those match-ups on twitter, america's number one place for mindless conflict. and you, the people,

in august the f.d.a. approved the drug to treat low sexual desire, the first-of-its-kind approved.it did not enhance most women emphasis sex life. or increase the protective their encounter. it was linked to a hire risk of being sleepy and nausea. >> health regulators add new warnings to a permanent contraceptive implant with the colds inserted into the tubes that cause the body to grow ten use and block the tube. many women complained of severe pain and pleading. pain and pleading. some requireed >> girl scout in southern california learned an pent lesson while selling cookies. >> a anyone-- nine-yea selling cookies with her mother and a pan handed her $100 for five becomes. she gave him $75 in change. he left. police later condition firmed the bill was a counterfeit. >> there are good people in this room. there are bad people. it was a good lesson to learn. >> the story has a happy ending while waiting for the officer to arrive a good samaritan heard the story and gave her a real $100. the woman said she did not want her to have a bad girl scout expense. girl scouts usually recom