in november of 2001 the fda approved the drug for only the first three indications but not the fourth acute pain. public citizen requested from fda a copy of the approval packets. and in early 2002 the fda posted on its website a complete copy of the requested approve package. but a few days later before public citizen staff saw the information and at the request of cyril the fda removed the information on its pack claiming that the information involved trade secrets and confidential information. in may 2002 a press release for touting dextra. the article was cosponsored and three of its five authors were employees of pharmacia. the fda released much of the information previously redacted from the approval package which showed that the fda had denied approval for treating acute pain because of safety concerns. in particular safety data from a trial in patients undergoing coronary bypass surgery -- the 2017 blueprint builds on the work of the fda's 2012 transparency task force which recommended that the agency among other things release complete response letters to shed light on why dr

through the recall process. fdahas also improved its recall classification process and now averages 13 to 15 days, down dramatically from a year earlier. furthermore, the agency is focused on providing more information to consumers in a number of ways could we now publicize recalls prior to classification. yesterday released a guidance to improve public awareness and additional recall areas and the commission are also not the fda will identify a way to share additional information that consumers are in recall such a specific stores or recalled food may have been sold. .. i would be happy to answer any questions you may have. >> thank you very much for your summary of your testimony. at this time the members will each have five minutes to ask questions of you. i will recognize myself for that purpose. i will start with you, if i may, mr. stern. the office of accountability office and previous audit reports back in 2009 had raised concerns about the fda monitoring of food recalls. retail grocery stores know about the

realm of acceptability for the fda to take an enforcement action of an issuing a warning letter? what's the typical? >> there's some variation by program. i say ordinarily. we go back within six months. in certain areas, clinical trials, for example, it tends to be longer because there's got to be enough data to actually monitor what's occurred. but this is -- this is not what ordinarily happens or what we should expect. >> are the delays of a recall more of a problem with dietary supplement products? >> i would say you know, there are -- this is a good answer. one of the issues that occurred here in these dietary supplements, there's an ingredient dmaa. there's some controversy about that. there has been some litigation related to that. so -- and i could follow up, we could follow up with you in some ways. i would just say where some of the issues are scientifically challenging, the firm did challenge some of the science about the safety of the ingredient in this case. >> and then final question on this line of thought.

in 2010, congress gave fda more power to retain the food. fizz ma was enacted to provide fda with authority to mandate a food recall. in addition to this law, previous audits by both the hhs, office of inspector general, and the government accountability office, made recommendations to fda to improve its food recall program. how has fda performed with food recalls in recent years with the new law and these recommendations? over the last two years, the hhs, oig looked at this question and last month released a report that contains findings and recommendations for fda. the oig report looked at 30 volumtoll tier recalls. the fda used mandatory recall authority only two times since enactment of physicfizz ma and all over the last four years. in some cases fda was slow to evaluate health hazards. took fda average of 47 days to complete an evaluation after learning of a planned food recall. the oig found that fda was slow in starting recalls. average leebt between recall began once fda new of the safety issue was 57 days. the report also raises que

foods and high priorities for the agency. fda has wide-ranging oversight responsibilities. in the foods area, fda is responsible for oversight and regulation of more than 300,000 registered food facilities and more than 12 million lines of imported food products per year. fda is also responsible for overseeing recalls of food products. in the most recent fiscal year, fda oversaw more than 3,600 recalls. the recent oig review of the selected group initiated between 2012 and 2015 found some unacceptable delays in the removal of food from the market. this group included a number of challenges including criminal behavior from a firm that had critical information, new technology used to link clinical samples to their source and key questions about how broad a recall should be. one of the most significant steps fda has taken was in april 2016. fda established a team of senior leaders charged with reviewing complex or unusual food safety situations in determining the proper action to address the problem. score, the strategic coordinated

when i was part of the transition in 2009 at fda where we met with about 60 different groups that were engaged with the agency. i noticed that many of them seemed to be mad at the fda and for very different reasons. in fact, they could be mad about the same decision the fda made from completely different vantage points. and as we went through just meeting with group after group after group, i realized that every single one of them, if they didn't understand an agency decision, would think about it as a worst case scenario. had is what it meant. they would bring all kinds of assumptions even if they were wildly different from group to group. it's unquestionably true that fda can handle a very challenging regulatory matter well, in fact, do a better job than any other agency in the world and if the answer is not explained can still fail in the court of public opinion. later when i was serving at fda i attended a conference where the agency announced that fda had worked with nih and industry to make available to researchers data from th

and the gold standard of the fda as the regulator. so i think that really does distinguish the biopharma enterprise from most other industries where the regulators are viewed as a necessary evil and bureaucracy that slows things down. certainly from the industry you will hear complaints about specific decisions or specific interactions that are had with fda. and that is to be expected and inevitable because there's so many different perspectives and complexities here. but i think it's almost universely recognized that without a robust and effective fda, we couldn't make the bio pharma innovation enterprise work. >> what is it about fda that investors want to hear, want to see? what kinds of information can come out of the agency? what kinds of explanations are people interested in? >> stepping back, first of all, i want to thank you for inviting me to be here, josh, and get the investment perspective kind of things and i want to thank on the blueprint you put out and the focus you're bringing to this extremely important issue because

scott gottlieb the commission of the fda. as you one of the 20% futures act aimed to catalyze a very important goal shared by all americans, to speed the pace at which scientific discoveries are translated into life-saving treatments and cures. we at nih actually really appreciate your leadership in passing this bipartisan act by a vote of 95 -4 innocent exactly one year ago today, december 7. this enhances authorities and resources in ways that will help us to achieve this goal. many thoughtful provisions are clear in the act such as reducing administrative burdens so our site is can do but more of the time to research, expanding our ability to award a prize for exceptionally creative ideas. and strengthening measures to protect patient privacy. in my written statement i submitted a comprehensive report on at nih has worked quickly to limit the provisions of the act. we are motivated by sense of urgency to the patients in need of breakthroughs. in my oral statement i would like to focus on the cures innovation fund. among the

>> ever. >> reporter: could the fda have stopped this? >> i don't know that we could have stopped it. i think a lot of people didn't do what they needed to do in the past or we wouldn't be in the situation we're in right now. >> reporter: watchdogs point to a timeline of missed opportunities to rein in the crisis starting with the approval of oxycontin in 1995. by 2013, with opioids ravaging the country, the fda approved another powerful opioid called zohydro, over the objections of a panel of experts who voted 11-2 against it. the epidemic has hit west virginia particularly hard. >> one little community of 340 people had 9 million pills coming into it. >> reporter: senator joe manchin spent a year lobbying the fda to put limits on prescription opioids like vicodin. >> i go up and testify before the advisory committee. boom, should have been a slam dunk, right? >> reporter: but it wasn't. between the fda and the dea, it took nearly two years for the change to go into effect. once it did, a billion fewer pills were prescribed. dr. gottlieb

we're committed to enhancing transparency throughout the work we do at fda. this is especially true when it comes to these efforts to have the potential to foster further research and discovery across the scientific community and clinical care. and we'll continue to seek additional opportunities to foster greater access to key scientific information and clarity around regulatory decisions wherever appropriate. the powerful synergy between high power data sets has been effect for over 50 years, long before the advent of the desktop commuter. arguably two of the most important and impactful initiatives undertaken in the post-war era. in the launching of the study in 1948 and the surgeon general's report on smoking in 1964. over the ensuing decades subsequent analysis new generations of participants, spouses and children helped revolutionize our understanding of the risk factors of card cardiovascular disease. the combination of better science and a better informed public led to a dramatic decline in mortality from all forms of cardiovascular disease including he

>>> this week, the fda approved the first device for the apple watch. and a veteran briefs us veterans in the workforce and sarah lacy feels repressed, and michael from cork and mike sullivan from fast company. in week on press here. good morning everyone, i'm scott mcgrew, the apple watch has been a big hit or miss for apple and it has a sensation for those focused on health. this mother and daughter experimenting with the watch for cnbc. >> i'm not sure that i understand how to use it well look, what time is it? how many steps did i walk today? and then, this is always curious. >> your heart rate. are you stressed right now? >> the watch is stressing me out. >> the latest technology is for the unhealthy. a company called alive core has approved the first medical accessory for the apple watch. hardware that allows it to perform regular ekgs on the wearer. we have the ceo of live core, the cop that makes the device. he is a former google vice president where he ran the company's social efforts joined by mike sullivan of fast company and michael koran of

gottlieb told us about several more aggressive new measures he's instituting at the fda. ommon lly prescribed painkille they will have to provide more training for doctors. he repackaging pills in smaller quantities so a trip to the dentist doesn't become a month-long supply. >>> we're going to dylan for a look at what's ahead in the orange room. >> we have a good one. you won't believe what a college you won't believe what a college student just did to try to fix my name's dustin. hey, dustin. grab a seat. woman: okay. moderator: nice to meet you. have you ever had car trouble in a place like this? (roaring of truck) yes and it was like the worst experience of my life. seven lanes of traffic and i was in the second lane. when i get into my car, i want to know that it's going to get me from point a to point b. well, then i have some good news. chevy is the only brand to receive j.d. power dependability awards for cars, trucks and suvs two years in a row. woman: wait! (laughing) i definitely feel like i'm in a dependable vehicle right now. woman 2: i want a chevy now. woman

and doctor scott gottlieb commissioner for the fda. this is the first of two hearings we plan to have on this topic. the second will be noticed for tuesday, january 23rd. senator murray and i each have an opening statement. then i will turn to senator alexander and casey for opening remarks they might have.after that will introduce the panel of witnesses and we will hear their testimonies and then each member will have up to five minutes for any remarks and questions. first i would like to welcome the chairman and thank him for giving me the opportunity to hold the devil today. this hearing discusses a topic that is critical to the national security and has seen many years of bipartisan work in this committee and in this congress. together we have developed and strengthened the grammar to ensure that we are prepared for chemical, biological, radiological and other nuclear threats with the potential to jeopardize the health of all americans. the pandemic and preparedness act of 2006 crater framework which is grown and changed as we have

joining us with more on the fda's agenda in the new year and a preview of the upcoming j.p. conference is fda commissioner dr. scott gottlieb also joining us is meg tirrell thank you for being with us today, doctor. gottlieb. >> thanks for having me. >> let's talk about generic drugs first. you have made this a big issue, you want this to be a priority this year and you've released two sets of guidelines, one is for the industry to tell them what they need do better, the other is for the fda internally. what keeps generic drugs from getting to market quicker? >> so we released these yesterday. the goal is to try to cut down on what we call multiple cycles of review. the reason why generic drugs were delayed getting to the market is because many times the applications would undergo multiple cycles of review, up to four on average. it would take four years to get a generic drug approved. we want to see more of these drugs get approved in the first cycle. that means the applications need to come in in better quality, so we put out the guidelines to the industry on how to improv

we are delighted to have you here and in that position at the fda. finally dr. redd the office of preparedness at the cdc it serves a number of rules under the framework building a strong relationship with state and local public health departments to prepare for and responding to emergency public health threats. cdc works to make sure we have the information we need in advance of the public health emerged. it houses an expansive epidemiology laboratory with data collection activities. we welcome all of you. let me say at the beginning that i believe the hurdle in our way is not innovation. the hurdle is government. clearly defining what it is and the certainty of a pathway for getting the approvals that we need for those to be deployed i keep along -- i hope you keep those in mind in the roles that you carry out to understanding on the front line to make this happen. >> good morning. distinguish members of the committee i assumed this role right before hurricane harvey struck texas it is been an interesting experience i appreciate the opportunity to appear before

nancy: so far, no word on if or when the approval could happen from the fda. but it can help women who cannot afford it or are unable to go. it is too bad we have the warm weather but rain. josh: it will stay cloudy tomorrow, but we will get a few hours later in the afternoon and early evening when we can enjoy it. the timing will be tight, but try to sneak in some easily see the cold front on the way. the temperatures hanging in the teens in parts of illinois. st. louis 22. they were in the mid-60's earlier today. the cold air pushing our way friday night going into early saturday morning. 57 right now, some areas hanging close to 60. very mild, getting a break from the rain. this is building in throughout the overnight and especially tomorrow morning. about 25, 50 to 55, degrees above where we are normally overnight. the southerly breeze and the cloud cover. the breeze working in tomorrow morning, we start off futurecast around 6:30. showers, more than likely dealing with wet weather getting to work. slower than normal. getting to the bus stop, gear. later in

maria: let me talk to you about the new fda commissioner, dr. ib, is he moving the approval process along getting drugs out there? he had a focus on come snreks generics. he talked about wants to go focus on the first to market generics that are important for the consumer and the patient and the system. we have seen a rise in generic approvals and an uptick. maria: we have been talking about the tax plan and what that means for the bottom line of corporations. you pack inquired meda. are you interested in using some of that savings to do another big deal this year? >> we have been steadfast on paying down our debt. our balance sheet has never been stronger. we just finished a $billion dollar share repurchase program. maria: i also spoke with the ceo of merck. and when i spoke with ken frazier he gave me an update on the progress they are making in the fight against cancer. >> if the american cancer society put out data showing the death rates of cancer has declined by 25% since 1991. a large part of that is the kind of treatments we have. these a

>> and why one prestigious museum now has a puppy on the payroll. >>> a new warning from the fda. cough medicines that contain opioids like codeine should never be given to children. those medications will now be labeled to make that clear. they'll also be labeled with reminders about the addiction dangers to adults. >>> another close call at san francisco international airport. the faa now investigating why an aeromexico plane nearly landed on the wrong runway tuesday within a mile of another aircraft before it was diverted. the airport had two similar incidents last year. >>> and we couldn't resist showing you the cutest new employee at the museum of fine arts in boston. meet riley, not a bomb-sniffing dog but a bug-sniffing dog. the weimaraner puppy was brought on board to use his exceptional sense of smell to find insects that could damage the works of art. let's face it, it's fun to have a four-legged friend around. we should all have one at the office. i have one in mine. >>> up next, a little boy's emotional homecoming with those who serve. next at 6, fleeing for her life, o

food safety does not monitor human grade. >> it should meet human grade standards. >> three times the fda guidance for lead in certain human food. and this brand had a product with 15 times the epa's mercury limits for drinking water. so this may also be found in human food and each brand also had products with much better results. so exactly how much is too much lead, mercury and the like for your pet? no set limits. the clean label project used the epa safe drinking water act for guidance. >> we had to rely on something. >> reporter: in response the fda said relying on the acceptable level for humans is not a sound approach for levels in dogs and cats, noting the size difference, and that humans drink for water. >> if we can't compare human food to pet food, there needs to be regulations. >> the fda reports 15 pet food recalls so far this year, none related to this report, but the epa says any level of those substances must be safe for the animal. while some companies say they don't test for these because there are no set limits, pet nutrition says they test their products and stand beh

the primary end point is really about how you get a drug approved through the fda and while our results were significant with that end point, they were actually sort of in the middle to the low end of the class. >> okay. >> and as you know, we have three big competitors in the space. and i think the investors were afraid that with that result that it might not be competitive. in contrast, the data on monday demonstrated it was well above the class, our competition demonstrated, in the same group of very, very severe patient. >> okay. why would i prefer your drug to the current allergan and amgen tests that are going on right now? >> yeah, so, again, it really boils down to how fast the drug works. we see that efficacy on day one. in addition, we're able to deliver a high number of patients to what we call higher levels of efficacy a third of the patients have a 75% reduction in their migraines and in addition, we saw those 15% that had zero migraines whatsoever and to date, none of the other programs have shown that level of etch fficacy. >> the others are pill form. yours is intravenou

if they've had a loss of blood, we have to bulk it up and give them the fluid. >> the fda reports onethe manufacturers says it's puerto rico plants are online again. could be months before production is fully restored. until then, some hospitals and clinics are forced to decide which patients get bags and whe when. even routine patients like wanda feeling guilty wondering she's using a bag that's critical. >> i've been there. i've been the cancer patient in the chair who's needed it, and it is not fair to them. >> the fda is monitoring other drugs manufactured in puerto rico and it says the saline shortage will improve in a couple weeks. we talked to one clinic in california that said it has enough sailing to get to february and after that it will have to reassess. >> bret: thank you. the republican accidents in congress continues tonight. california congressman darrell isis says he will -- darell iss issa. mike emanuel what's shaping up to be mayhem. >> i came to congress for four years and i have stayed for 18. >> california republican darrell i saw rejected the suggestion his distr

. >>> one of the biggest tobacco makers is now hoping the fda will approve one of its new smoke-free products. but will it be a healthier alternative or drive people back to cigarettes? >> plus, it's the newest fad many people are talking about. it's called hq trivia and a single game has up to a million players. cbs eye on the community... presented by target. art and history spark connections across cultures, igniting curiosity, conversation, and inspiration. the asian art museum, with the support of target, celebrates the unique achievements of asian art and cultures providing a catalyst for discovery and dialogue. the asian museum is here to make asian arts and culture relevant to everyone's life. to be culturally literate i think is important today. the impact is very great. it's so important that people come to the asian art museum because the reality is we all have a story to tell. it's what makes us who we are. target free sunday's allows people in the community to learn more about their heritage and enjoy beautiful artwork. we truly believe this museum is for all and target m

. >>> senior health officials from the fda, cdc and department of health and human services talked about their review of how to prepare for and respond to public health threats. >> like to call this hearing to order. the senate health, education, labor and pensions committee. this morning, we are holding a hearing titled facing the 21st century public health threats. our nation's preparedness and response capabilities. we will hear from dr. robert kadlick, assistant secretary for preparedness and response at the department of health and human services. dr. steven redd, director of the office of public health preparedness and response at the centers for disease control and prevention, and dr. scott g gottlieb, commissioner of the food and drug administration. this is the first of two hearings we plan to have on this topic. the second will be noticed for tuesday, january 23rd. senator murray and i each have an opening statement, then i'm going to turn to senator alexander and senator casey for any opening remarks they might have. after that, we will introduce our panel of witnesses and hea

he took refugeavoid sweden and an the "washington post" reports the fda issuediving kids cough and coldcine. serious side difficulties and even death. it is drugmakers to change the wording on labels to make sure children products. the fda said it's manufacturers add new safety warnings for adults. >>> and franco was a no-show at last night's critics' choice ayards. he won but he wasn't there to accept the award. it follows claims by five women who accuse him of sexual misconduct. francokco told cbs's stephen colbert that the stories are not accurate but he prides himself for taking responsibility for the things he's done. >>> still ahead, engaging facebook. the changes you will find on your news feed as the social media website aims for more meaningful interactions. plaque psoriasis,... ...isn't it time to let the real you shine through? maybe it's time for otezla (apremilast). otezla is not an injection or a cream. it's a pill that treats plaque psoriasis differently. with otezla, 75% clearer skin is achievable after just 4 months,... ...with reduced redness,... ...thickness, and scal

i'll ask a former head of the fda. >>> but first, he said it. on that, i have no doubt, and i think he knew exactly what he was doing. the profanity that the oxford dictionary defines as an extremely dirty, shabby or otherwise unpleasant place, ben zimmer who writes a language column in the "wall street journal" told "the washington post" it's a word commonly spoken among friends but rarely written down or documented. true, we've all heard it. some of us have said it, me included, but he should not have, and certainly not in this context, because regardless of whether the word enters the vocabulary of others, it's beneath the dignity of the office of the president, and when a president uses such a word, he triggers a slur being whispered down the lane. marty barron, the the editor of "the washington post," which was first to break this story, told "the washingtonian" when the president says it, we'll use it verbatim. that's our policy. we discussed it quickly, but there was no debate." nor was there any defense in the fact other leaders use the s

it comes from the fda. ntral organization within the federal government, it can make sure that we do a better job not only to our physicians but also to our schools, our parents, to all of us. look, we need to see opioids in a completely different light. these are very powerful addictive drugs. you'll remember certainly in our parents and our grandparents' generations, it's different kind of drug, but nicotine. we used to view nicotine as something that was pleasurable and enjoyable. but we really have one of the great public health successes and part of the problem when it comes to addiction is that substance my friend or is it going to do me harm? so we have to change our national perception. >> dr. kessler, final point. it has to do with the issue of supply. i pulled something of significance from your essay in the times. we need to rethink how the federal government carries out this mission. the food and drug administration in approving new opioid drugs puts more opioids in the marketplace because these

the fda manufacturers add new safety warnings for adults. >>> and "usa today" says james franco was ahow at last night's critics' choice ayards. he won but he wasn't there to accept the award. it follows claims by five women who accuse him of sexual misconduct. franco told cbs's stephen colbert that the stories are not accurate but he prides himself for taking responsibility for the things he's done. >>> still ahead, engaging facebook. the changes you will find on your news feed as the social media website aims for more meaningful interactions. plaque . ...isn't it time to let the real you shine through? maybe it's time for otezla (apremilast). otezla is not an injection or a cream. it's a pill that treats plaque psoriasis differently. with otezla, 75% clearer skin is achievable after just 4 months,... s of plaques. and the otezla prescribing information has... ...no requirement for routine lab monitoring. don't use if you're allergic to otezla. otezla may cause severe diarrhea, nausea, or vomiting. tell your doctor if these occur. otezla is associated with an increased... ...risk of

. >>> the "washington post" reports the fda issued a warning against giving kids cough and cold medicineious side effects include breathing difficulties and even death. it is requiring drugmakers to change the wording on labels to make sure children younger than 18 should not use the products. the fda also said it's making manufacturer s add new safety warnings for adults. >>> and "usa today" says james franco was a no-show at last night's critics' choice awards. he won but he wasn't there to accept the award. it follows claims by five women who accuse him of sexual misconduct. franco told cbs's stephen colbert earlier in the week that the stories are not accurate, but he prides himself on taking responsibility for the things that he's done. >>> still ahead, engaging facebook. the changes you will find on your news feed as the social media website aims for more meaningful interactions. aims for more meaningful interactions. plaque . ...isn't it time to let the real you shine through? maybe it's time for otezla (apremilast). otezla is not an injection or a cream. it's a pill that treats p

the fda is also requiring manufacturers to add new safety warnings on medications cents with codeine d hydrocodone for adults, including an expanded box warning, which is the most prominent kinds. i'm stephanie stahl, cbs-3, " eyewitness news." >> well, if you're lucky enough to be going to the big game tomorrow, one eagles player wants to you bring the noise. coming up: hear why it is so important for eagles fans to be loud at the linc. that is next in sports. stay with us. pro tip: gianraspberries for prices on produce. john... strawberries for amy... what's a jicama? thanks! take a fresh look at giant's produce prices. >> we are a little more than 24 hours away before the nfc championship game kicks off. yesterday the team at the practice facility to get in a work out at the linc. eagles keeping the same game plan as last week of the falcons in terms of practicing at the linc. last week we all watched vikings come down to the final play. case, for 61-yard touchdown, to win the game. eagles quarterback nick foles says the fans will be a major factor. >> i can't wait. our fans, i hop

. >>> plus the fda looks at the new cleaner alternative to cigarettes. we'll take you to canada where they're already learning the potential benefits and risks. >>> before he hosts sunday's grammy awards, james corden comes to studio 57 to tell us how this year's show will be different. >> can't wait. but we begin this morning with today's opener, >> my one thoughas out of there, justup. they were running. >> terrifying. >> kentucky mourns after a deadly school shooting. >> this is a wound that's going to take a long tomb to heime to >> robert mueller looking to question president trump about james comey. >> we're still in play. we can try and maybe even win. >> the state department said multiple u.s. citizens were killed and injured during a weekend attack in a luxury hotel in kabul, afghanistan. >>> larry nassar, american sports tock tore for usa gymnastics sentenced today. >> i can't put into words how much i hate you. >> tammie duckworth is about to make history. the first u.s. senator to give birth while in office. >> all that -- >> lebron james, 30

the hour. phillip morris shares rising even after setbacks yesterday. an fda it's cigarette alternative failed to show tobacco-related health problems. joining us is taylor riggs. this was not great news but the stock is rising. taylor: some analysts said this is not a final ruling, take a deep breath. the product is called -- it is a heat, not burn. similar to an e-cigarette. reductiono show a and health risks. we have a chart of e-cigarette users. is it the substitute, a gateway drug? users areernative actually current sigrid users. only 11% of e-cigarette users have never used sick arrest before -- cigarettes before. 9427. you can see what a are spending billions and billions of dollars to research alternatives. annual sales are about $300 billion. you can see by they are trying to find different revenue opportunities. shery: i understand why the stock would be higher. i have seen many of my friends smoke, but then switch to these e-cigarettes. the heat not burn. david: this is something different from e-cigarettes. what do they have to do to get this appro

we can speak that up, especially with help from the fda. e current health crisis around this is numb -- that is number one, more people died from opioid overdoses than car crashes. >> what will this machine look like and what will we know that we don't know today? thesee years from today, types of machines will not be used much, because they will be sequence thetake entire genome for $100 that you wouldn't bother to get the subsets of information. just to the whole thing, and it will be cheap and accurate. the information five years from now, i think more people will do their genome, it will be in their medical record, and when they need a truck freight particularfor a treatment, a doctor will look and say if this is the right dose are right drug for that person. the whole idea of correlating drug response, it is right for exploration, and in five years will see that. think mostom now, i babies will have their genome sequence from the time of birth, and that can be planned and make sure they get the best possible kind of nutrition, medical c

the fda green-lighted ocrevus. >> just slowing down the progression. if nothing else, it, lows you to keep doing the things you're doing longer. >> reporter: cartee removes a patient's t cells, then modifies them in the lab to treat cancer cells. >> this is a brand new way to treat cancer. >> they reported a sharp rise in cancer sale cel -- cancer cells in gen xers. >> i didn't even know young people could get colorectal cancer. >>> a mother had the first boy delivered from a transplanted uterus. >> there was something so excite being this. because the patients are so excited. >> a team of doctors repaired a faulty gene in a human embryo for the first time. the controversial process could help prevent thousands of disorders. and two major studies suggests drinking coffee, caffeinated or decaf, will help you live longer. researchers said the anti- oxidants found in coffee may offer protective benefits. that's a look at this story's top stories. >> 2017 was a big year, with moviegoers spending billions of dollars. >>> big screen hits like star wars, the

>> second, it's a highly unmedical need-mile fibrosis is a rare cancer and at the same time up until now there's been one fdad drug ever for the disease. the product that we acquired through the impact biomedicine deal actually works for patients who have progressed where they have no other therapeutic options for the disease, and it also rescues patients who get the standard of care so we think we've got a very nice market to come into. highly underserved it's a hematology play and, of course, that's celgene >> the deal is poe tonksly up to $6 billion more including sale goals. there were some concerns earlier with this. is there a risk it doesn't get through the fda? >> there's always a risk a medicine doesn't get through the fda. as best as we can tell that is de-risked asset that's ready to file the mda will come together by celgene and impact and look to file the side effect that you're talking about is a disease or a condition which is a b1 thymine deficiency in a database with 900 patients the indent dense of this is less than 1% show back to benefit risk when you have no other therapeutic options and

oversight investigations how they hearing on the issue last week with representatives from hhs and the fda. [inaudible conversations]

for the only fda-approved otc weight loss aid, try alli®. any could hurt american >> live from the cbs broadcast center in philadelphia. this is cbs-3 "eyewitness news ". >> good morning, i'm solomon, jury selection for bill cosby's retrial and sexual assault charges will begin march 29. >> ♪ ♪ >> ♪ ♪ cosby's surprised many a when h germantown jazz club, the first since his sexual allegations first came to light. >> matt looks like we need our umbrellas today? >> rain jacket, umbrella, boot all needed because it will be a wet tuesday across the entire delaware valley. we had some rain showers early on then philly got a quick break, but now starting to fill back in on storm scan3. and you can really see that our next band already pushing in to philly, and as you head little further north the more moderate to heavy rainfall up into the lehigh valley as well be a wet tuesday, temperatures, though going to feel spring like, 64, meisha also watch for rumble every thunder later this afternoon, as well. >> all right thank you so much. matt rain post

but the fda can still allow the product to be sold in this country. >>> and there's a new colonel sandeders. ♪ i'm colonel sanders, same as always ♪ >> his wife is due to pitch the kentucky fried chicken. her outfit is a bit different, has a glittery shine and fringe on the back. her voice, right? >> diane king hall at the new york stock exchange. thank you so much, diane. >> all right. >>> still ahead, saving money on your prescription drugs. >> reporter: using your insurance to fill a prescription can actually be more expensive than just paying cash. i'm brook silva-braga with why this is happening and how to get the best price. and if you have heart failure, entrusting your heart to entresto may help. entresto is a heart failure medicine that helps improve your heart's ability to pump blood to the body. in the largest heart failure study ever, entresto was proven superior at helping people stay alive and out of the hospital compared to a leading heart failure medicine. it can cause harm or death to an unborn baby. don't take entresto if pregnant. don't take entresto with an ace takin

it's the first time that consumer reports has issued a report before the fda and cdc. >> it's unusual, we have never been in the situation before, where, a foreign government that we share a food supply with has warned its citizens. and the u.s. government is not doing it. >> at the foods, some customers had second thoughts about their salad selection. >> i think i will put it back. >> this man was warned about buying romaine. >> i was told by my girlfriend's mom to not get the rowmaine let us. >> apple confirmed that all mac and ios devices are affected by the flaws in the chips. they leave all the computing devices in the world vulnerable to hackers. there's software updates being issued to fix the flaws. one lawsuit has been filed in san jose, seeking class action status and compensation for those that bought vulnerable int intel chips or computers. >> alex trebec is recovering after brain surgery because of blood clots on his brain. >> the prognosis is excellent and i expect to be back in the studio taping more jeopardy programs very, very soon. >> the 77-year-old thanked fans for

. >> reporter: it could be weeks before the cdc and the fda pinpoint the cause. gabe gutierrez, nbc news, atlanta. >>> coming up here tonight, luck of the draw. why a hotly contested race was decided by chance. >>> if you ever needed a reminder that every vote counts, today a random drawing was held to decide the outcome of an election in the virginia house of delegates that was still died after a recount and legal battle. a republicans' name was chosen from a bowl giving him the seat and allowing the statehouse gop to hold a majority. but the democrat in the race has not conceded. under state law the loser in the drawing can demand a second recount. >>> the nation's cancer death rate has fallen again dropping 26% since 1991 according to a new report from the american cancer society. it cites significant decreases in death rates from the four major types, lung, breast, prostate and colorectal. the report credits huge declines in smoking and better treatment. >>> and baby, it's cold outside, but lotto fever couldn't be hotter. no winners in wednesday's mega millio

health watch, a device to quickly diagnose cases of severe stroke has received the green light from the fda. e.r. doctors are using this portable adviser to determine if patients suffered severe stroke. the cerebro tech visor looks for changes in blood flow. it takes 30 seconds to analyze fluids and doctors say that the goal is to quickly identify patients who had a severe stroke so they can receive immediate treatment. >> as someone is having a stroke, they're losing many neurons over second. >> stroke is leading cause of disability in the united states according to american stroke association. >>> apple is facing new pressure to curb what's called children and teens addiction to its smart phones. two influential investors are asking the tech giant to make changes to software so parents can limit their children's phone use. the california states teachers retirement system sent a letter saying there is a clear need for apple to offer more choices and tools to help them ensure that young consumers are using the products in an optimal manner. >> the way i would hope it works is apple does res