when she sees the sequence, it sends her scrambling. >> it was late friday night/early sunday morningt i got the ski consequence. >> at 6:00 on saturday the 11th of january with the latest brr bc -- >> got up the next morning and was in my bedroom in front of my computer basically huddled over in my pjs designing the vaccine. for a normal vaccine program, it takes up to ten years. but we didn't have that luxury. >> professor lam works at the university of oxford. one of the world's preeminent centers for infectious disease research. >> the vaccines trickier body into thinking you have an infection. so you want a vaccine somewhat to mimic, to copy a natural infection. >> facing infection, our bodies naturally fight back. with antibodies. antibodies are a powerful defensive weapon against invaders. when a coronavirus attacks antibodies bind to the spike protein, blocking the virus so it can't invade cells. as our bodies fight off the virus, our blood becomes filled with these antibodies, which also helps protect us from being infected again. with the vaccine, the aim is to induce these

since january, the cdc has increased the sequencing output 75-fold. on january 25, the cdc ramped up the strain surveillance system to begin requesting 750 weekly from jurisdictions for sequencing, virus isolation and characterization. in addition, the cdc awarded multiple contracts to increase the number of specimens received per week, going from 6000 per week to more than 22,000. combined with the efforts of state and local public health laboratories as well as collaborations with academic institutions, the u.s. is sequencing near the 8% of the approximately 450,000 covid-19 cases. with the current capacity in our nation coming down, we are on our way to sequencing even a higher percentage of cases which i consider a tremendous accomplishment. the cdc has made significant strides to make our genomic data more available through a dashboard on our covid data tracker website. this site is updated weekly with the prevalence of sars covid 2 variants at the state and national level. we look forward to continued advancements in this area with additional inv

okay i read this part of the dna genetic sequence. them we use the messenger rna and then to make part of the spike protein with part of the coronavirus that is what it does it goes to the manufacturing region of the cells with that horrible spike protein because in the immune system that's not supposed to be there and then the immune system is prepared. that iswi how we prevent corona. that is messenger rna. and that guide says i want you to cut to the genetic material here at this gene. if youen call it crisper or messenger rna it is still that four letter nucleic acid from the rna that goes around and cut things up. >> the way you framing it makes so much sense now i get it. you do talk about in the beginning and in the end with covid-19 the pandemic that we are in, first of all i want to ask you behind the scenes, you started this way beforel we knew what covid-19 was. how could you capture all of that? because pretty much the whole back part of the book the end talks about the idea of genetic editing and corona and future viruses.

with academic institutions the united states is now sequencing 8% of the approximately 450,000 cases weekly. with current capacity, we are on our way to sequencing even higher percentages which i consider a tremendous accomplishment. cdc has made significant strides to make our genomic surveillance data more accessible to the public through an interactive dashboard. this site is updated weekly with prevalence of variants at the national, regional and state level. we look forward to continued advancement with additional investments made by the american rescue plan which provide $1.7 million to strengthen and expand much-needed activities and workforce related to genomic sequencing, epidemiology, analytics and surveillance. from a global spread perspective cdc is sequencing capacity in 50 countries like india, brazil, and south africa. this includes defining standardized approaches, providing technical assistance and a broader research community. as we mark 100 days of this administration i'm probably have collaborated with numerous partners to expand genomic sequencing and what that m

the sequencing of the vaccine gets determined in january. working through the weekend and then you have an idea what will work as a vaccine? >> absolutely. you know why that is? >> no, i don't! no one knows why that is. >> it's because we went into that weekend very prepared. we'd worked on coronavirus vaccines for the previous six years. and we knew exactly what to do. and we were actually waiting patiently for the sequences because we were so ready to start to make a vaccine in case that the virus did become a pandemic. >> you knew this kind of pandemic was both likely and surely on the way at some point but you don't know when, like an earthquake. >> coronaviruses have been giving us a hint over and over in history before. there was sars and then mers and so we kind of knew that coronaviruses as a viral family has pandemic potential. and so, we prepared for it. >> dr. corbett, this is a concern that many people has raised. they think the vaccine was developed very fast. could you explaining does this type of process of development going o

you know the sequence of the virus. we know the sequence for the codes of the surface protein. it is very simple. it is the easiest to construct. i have not seen anything yet beginning a phase three trial there. host: our next call is from new york. caller: good morning. he had question. could you offer an opinion as to what you think might be their motive? guest: right. it is hard to watch. looking at the reporting system data and saying thousands of people have died from this vaccine is holy irresponsible. it is investigated to make sure that there is a clear cause. that has always been the case. there has not been one person who has died from this vaccine. it is theoretically possible -- two to five people could have a severe allergic reaction called anaphylaxis. i could happen, but even that has not happened. i do not know why he does what he does. i wish i did. i am amazed that he is allowed to do it. he gets on television and scares people away from the vaccine, putting them at unnecessary risk and a possibly fatal outcome. it is no different than shouting fire in a crowd

really the sequencing wasn't enough and that is why i trace it back its origin in which my belief that i got this easy is difficult if you see it and wanted it out it leaves the sequencing of the virus is easy on the. net is enough circumstantial evidence to see that this particular into the area it has it's on even now the 1.617 that you probably are and i can see it's a cause and effect relationship but as that's also the action is clearly strong. probably causing the it's not present all over the country i'm still that we've. so india together with south africa has led the proposals for a waiver of vaccine pathans how significant would such a waiver be for india and the shirt in the short and the long term. it's humans it would this is a. matter you know i mean you don't see a situation like this i'm sure. they are manufactured however if you look at it in class if you use vaccines that is. the way to even find lot of buyer manufacturers or seat of the biggest manufacturer in the world i'm not. seeing enough doses off what they thought they'd more off so we shouldn't get in the fact

the sequence of events last been piece together. on september 28th, 2018 at 6 o 2 p n. a 7.2 magnitude earthquake struck 80 kilometers north of par lou. the epi center correctly identified by the tsunami monitoring center in jakarta did not directly trigger the tsunami. the seismic waves travelled through the cross at the extremely high speed of 900 kilometers per hour, generating a fold that opened up across the entire bay. that triggered land flies all along the coast, which in turn generated his theories of many to nami. the energy of all these many tsunamis accumulated in the depression of the bay combining to form a powerful wave that swept across the town, herman fruits and cost us no luck as the investigation has come to an end. the reconstruction of the bay of pollute through nami will help improve warning systems all over the world. we used to think that's synonymous. only that i can areas where you have some duction zones. we now know just like one company here. today i'm going to strike pretty much any place where you're going to have an earthquake . we are ve

every country where we had the chance to sequence a virus, it had so much identity to the won sequence, and that's roots out all this e cigarette and all the other theories that the chinese authorities have come up with since actually january 2020. i think patients 0 we are in a completely different world to the child to the spanish flu. and as an example, when i was in south korea, i didn't take us very long to identify patients 0 during the outbreak for the most virus. the same goes to saudi arabia, so we china, we will hon with all the development that china has accomplished. i think it would have been much easier to get us to patients. here is, here is a little strategy for our recording from china. if china feels very confident about every think, it has gone so far, they have no reason not to allow us access to the off the wall as a clinic. why dr. lie used to work. and many of us strongly believe that the cluster or the center point of the pandemic started there. and if that's the case, then they have, there is no reason why they shouldn't release the information of what happened

really the sequencing wasn't enough in time and that is why tracing back its origin in which month it i got this easy it's difficult to see it and want to dig out it leaves the sequencing of the virus is easy on the small but very easy enough circumstantial evidence to say that this particular area that we're going to be and it has its or even now the $1.00 that you've probably actually and i can see it's a cause and effect relationship but does that somebody actually is really strong that you probably think that the it's not present all over the country i'm still not even is there. so the india together with south africa has led the proposals for a waiver on the vaccine patents how significant would such a waiver be for india and the shirt in the short and the long term. it's humans that would this is a good idea meg you know i mean you don't see a situation like this. format fracture however if you look at it. if you use vaccines that is in the way even refined lot of buyers manufacturers or seat i mean the biggest manufacturer in the world i'm not going off the seeing enough of tho

the sequence of events that unami should 1st and this made houses collapse, or where do they collapse because of the earthquake and was from now me famous them off. what one of the people doing, why is it that some people died and some people did well, i, the to research is want to determine how the disaster unfolded their goal to trace the scene or me back to the event that triggered the wave. the cost us, you know, like, has goes to meet survivors in a small fishing town of $1.00 when the wave hits come, do la teeth was on his boat, 100 meters from the shore. also both of those young are when the 1st ways came in there was a big tremor and when my dad was that he got pop, could you see the tremors on the boat? yeah. yeah. just because the whole goal was rocking because the water level had drunk, the boat had run the ground. what they could do either that and she stayed with a boat of the west. did you stay on the boat? you went about did upon the forgot to hold onto the mash. yep. and then i saw the wave approaching in the distance. it 2 separate sally was very fast. 2 can be reache

you really have to piece like in the puzzle, the sequence of events that unami she'd 1st and this made houses collapse or where did they collapse because of the earthquake and this phenomena finished them off? what were the people doing? why is it that some people died and some people, the, well i, the to research is want to determine how the disaster unfolded. they go to trace that scene army back to the event, the trigger, the wave cost us, you know, lock has goes to meet survivors. in the small fishing town of one when the waste heat pump, duleigh teeth was on his boat, 100 meters from the shore boat go to a bar when the 1st wave came in, there was a big tremor. and when my dad got pop, could you see the trimmers on the boat out? yeah. just got the whole boat was rocking because the water level had dropped. the boat had run aground, up on what it could go, that she stayed with the boat of the why did you stay on the boat you went about did upon the my thing i forgot to hold onto the nation. ok. and then i saw the wave approaching and distance it to jump up. sally was very fast to ca

the virus it had so much identity to the wuhan sequencehe theories about the e-cigarettes and whatnot that the chinese came up with were from january 2020, we are in a different world to the spanish flu and as an example when i was in south korea it did not take us long to identify patient zero during the outbreak with the first virus. the same goes to saudi arabia. with china, with wuhan, with the development china has accomplished, i think it would have been much easier to get us to patient zero. here is a strategy for our colleague from china. if china feels very confident about everything it has done so far, they have no reason not to allow us access to the clinic where the doctor, dr. lai used to work. many of us believe the cluster, the center point of the pandemic started there. if that is the case there's no reason they should not release information of what happened there because from wuhan and the information we got from several scientists in china and we have not heard from them unfortunately since january 2020, we don't know wh

mention which which really needs to be emphasized is that there will minority civilian casualties in the sequence that you talking about and the reason for that is because we gave if anybody that is at fault is noticing now with advance notice in order to make sure that no june of this no civilians would be in that particular checklist and we appreciate it. if if i can just follow up in there so we certainly appreciate the word i'm hearing from you but as you well know the israeli military has so far provided no evidence of hamas activity in the building associated press says it was in that building for 15 years and had no indication. was operating there they also say they actively check because they would never knowingly put their journalists at risk and they're calling on your government to provide evidence for the justification for attacking the building will you provide that evidence rather then providing the sound bites we hear from you which we do appreciate. i think you can imagine that might be a lot easier if i could provide evidence to you right now. during this this poor old cost and i

we plan the separation sequence to get about 10 kilometers below the station.hat is where we executed maneuvers. that orbit is a safe orbit. right around 1:03 a.m., that is when the burn happened. it took 17 minutes to execute that burn. around 150 6:00 a.m., -- 150 6:00 a.m., as we dock from station during the sequence it went great. just as we expected. the entry went phenomenally well. i had to talk to the spacex team for building such a great vehicle. it was phenomenal for some. we have a lot of confidence in this night recovery based on the cargo mission. that we landed in january when spacex recovered that vehicle, as well. we had a couple lessons learned from the demo to mission. we had some slightly high readings. today we had some of that. it performed flawlessly. you might remember we have some boats in the area. today the coast guard had several assets on scene and patrolled the area. we had no leisure boats within the landing zone. that was much better than last time. overall, a great flight. we recovered the two parachutes in the four main parachut

yeah, i think the thing to say is that not everybody has their sample sequenced. taking a sample, we can get a good idea of what's happening over all, but it's difficult to pinpoint individuals if they've not had their sample sink which. the next question comes from roy. has it been established whether the current vaccines give protection against the indian variant? if so, what sort of efficiency do they have against it compared with other strains? professor griffiths, your thoughts on that? i think this is really one for professor hunter. he's more up—to—date with the most recent work. i'm going to pass it to him. 0k. yeah, we don't know... there are actually three indian variants. the first one that was discovered in the uk dates back to about late february. we do know that that one was more resistant to vaccine than the kent variant. it was controlled by vaccine, but not as well. it's not a yes or no thing, it's often a gradual thing. with the indian variant two, one that's actually increasing quite rapidly, that lost one of its escape mutations. so, although th

so, we certainly did that a lot for the sequence where there's a minefield, the people in trucks running used a combination of practical shot filmed elements, but also cg explosions which had to incidentally match exactly the practical ones cos they were right next to each other. another major event in the end battle scene where a building is simultaneously blown up by an inverted group of people and a normal group of people, so it's simultaneously exploding and imploding. so, we built two large, or there were one third scale ten—storey buildings, two matching buildings, and we filmed each of them from a matching camera angle, and we blew one up at the top and one at the bottom. and then we could reverse the film and composite the two together, reverse one of the films and composite the two together, so this building had this sort of simultaneous exploding and imploding event. this reversing the flow of time, doesn't us being here now- mean it never happened? talks backwards. ok, i think spencer's got a bit carried away. as ever, you can find us in the right order on social media — youtu

the sequence is very interesting to follow and where it begins there is great concern about having a particular idea of the counterparty what is the counterpart. it's interesting to watch how that unfolds. sontag writes the interpretation thing we should treat everything the same. we should enjoy everything. nobody would say that in 1945. >> you know i think the concept is -- of freedom is when you use to unite many of these periods or analyses and what we just talked about is a progression in the post-war era to a place where freedom becomes a true value. would that be a fair way to explain it? >> the obvious reason for that is in the cold war the united states -- freedom of expression because the alternative soviet model was more centered. speakers were banned and so forth so was a big selling point for the u.s.. it becomes almost a slogan of the period. everybody uses freedom to justify what the government stands for saberi goldwater in the defense of liberty and john kennedy used it. george wallace uses it read jack hayes uses it. they'll use it and we have terms like that today t

the dna . this genetic sequence. make this protein so when we use messenger rna for vaccines, we simply coded in a part of the site protein of the coronavirus. that's what the mrna vaccines do. it goes in the manufacturing region of ourselves and the next fragments of that horrible spike cookie. why? because our immune system sees it and says that's not supposed to be around and our immune system is prepared the next time it sees a spike protein, it will kill and that's how we prevent coronavirus so that's messenger rna and its in a similar snippet of rna can serve as a guide. that's called a guide rna that's the guide in the crispr system that takes the enzyme system and says i want you to cut the genetic material here at this gene. so whether you call it crispr rna or guide rna or messenger rna, it's still that four letter nucleic acid call rna and its stories around and cut thingsup and builds proteins . >> the way you frame it makes so much sense. so you do talk about in the beginning and in the end getting into t

around 1 56 am as i said the vehicle to a great flew flawlessly as we undock from station doing the sequence of maneuvers the trunk jettisoned went great just as we would expect and the deorbit burn and the entry went phenomenally well as did the parachute deploy my hat's off to the space x. team for building such a great vehicle and also their recovery operations tonight was was phenomenal 1st time they've done the crew vehicle at night we have a lot of confidence in this tight recovery based on the cargo mission that we flew and landed in january with space x. and they recovered that vehicle as well. you know we had a couple lessons learned from the demo 2 mission. if people remember we had some slightly high hyperball readings today we had none of that with the vehicle was fully it was performed flawlessly and last time a you may remember we had some some boats in the area today the united states coast guard had several assets on scene and patrol that area we had no leisure boats within the ellipse that we cleared for landing so that was much much better than last time overall just a grea

the data on sequencing that is publicly available on the cdc website is from the end of last month.o what are the proportions you are finding of the india variant, and what is the outlook for the next four weeks? dr. walensky: thank you for that question. i don't have that off the top of my head. it does take some time for us to do the sequence and analysis, which is why it is a bit delayed from week to week. i will get back in touch with you and present those data as soon as we have them. >> i will use that to emphasize the final point as we close, which is dr. fauci's very promising news that the vaccines we have available to us in the u.s. are effective against the indian variant. it is all the more reason why it is important for all of us who have the opportunity to get vaccinated do so, because we have seen the devastation these variants can cause in other countries. we should not feel this can't happen here. with that, i want to thank everybody for attending. have a great day. ♪ announcer: on wednesday morning, the director of the cdc testifies on the president's 2022 budget r

the sequencing of the vaccine, it gets determined in january. through the weekend by the end of the weekend you have your idea for what is going to work as a vaccine? >> absolutely. you know why that is? >> no, i don't. no one knows why that is! >> it is because we went into that weekend very prepared. we had worked on coronavirus vaccines for the previous six years, and we knew exactly what to do. we were actually waiting patiently for those sequences because we were so ready to start to make a vaccine in case that the virus did become a pandemic like we are seeing. now >> that is because you knew that this kind of pandemic was both likely and surely on the way at some point. you just don't know when, it's kind of like an earthquake. >> yes. coronavirus has given us a hint over and over in history before. there was sars, then -- you kind of new, that coronavirus as a viral family had pandemic potential. and so, we prepared for it. >> dr. corbett, this is a concern that many people have raised, they think that the vaccine was developed a very ver

new video obtained by cnn shows the sequence of events that led to the death of ronald green. custody. a warning, some of the images you're about to see are very disturbing. >> oh, no -- okay. okay,

and i specifically chose album number 11 because it is the only source that includes an elaborate sequence by an anonymous photographer without additions of commercial images in between it was donated to chs the same year. so 1906. and so while recent scholarship has paid attention to such anonymous prints of the earthquake the album as historical source is mentioned only in passing and so album number 11 provides us with a useful starting point for understanding their social function. so starting with a short documentation of life and refugee camps the album mainly consists of a walking tour through byrne districts, it documents damage of specific sites including the maker's neighborhood and public venues the captions short yet effective. give at times nostalgic at times political but also sarcastic commentary the third photograph in the album, which you can see here is the first two to pick people a family father mother and daughter alongside two women on the right there and a dog are posing in front of a wooden shelter. while the family are seated for the photograph the two women are st

. >>> we now have new video today obtained by cnn showing the sequence of events led to the death ofack man in police custody. and a warning, some of the images you're about to see are very disturbing. >> okay, okay, okay. okay, okay. oh, lord jesus. >> louisiana state police just released this footage, which includes nine different bodycam and video clips. this happened over two years ago. his family said police told them initially he died on impact in a car crash. i spoke with greene's mother last hour and she told me she's disgusted by this whole situation. >> they have no credibility. they continue to try to shy away from and shine the light on other issues that have nothing to do with my son's murder. i'm disgusted. i just haven't grieved and i haven't even screamed, i haven't cried. and there's no empathy for how they do this to another being and then let the family continue to suffer. >> the case is now a subject of a federal civil rights investigation involving the fbi, department of justice and attorney general's office. joining me right now is retired lapd sergeant cheryl d

the wuhan strain —— covid. this comes from paul monro. paul, this is about genomic sequencing. way we decide what a variance is is by looking at the sequence, it's genetic make what. we have variants of concerned and the indian variant is an adaptation from the wuhan virus, which started in china back in 2020. ., , ., , in 2020. professor hunter was blue i think the thing _ in 2020. professor hunter was blue i think the thing to _ in 2020. professor hunter was blue i think the thing to say _ in 2020. professor hunter was blue i think the thing to say is _ in 2020. professor hunter was blue i think the thing to say is not - think the thing to say is not everyone — think the thing to say is not everyone has _ think the thing to say is not everyone has their - think the thing to say is not everyone has their sample | think the thing to say is not - everyone has their sample sequence. we are _ everyone has their sample sequence. we are only— everyone has their sample sequence. we are only sequencing about 40 to 50% each _ we are only sequencing about 40 to 50% each week of samples,

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investigators are trying to figure out the sequence of events but say the marine corps also collided with the second car. >> the collision happened with the force such that the vehicles came to rest some distance apart. >> reporter: a mother and her daughter were in the second car, both are expected to be okay. neighbors say this accident could have been worse. >> it happened just about time that the school ended. so there were children around. it was just so horrible. >> reporter: there are reports that the man driving the sedan may have suffered a medical condition, but the cause of the crash has not been released. >>> on capitol hill, house republicans are poised to remove liz cheney from her leadership position. the wyoming lawmaker has refused to back former president trump's false claims that the election was stolen. >> remaining silent and ignoring the lie in baldwin's emboldens the liar. i will not participate in that and i will not sit back and watch in silence while others lead our party down a path that abandons the rule of law. >> the vote is expected to happen tomorrow a

. >> if you look at the genomic sequence of the viruses that are in bats in the wild it's strikinglyar to the sequences that you have found noun people who have been infected with the original virus. >> are you confident it develop naturally? >> no, i'm not convinced. i think we should continue to investigate what went on in china until we find out to the best of our ability what happened. >> kayleigh: another 180 from dr. fauci and the media. i want to start with you and a sound bite to what president trump and myself were saying a year ago today. >> have you seen anything at that point that gives you a high degree of confidence that the wu virus was there? >> yes, i have. and i think the world health organization should be ashamed of themselves. >> he said yesterday he has a high degree of confidence the coronavirus originated in a lab in wuhan, china, and get his own intelligence agencies say they're investigating. does the president have information and has drawn the conclusion? >> assessments indicate that the statement is consistent with what some analysts believe is the place

>> so, i think the key here is the set up, the sequencing, just consider these facts from the pandemic low to the september high of last year the stocks index went up 100%, nvidia went up 225 and then that's a six-month run. and then since then, tony referred to it, the last nine months after that huge month nvidia is dead flat whereas the stock has continued up 30. so it's arrested champion. in the corner stone rested champion's basket. after a great run like that, 220% in six months you're entitled to rest which it's done and it's usually the rest that allows you to assert yourself again and break out. >> mike, your take >> yeah, i mean, one of the critical things from a fundamental perspective is when you see a company that's sort of been under performing its peers in recent history as this one has, is there a fundamental reason that might be the case or are their products falling out of favor, certainly not the case for nvidia which has had a number of important new releases many gpu's are impossible to come by so it's a nice and premium product. that's a good thing. that with many

. >> it's issue is the sequence, one of two, we have the strong advance, long with everything, everything coming off the pandemic low then you had that aggressive sell off, right. we hit a high in early march 6780 and draw down $10 a barrel. 15% decline and back to that level. you see the little hats i've drawn on the chart, second and last chart, we're on trend, in order to continue up trend after drawing down 12 to 15% and getting back to the former high, typically before you will get stuck backing away hence we think oil is stuck here for a bit. >> tony, what are your thoughts on this? >> i think this is a great use of selling a call credit spread. especially if you look at the technical reason for it. you have this huge rally over the past five months, you start to see signs of exhaustion with a double top forming, good signs of consolidation what a call credit spread allows you to profit from, even if it stays at this level you are able to profit, you only have losses if rally substantially above this level which will invalidate the technical analysis so i think it's good use of the

and you really have to piece like in the bottle this sequence of events they've been tsunami hit 1st and this made the houses collapsed or where they collapsed because of the earthquake or tsunami from this the what were the people doing why is it that some people died and some people did know. the 2 researches want to determine how the disaster on folded big goal to trace the tsunami back to the events of the tree get the way. his goes to meet survivors in the small fishing town of one. when the wave heat pump do look tif was on his boat 100 meters from the shoal. water and then. get off the boat. very young. when the 1st wave came in there was a big trauma and when i'm on deck and we're going to go up up and you for the tremors on the boat that i hear oh yes the whole boat was rocking i just the water level had dropped and the boat had run aground on what they could do if they stayed with the boat. did you stay on the boat you did up on the dresser. i got held on to the mast yeah ok and then i saw the way of approaching in the distance you jumped up scarlett was very fast so. it rea

virus, meaning look at if any of the laboratories there were working on bad coronavirus to look at the sequencesthe strains, look carefully at the wet markets in terms of people working in the wet markets, people who ate, for example, fried bats or bat soup or bat tea or people cleaning the wet markets. i'd like to say this far and a way the most likely is direct or indirect contact with a bat through the wet markets or otherwise. very unlikely, i think is that it was a lab accident, pleening someone working in a lab with a bad coronavirus and then due to either poor technique or poor isolation of that virus got infected. >> why do you think that -- doctor let me interrupt you. now you think that now we know from the intel community that several researchers amounts wuhan got sick with covid-like symptoms two months before any of the rest of us knew about -- the symptoms or what covid-19 was, doesn't that change your thinking about the origin? >> it doesn't. first of all, we need to know what exactly they were sick with. we don't know for sure that it was covid-19 that they -- that was that infec

technically, leeds united can still finish 7th, but the sequence of events that would have to happenh games — so arsenal have a big chance, with them taking on brighton. i'm just relieved that we also don't have relegation or mutations because that would be the whole show! thank you very much. now, as well as being the last game of the league season, for new champions manchester city, it'll also be the end of an era when club legend sergio aguero plays for them in the premier league game for the final time. the striker has scored 258 goals in his ten years at the club — winning five league titles, one fa cup, six league cups and potentially a champions league title if he plays in the final. but right now, his manager isjust thinking about sunday's game against everton. the impact of this guy and his ten years here, the numbers speakfor himself and the humanity, he's one of the top class players in the world. i would say he has to be incredibly proud. what he has done for this club will remain like a legend. hopefully he can play the last game against everton, and the champions league

across the country so that we _ is a sequence across the country soe know the prevalence is quite low, it's around — the prevalence is quite low, it's around 2%~ _ the prevalence is quite low, it's around 2%. but we do know there are hotspots _ around 2%. but we do know there are hotspots particularly in the north west— hotspots particularly in the north west for— hotspots particularly in the north west for example but we are also starting _ west for example but we are also starting to — west for example but we are also starting to see it gather pace in the south—east. that is the concern, that this _ the south—east. that is the concern, that this virus — the south—east. that is the concern, that this virus will start to spread more _ that this virus will start to spread more widely. but the reality is, it's probably in lots of different places— it's probably in lots of different places at— it's probably in lots of different places at the moment at low prevalence and we have not yet picked — prevalence and we have not yet picked uu _ prevalence and we

if i run the sequence on through the weekend and into the start of next week dominated by low pressure remaining around orjust below the seasonal average. notjust for the weekend, but even as we head throughout much of next week. this is bbc news, the headlines. an israeli air strike has destroyed an apartment block in gaza city as the unrest intensifies — residents had been warned to get out. as rockets reached a suburb of tel aviv — benjamin netanhayu said the palestinians would pay a heavy price. some 30 people, israelis and palestinians, have been killed. seven school children and two adults have been killed in a shooting at a school in the russian city of kazan. security forces stormed the school and detained the suspected attacker — a nineteen year old former pupil. in the us, there have been long lines at petrol stations, as some drivers have been panic—buying fuel in case prices rise in the days ahead. it's a knock—on effect of last week's cyber attack on a major us fuel pipeline — the colonial pipeline says it hopes to have substantial operations back under way by the end of t

if i run the sequence on through the weekend and into the start of next week dominated by low pressurenal average. notjust for the weekend, but even as we head throughout much of next week. this is bbc news, the headlines: air strikes have been launched on gaza as unrest escalates into the worst violence between israel and the palestinians in seven years. more than 30 people have been killed. the united nations has warned the conflict is moving towards full—scale war. earlier, an israeli airstrike destroyed an apartment block in gaza city. residents had been warned to get out. with hamas rockets reaching a suburb of tel aviv, israeli prime minister benjamin netanhayu said they would pay a heavy price. seven school children and two adults have been killed in a shooting at a school in the russian city of kazan. security forces stormed the school and detained the suspected attacker — a 19—year—old former pupil — he'd been carrying an automatic weapon and was wearing an explosives vest. now on bbc news, hardtalk.

if i run the sequence on through the weekend and into the start of next week dominated by low pressureers. and this temperatures remaining around orjust below the seasonal average. notjust for the weekend, but even as we head throughout much of next week. welcome to bbc news. i'm david eades. our top stories: rockets over gaza through the night as unrest escalates into the worst violence between israel and the palestinians in seven years — more than thirty people have been killed. explosion this was the moment earlier that an israeli airstrike destroyed an apartment block in gaza. missiles also reached a suburb of tel aviv. prime minsiter benjamin netanhayu says palestinian militants will "pay a heavy price". a teenage gunman in russia opens fire at a school, killing at least seven children and two adults. relatives of ten people killed in belfast in 1971, win a fifty—year legal fight to clear their names. we've got an audience, we've got dancers,

martin: i think the euro is basically sequencing. we spent a lot of time in january and february about how bad europe was getting the vaccine ready. the vaccine is getting a dramatic acceleration across the eu, 27 countries. we see european bonds yields rising much faster than what we have seen in the u.s. over the last four weeks we are seeing the currency solid. it is a relative basis we are saying that european situation, and recovery funds will kick in in july. the european union must get tourism back because it contributes 23% of the european economy on gdp terms. draghi said they will not wait for a european passport. it is an italian passport, and we were prefer people to travel to italy to boost tourism from the middle of may, a few weeks time. that is an aggressive push to get tourism and tourist season in the summer pushed ahead. manus: then you look at other countries about to go into a rolling curtailment again on the back of the reopening. thank you for being with us this morning, martin malone, chief economic advisor, ap

. >> carter, how are the charts looking like >> well, the issue is the sequence, right? them one of two we have that strong advance, along with everything. everything is strong coming off the pandemic low then you have that aggressive selloff, right we hit a high in early march of i guess it's $67.80, then we draw down $10 a barrel, 15% decline. we've gone back to those levels. you can see the hats i've drawn on the chart second and last chart. so we're on trend, but in order to continue an up trend after drawing down 15, 12, 10% and then getting back to the former high, typically before you exceed it you contend with it. hence, we think oil is stuck here for a bit. >> tony, what are your thoughts on this? >> i think this is a great use of a -- selling a call credit spread, especially if you look at the technical reason for it you have this huge rally over the past five months you start to see signs of exhaustion you have this double top forming. those are usually great signs of a potential consolidation. that's exactly what a call credit spread allows you to profit from.