meg tirrell now with the top story at the bottom of the hour. what did moderna say about its vaccines, specifically >> they called it a remarkable achievement, panel of expert advisers to the fda. led to both moderna and pfizer's vaccines getting to the public less than a year after the work began on them. the vote was 20-0 in favor with one abstention, that the scientific evidence for those 18 and older. there was discussion about potential for allergic reactions after a small number were seen following pfizer's growth. moderna noted that their ingredients aren't identical to those in pfizer's so it's not clear it will have that effect but it's something that the fda will pay attention to. if the regulator issues emergency use authorize ace, a panel will weigh in on that allergy issue over the weekend and next week almost 6 million doses are expected to go out across the u.s. along, of course, with 2 million doses of pfizer's shots shep >> some states are being told their allocations of pfizer's vaccine have been cut by 30 to 40%. is that true

meg tirrell has details for us how is this all going? >> reporter: they've finally reached this deal with pfizer. we've been hearing this back and forth with pfizer and the u.s. government around securing a second 100 million doses of pfizer/bi ontech vaccine delivering 70 million by the end of june, 30 million coming by the end of july. same as they paid for the first 100 million doses, almost $2 billion. this adds to our supply of approved or authorized covid-19 vaccines we ordered 200 from moderna as well operation warp speed has set very aggressive target force rolling out the vaccines they said 21 million people should get their first dose in december, another in january and 50 million in february, guys we're starting to see timelines shift a little bit if you look at the update we just got from the cdc about how many doses have been distributed we're at 9.5 million distributed, 1 million administered so far. there's an operation warp speed meeting coming up in less than 30 minutes and bound to be questions about the pace of vaccina

meg tirrell has the latest on a big week for vaccine news. the other big theme for us a couple of high-profile ipos. leslie picker has the latest for us on airbnb mike over to you. >> market starting the week a little bit heavy footed after about a five-week upward sprint that took the s&p up 1%. look at the year to date, really extending this rally you might look at this and say incredibly modest pullback supported by some of the big growth stocks getting a bid. what would it mean to have just what would be called a routine pullback what has been the pattern? the pattern has been when we have gotten a pullback it has gone back to the prior ceiling that becomes the floor if you look back over here, this is how the market has stare stepped up you can talk about going down into the 3,500s on the s&p before you can call it a pullback that's the range 5% down is 2,500 a lot of folks looking at that area would feel worse than it would look on the chart. look at bonds they have been associative for stocks corporate bond eps beth high yield and high

our meg tirrell with the late for us. >> in the first wave pfizer is shipping nearly 3 million dosesf covid-19 vaccine across the country. the vaccine is the fastest ever to be developed and walgreens has been moving just as quickly to prepare for this historic day. joining us now is wall green's group vice president of pharmacy operations and services. it's great to have you here. what happens at walgreens today? >> thank you so much for having me. really appreciate the opportunity. we have been similar to how it's been for the last couple of months. we have been actively preparing for this moment for when vaccine is available, so we have all of our teams ready to go so that when vaccine does come to our locations we can go ahead to kt at rate is our plan to support the health care workers and the activating the long-term care facility plans next week as they move forward. >> so just to be clear, when i think of wall green, i think of the general public, and it's my understanding that we aren't going to have access to this for months. are you guys playing a role in the rollout to fr

first, cnbc's meg tirrell. meg, how significant will it be to have not one, but two vaccines out there >> well, shep, it's a scientific feat that has never been accomplished before in history work only began on these vaccines in mid-january when the genetic sequence of this new virus was published. now not one, but two vaccines have shattered every record for the pace of development. >> when this is over, which it will be over, we're going to look back and say it was science that got us out of this, pure science. >> now, after the fda's decision, an advisory group to the cdc meets this weekend to vote on whether to recommend moderna's vaccine. with its supply combined with pfizer's, as many as 20 million americans could receive their first shot by the end of the year that would almost cover everyone in the top priority groups, health care workers and residents of long-term care facilities that same cdc group will also vote this weekend on who should be next in line. one framework that's discussed would give pri

meg, thank you so much, our meg tirrell. ty? >> as we mentioned, the fda is set to review moderna's vaccine later this week. for more on the vaccine pipeline, michael, it's always good to see you and great to have you here on this rather historic day. i guess first question is when all is said and done and all of the vaccines from moderna and j & j and astrazeneca get coming to us, is supply going to match ultimately demand in 2021? >> that's great questioning. good to be here with you, tyler. i guess one question is what do you think the demand will be? we actually did a survey and there's been a number of surveys out there suggesting that 50 to 70% of the american population wants to get one over the next year. if you do the math between moderna and pfizer, as well those coming with data in january, the numbers do clearly suggest there will be capacity to make that demand and that's why we're optimist being 20-21 will play out just fine. >> will there be capacity globally to meet demand? >> there will be capacity to meet globa

our meg tirrell on pfizer's historic day today. >>> the m&a announced change is all around us. shaped by technology and human ingenuity, we can make it work for you and your business. ♪ help the world believe in holiday magic.thing and this year was harder than ever. and yet, somehow, you all found a way to pull it off. it's not about the toys or the ornaments but about coming together. santa, santa, you're on mute! just wanted to say thanks. thanks for believing. >>> as we have been saying, a fizz busy day. a plethora of deals. the biggest announced on saturday the giant pharma deal $30 billion which is what it was worth when it was announced. astrazeneca's stock price might not be quite worth that but you can see shares of alexion are up and entering a definitive agreement in which astrazeneca will be buying alexi ooon. american depository shares and, again, we will keep an eye on those because they did appear to be down as much as 6%. no real overlap between these two companies. i'm told by the way that they did begin speaking in the summer. let's call it late summer of this

meg tirrell with the latest on those efforts. >> this morning we got the fda briefing document on moderna's vaccines and we're going through the same process with moderna that we went through last week with pfizer and biontech overall the fda saying the efficacy, of course, is strong at 15% of moderna's advantages own and protecting it against covid-19 disease also detailing the safety of the vaccine. things like injection site reactions, fatigue, headache, muscle and joint pain known as reactogenicity, chills, after the shot rare events, swelling in the vaccination arm as well as bell's pales which is a temporary paralysis or seizing up of the face, three on vaccine and one on placebo not clear if that's related to the vaccine but something they are looking at with pfizer's shot as well importantly no allergic reactions they saw here in the data as something that's being looked at with the pfizer vaccine and that will be a key topic of conversation this week. on efficacy, we also got to see this great graph showing protection even after the first doze really at day 14, two weeks after you

the for more -- spike, you should say for more let's welcome in our own meg tirrell and meg i'll start off with you will more people get the moderna vaccine in this country or the pfizer vaccine in this country >> well, as of right now the supply deals that we've struck, the u.s. has bought 200 million doses of moderna's vaccines and 100 million dose of pfizer's vaccines we know they are working on a deal for an additional 100 million doe million dozes of the pfizer vaccine and we'll have to see how that shakes out. we should have equal availability of the vaccine and every single doze we hope gets used >> when we add 2,900 million, we get to 300 million but is that enough for 350 million people to be inoculated because it's a two-dose protocol? >> yes, exactly. you know, there are more vaccines that are being tested and developed, of course, from johnson & johnson, and we might get to see their data in january. that's a single-doze vaccine so that would mean more supply right off the bat. astrazeneca and novavax behind that the government do have options to order more from pfizer and

meg tirrell with cnbc. dr. slaoui, i wonder if you could go back to those allocation numbers per month? i want to make sure we got it right. 40 million doses in december, 60 million in january? with only half the doses being sent out and the second half being followed up to ensure proper storage, what is the right way for us to talk about the number of people who will get their first shot with these doses? you know, in the first 6.4 million, is that 6.4 million people getting their first shots? we often decide by two and say it's enough for 2.3 million people. what is the right terminology for us to be using? >> thank you, meg, for the question. i used the number of people to be vaccinated with a complete dose of vaccine, so two shots. 20 million in december, 30 million in january, 50 million in february, and that's with the pfizer and moderna vaccine. there is a chance that we may have more vaccine doses available in february, particularly with the unsen vaccine if it gets emergency approved. so it's possible

thank you, meg tirrell. >>> the cdc estimates the united states could see as many as, listen to this, 23,000 new covid hospitalizations a day during the week after christmas that's six times the 4,000 we're averaging right now. yesterday more than 104,000 americans were in hospitals sick with covid that's another all-time high according to the covid tracking project. some health experts say we're right now starting to see the very first signs of that thanksgiving surge everyone talked about but hospitals cannot take much more in some regions across our land they're maxed out already. more than a third of all americans live in areas where icu beds are nearing capacity. that's according to a "new york times" analysis of new data from the department of health and human services nbc's jay gray is covering the surge. jay. >> reporter: hey there, 14e7 the entire country is in essence a hot spot right now tonight in tarrant county to the west, that's the ft. white side of dallas, there are only 18 icu bed as valuable right now, a situation the health director there describes as grim and one

always appreciate it meg tirrell for us pfizer up 3% and biontech as well is this a sell the news kind of event for vaccines names with big runs joining me is a senior analyst at bernstein ronny, great to have you back. are you recommending that people take some profits here >> so, what i'm basically saying is that what it looks like more than anything else is we have an earlier wave of vaccinations in the united states. most people think it will be around mid-year and it now looks that we've had a significant amount of vaccination in the first quarter and once you pass roughly 50%, we can see the epidemic plummet so the argument is that the stock that they should perform on thisnews are the stock that are part of the reopening trades so like the hotels, airlines and my colleagues just upgraded this morning. less so if the drug companies which are probably more funds for the trade. the stocks are seeing a little bit of pressure from the nominees that the biden administration is putting out. becerra for hhs is not known as a friend of the drug while the vaccine has been brought to the m

meg tirrell, tell us the truth well, hey, andrew. really explaining a change that happened between september and november for 2020 supply of its covid-19 vaccine as recently as september they were forecasting 140 million doses could be available this year, and then as of november, they reduced that to 50 million doses. they're still projecting 1.3 billion doses being available globally explaining it was an issue with their raw materials but pfizer saying it's confident in its ability to ship, you know, 50 million in 2020, and 1.3 billion in 2021. similarly, moncef slaoui from operation warp speed telling us there's no change to pfizer's commitment and he hasn't been informed of issues this isn't a current problem but explaining something that happened at least a month ago. now, we are a week away from potentially seeing the first doses going out in the united states, depending on how quickly the fda acts, and operation warp speed has said that the initial doses available from pfizer in the first batch will be 6.4 million. and guys, t

our meg tirrell.oming up with the airbnb ipo taking the spotlight, we will hear from the ceo from booking.com, what he says is its biggest advantage over airbnb. the stock indicated to open at $150 right now after pricing at $68. >>> bank of america says there are potential headwinds ahead are to the red hot home builders why and who's in worst position going forward. back ia upn cole >>> welcome back to the exchange bank of america's latest covid housing impact survey shows that suburban exodus may be something of an urban legend john, where we are, it's been blowing up with demand i take your point. our robert frank has about new leases in manhattan having the strongest november in 12 years tell us what you think is going on here. >> thank you for having me we ran a survey for about six months first three months of the survey there was very little differential between urban dwellers and suburban dwellers in terms of their responses. most really didn't cite a desire to move because of covid it was ar

meg tirrell, thank you. >>> the uk received its first batch of pfizer's vaccine today. the doses arriving on trucks from the company's factory in belgium. now they're being stored at a secret location in the uk. the country's business secretary says people should feel confident point vaccine. >> we'll have 800,000 of these doses available by the start of next week and we're on course for that >> that from the bbc people working in long-term care facilities will be in line first after that health care workers and people over the age of 80. the first round expected to cover only a fraction of that country's top priority groups. >>> without more covid relief, our nation's 911 emergency medical system will collapse that's the message from the ambulance association. in a letter to the department of health and human service, the association wrote that ambulance companies across the country are at their breaking point now. and hhs spokesperson said the agency gave them another $20 billion in aid last month. but ems services warned it's still not enough to keep them afloat nbc'

we appreciate it meg tirrell.cine around the corner either way, how will we distribute it once it hits the broader population grocery and drug stores think they will have a big role to play and joining me to discuss that is the evp of pharmacy and fuel operations at food city parent kvat foods. mickey, it's good to have you. first of all, are you targeting your involvement to be in these early weeks or once there's many more doses available to the broad population >> well, first of all, thank you for having me. we've literally prepared ourselves to be ready for whatever role we need to play. we're ready to go with the federal allocation when it rolls out, and we've also offered our services to the states should they deem that they need to count on us to help in that population as well. >> what advantages does a grocery store offer in this distribution process, because i've read, for example, you have wide and long store aisles where you can safely distance people as they wait and that kind thing, but we spoke to t

meg tirrell is here on how the country got a head start meg? >> reporter: they shower did, kelly. this is a world first, the first covid-19 vaccine being cleared by a government or completing phase three clinical trials. so as you said these doses will start to go out in the uk next week we're hearing about 800,000 doses in that first shipment that's of a total 40 million that pfizer and biontech have agreed to supply to the uk this year and next year operation warp speed here in the u.s. is holding a briefing right now, and the chief adviser to that effort was talking about this uk approval process really saying this is a gold standard agency who reviewed this and making a comment about how he hopes americans will take this clearance. here's what he said. >> they have not been part or involved in any of the politicization that surrounded the development of this vaccine, and i hope this will be another evidence for the american population that the data with these vaccines are clear, are transparent and demonstrate that they are effective and safe for use in the general population.

meg tirrell with a closer look at the regulatory process. meg? >> sara, we could just be hours away from the second vote from an advisory committee to the fda supporting authorization of a covid-19 vaccine they are currently in discussions now. they have done presentations from the fda this morning on the company's data the company has presented. they are taking questions from the committee. and that voting is expected to happen sometime between 3:15 and 5:15 we will bring the results of that vote. last week the same panel met on the pfizer/biontech vaccine and they were talking at least in terms of any dissent about the age involved there, 16-plus for that emergency use authorization. for moderna it is 18 plus. we don't except that to bea hiccup if they vote this afternoon, the fda could issue its emergency use authorization tomorrow or saturday then doses would go out across the united states on top of the pfizer/biontech vaccine that started going out this week. some of the conversation among the panel members today include the alernlic reacti

. >>> let's turn now to the latest on the vaccine front and operation warp speed meg tirrell has the latest. >> reporter: we got a briefing from operation warp speed now and got a sense of the pace and next week's allocations are going to be 2.67 million from pfizer and moderna and the 2.9 million that went out the week before that gets us to 15.5 million doses in december and the rest of that is going to be pushed into the first week of january that is a bit of a lag from what we were expecting for the 20 million doses, both getting out in december and getting those first shots into people's arms that is going a little bit more slowly than the government had expected so we're going to keep watching this closely hoping, of course, that the pace of being able to administer the vaccines starts to pick up we got updates on the development front for vaccines for johnson & johnson which is the next one where we get data in january, that's one shot. they could potentially if that data is good file for emergency use authorization in late january, early february. astrazeneca has enrolled 27,

meg tirrell has got the latest details for us into here in the u.s.ig day, the fda released its briefing documents are pfizer and biontech's vaccine ahead of a meeting on thursday we heard what the regulator had to say about the safety and efficacy of the factionine no specific safety concerns identified that would preclude issuance of emergency use authorization. in terms of the efficacy, showing even after one dose the vaccine does provide some protection we have a graph here that shows the difference between the placebo arm and the vaccine arm. after one shot, 14 days later, you can see that the vaccine is protective i am not sure we have that graph there. but you can see some of the other side effects that you have in terms of this week, the fda outside commission meets on thursday to discuss the vaccine. after that the fda will vote cdc's advisors meet friday and sunday to potentially recommend this specific vaccine. all of this is coming up fast. moderna's meeting is next thursday we will do it all again next week this of course as the first pat

anthony fauci, operation warp speed's monsef slaoui and meg tirrell.nd family safe during the holiday season you can register at cnbcevents.com to see it all becky? >> thanks, andrew. >>> when we come back liontree founder and ceoaryeh bourkoff will join us his outlook for m&a. >>> let's take a quick look at the markets. after gains, you're seeing green arrows dow up by 300 points s&p up by about 10 points and the nasdaq after setting a record indicated up anhe26otr this morning "squawk box" will be right back. in a land not so far away, people are saving hundreds on the most reliable network with xfinity mobile. they can choose from the latest phones or bring their own. and choose the data option that's right for them. they even get nationwide 5g at no extra cost. and since they are on the carrier rated #1 in customer satisfation, they live happily ever after. again, again! xfinity mobile. your wireless. your rules. your way to stay closer together. click, call, or visit an xfinity store today. >>> aryeh, it's great to see you. now you do it on zoom v

breaking news on moderna meg tirrell has got it for us. hey, meg >> hey, wilf well, the u.s.on to purchase an additional 100 million doses of moderna's covid-19 vaccine for delivery in the second quarter of next year now of course the government had already purchased 100 million doses. moderna says that 20 million of those doses will be delivered by the end of december, 2020, as expected the balance will be delivered in the first quarter of 2021. and then this additional 100 million doses would come in the second quarter by june of 2021 of course all of this contingent on this vaccine getting emergency use authorization from the fda, which could come after its meeting on thursday of next week guys, of course the context of this is the stories that have been swirling about pfizer having offered its second quarter allotment of its vaccine to the u.s. government before then selling it to other governments and concern that we would reach a gap in availability of vaccine next year so the government striking this deal with moderna now saying that they are assured these 100 million

meg tirrell did a great job of describing the data coming out on the moderna vaccine, some encouragingesults of the vaccine preventing the asymptomatic spread of the virus. we know that the trials have been focused on determining the efficacy of both the pfizer and moderna vaccines and preventing people from developing symptoms and getting sick but we don't know that it prevents them from harboring the virus, so those are studies that are going to need to continue moving forward, so that we can answer that important question over the course of time. >> -- among your staff and those who you are polling to taking the vaccine or uniformly is everybody saying bring it on >> you know, i don't know yet how many people are going to wish to receive the vaccine on the initial distribution, that's one purpose of the questionnaire that we've been handing out to people i mean, the majority of people will want to take advantage, but there will be some that will wish to wait and that will be fine they will not be deprioritized or in any way discriminated against if people don't want to participate i

meg tirrell is digging into that in more detail and will join us shortly.uch of that is a fresh update versus a headline nonetheless clearly moving the market as you can see there from the russell 2000 shot. mike santoli, despite that, as you discussed earlier we have brecken out of the recent range having sort of treaded water for a while. encouraging to see positivity at this stage of the rally when people have been saying it is time to take a profit? >> it is seasonal strength is persistent. that usually is tough to fight that's been the rule so far in this yonge month i will say the negative response to this headline, it just shows that you the market was stretched a lint tight and entirely fixated on things getting better like a light switch next year as opposed to worry being what's going on right now. so this is just one of those things whereas i was saying in some of my notes this morning, all it means when sentiment is really extreme is that it lowers the threshold for the kind of surprise that can cause a little bit of a shakeout. that's what we s

. >> the police probably the first week investigating tirrell's background to see what type of kid heang-related. they came back and they said we can't find anything. >> they took a week to find out his character. a perception when a black man is shot is always gang related. my son wasn't in a gang. wasn't on drugs. he was in college. he was very active. then next thing you know he's dead. >> "this is life" with lisa ling airs at 10:00 p.m. tomorrow night right here on cnn. needles. essential for sewing, but maybe not for people with certain inflammatory conditions. because there are options. like an "unjection™". xeljanz. the first and only pill of its kind that treats moderate to severe rheumatoid arthritis, psoriatic arthritis, or moderate to severe ulcerative colitis when other medicines have not helped enough. xeljanz can lower your ability to fight infections. before and during treatment, your doctor should check for infections, like tb and do blood tests. tell your doctor if you've had hepatitis b or c, have flu-like symptoms, or are prone to infections. serious, sometimes fata

meg tirrell on the pfizer vaccine development today. >>> we're going to watch the finalization of this stimulus package as the president last night posts a video on twitter blasting that relief bill, saying the direct payments don't go far enough, called it a disgrace he stopped short of saying he would veto it. take a listen. >> the bill they are now planning to send back to my desk is much different than anticipated. it really is a disgrace. i am asking congress to amend this bill and increase the ridiculously low $600 to $2,000 or $4,000 for a couple i'm also asking congress to immediately get rid of the wasteful and unnecessary items from this legislation. and to send me a suitable bill or else the next administration will have to deliver a covid relief package and maybe that administration will be me. >> in response to the comments, house democrats say they're going to try to work on a stand alone bill for those direct paymentsunder unanimous consent, but that's a high bar given that any single member can kill it. mike, as for the political ramifications, what does it say about th

authorization applications and pfizer releasing data with the fda on review of its covid-19 vaccine meg tirrelldigging through what has been a substantial report and has the latest for us. meg? >> hey, morgan these were highly anticipated documents because it's the first time we're seeing the fda really weigh in with its own analysis of the pfizer beontech vaccine trial results. what we deemed before was the top line it worked 95% at preventing people from getting covid-19 we knew it generally appeared to be safe, though it does have some side effects, especially on the second dose that could make you feel pretty crummy the next day. now we are seeing the detailed data and how the fda is think about this ahead of the meeting thursday on safety, this is important, the fda is saying "the trial data suggests a favorable safety profile with no specific safety concerns identified that would preclude issuance of an emergency use authorization. now they are also laying out which questions they will pose to this question of advisers on thursday, is it reasonable to believe the pfizer and biontech vacci

. >> thank you for that is correct meg tirrell. >> kelly >> for more now on what we can expect from this meeting and from the pfizer vaccine in general, dr general. it's great to have you here. one of the questions that comes up when i talk to friends and neighbors and they say you go through the fact over the past couple of months you but what happens if it causes problems over ten, 20 years and it takes a while to show up, what would you tell people about that concern in. >> you have to really compare and contrast the value of preventing covid-19 versus potential adverse effects. we know that the studies were well conducted and in a fastidious manner. there are some adverse effects that are deemed minor. but long-term consequences on unknown, much like many vaccines that are initiated you don't have years and years of experience. you have to go with what you have there will be by the time these are released tens of thousands patient years experience, so we hope there are no long-term consequences and we can rely on previous vaccines and the adverse effects associated with them to give

up more than 65% from its ipo price of 102 and we're waiting pfizer and biontech let's get to meg tirrell for more on that story hi, meg. >> hi, kelly while we are expecting the fda to issue emergency use authorization, really at any point now after this positive vote from its advisory committee last night, here's the timeline of what we're looking for in the coming days. so the fda is working now essentially on that emergency use authorization. today and over the weekend an outside group of advisers to the cdc is meeting to discuss the vaccine and will vote to give its recommendation for that specific vaccine after the fda gives its green light and then within 24 hours of that emergency use authorization, it expected that 3 million doses are going to start to ship across the u.s how do we know the fda will act sunday with this eua it put out an unusual statement this morning saying it's informed pfizer that it will rapidly work toward finalization andish you issuance of an emerge authorization. yesterday the vote was 17 votes in favor, four votes again and one vote -- one person who abst

joined by tony meyer as new york city shuts down indoor dining we have 59 minutes left in trade, meg tirrell has information with information surrounding moderna's vaccine and the fda approval and bop bop is tracking the market meg let's start with you. >> we got the briefing documents from the fda how it is looking at moderna's covid-19 vaccine ahead of that meeting of its outside advisers on thursday essentially laying out what we though about the safety and efficacy of this vaccine 95% protection against covid-19 disease also showing that that protection starts to come after 14 days this ahead of that thursday fda advisory committee meeting where we will hear all of this discuss asked their vote at the end of the day on whether to recommend authorization of this vaccine. it could come, if it follows the same pattern as last week, on friday then 6 million dose ofs of moderna's vaccine will head out next week to more than 3,000 locations. i wanted to provide an update on the antibody drug front as well. we learned today from operation warp speed's doctor slaoui even though they are shipping

that was the major reason for the dow's deficit and the futures that it has climbed back from meg tirrell has information on the mutation and everything coronavirus. >> we are hearing about the new strain of the coronavirus reported primarily in the uk being attributed there by government officials for some of the increased traps mission we are seeing if you look at the numbers of new daily cases in the uk over the past month in particular, it is dramatic. check out the cratering after they had a lockdown for most of november then the spike back up this the cases once they lifted it. they are saying some of it could be attributed to human beaver. as dr. fauci says, once you lift lockdowns some people let it rip. human behavior could be contributing but also that the new variant detected is more transmissible. the question, do the existing trugs for the coronavirus and our vaccines work against this strain eli lilly, who makes the antibody drugs say they should still cover it they say their drug should maintain full activity against the new strain, regeneron believes the cocktail will be e

developing stories this morning, use ylan mui has the ls out of washington, but we begin with meg tirrell who has ready-made stories almost every day. we knew the advisory panel was meeting yesterday. i guess because there was no 16, 17-year-old issues, they got almost unanimous except for an abstention >> yes, that one person who abstained essentially thought that instead of emergency use authorization, the vaccine should be given expanded access, which really is just more limited way of making it available in his opinion to more high risk groups but really endorsement across the board from this anel no debates about the efficacy. and comments from the chair of this committee that this vote shouldn't be compared with pfizer's in any way because of course pfizer's vote included the 16 and 17-year-olds. and that was really the issue. so the fda putting out a statement last night saying that it has informed moderna that it will rapidly work toward finalization and it also notified "operation warp speed" so they can execute their plans. and this is the same time we got friday morning on pfiz

meg tirrell has the latest developments meg, like joe said, there is a lot to analyze here. >> thereis i mean this was a nine hour long meeting with finally that vote at the end of the day. ultimately it did come down to 17 yes votes, four no votes, one abstention off weoverwhelmingly positive. normally they explain their votes, but this one had run so long that they ended it abruptly and some sxwres xpressed frustrn because they couldn't explain their vote and this is the last step before the fda needs to make their decision and so at least for two of the panelists, it was about the question that was asked. essentially do the benefits of the pfizer/biontech vaccine outweigh risks for individuals 16 years or older. and it was the age question. dr. david kim from the department of health and human services who is one of the no votes told us, i would have voted yes most enthusiastically had the language been 18 years of age and older one of the questions really was pfizer had extended it down in the trial after it started the trial. and so there was debate about whether there were enou

meg tirrell has a look at the process, how it is going so far. >> reporter: we have been seeing the first health care workers in the united states getting the first shots with their covid-19 vaccine all across the country today from new york to ohio, philadelphia, iowa, and louisiana. all in, 2.9 million total doses going out from pfizer. today there will be a total of 145 locations expected to receive shipments of the vaccine. we learned as of 11:30 during an operation warp speed briefing 55 had already received those. all should get them today by 2:00 p.m. local time. now, we are also expecting of course this week to see moderna's vaccine go through this same process. together operation warp speed and health secretary azar say 30 million people by the end of january will be vaccinated and throughout february and march, 100 million people will have received at least their first dose. this as the government has struck a deal for now consume lative 200 million doses of moderna's vaccine, still only 100 million doses of fizers. in talks we heard from pfizer's ceo in morning for another 100

now headlines on astrazeneca let's get to meg tirrell hey, meg. >> astrazeneca results that are comingut now are the data from two weeks ago, pooled efficacy of 70% for the astrazen emeca when, of course, it's 90% in one arm and 62% efficacy in the other arm. it's interesting to see that vaccine work its way through the regulatory process around the world as they're starting to submit to regulators here in the united states. folks from operation warp speed say those data are not sufficient for fda approval. of course, he's not the fda so we'll have to see what the fda does essentially the data we saw two weeks ago from oxford and astrazeneca. pfizer, we got a new set of data released ahead of a meeting of advisers on thursday this is the first time we're hearing the fda weigh in with their thoughts on those results. importantly on safety, the fda says that the results it saw suggest a favorable safety profile with no specific safety concerns identified that would preclude issuance of an emergency use authorization. side effects you may feel after you get your shots there are two, and p

could approve it this way mig tirrell has the latest. >> a key milestone in the process today to potentially clear this vaccine we got the briefing docks from the fda showing us how the regulator is looking at all the data they say all of the data suggest a favorable safety profile with this vaccine with no specific concerned identified that would preclude issuance of an emergency use authorization. they did see things like injection site reactions, fatigue, headache, muscle pain, chills, joint pain and fever after especially the second shot so folks should know they might not feel well after getting the shot but those are seen often in vaccines they noted four cases of bells palsy in the vaccine group and zero in the placebo. it's temporary weakness or paralysis. the fda said that should be under surveillance as these are rolled out on efficacy, we know it's 95 effective in preventing cases of covid-19 after two doses this graphic shows after one dose you start to get protection from the vaccine at day 14, two weeks after you get your shot. the orange line there is the rate of covid-19 for

let's go to meg tirrell for who will be first in line to be vaccinated meg?> john, this is a really big day. the cdc advisory committee is going to take its first official vote this afternoon for who is going to be at the tippy top of the list once they are cleared by the fda this is an outside group of advisers this began just now at 2:00 and they're going to be discussing this allocation and these priorities until just before 5:00 when they are going to take that vote. really this is phase 1a, just who will get those first doses of course at the beginning, supply of these vaccines will be incredibly limited the first shipment of pfizer's vaccine will be 6.4 million doses. and pfizer and moderna's together will have enough doses for 20 million in december and 25 to 30 million per month starting next year for that reason they have to choose who is at the top of the list the cdc has laid out essentially four groups who are really priorities for them. in that is of course health care personnel. there are 21 million americans in that group. adults over 65, there

. >> thank you very much let's get to meg tirrell she has breaking news on pfizer. meg? >> hi, scott a state just coming out from pfizer about its covid-19 production they're saying they are trying to address public comments that allege there are issues of production and distribution of the company's vaccine. saying, quote, feis ser not having any issues with our vaccine, no shipments are on homemade or delayed. they say we have millions more doses sitting in our warehouse but have not received any additional instructions for doses. we've been hearing from states that their allotments may have been cut, four states saying 30%. florida's governor ron desantis said their next shipment is on hold and pfizer said they have no shipment issues if moderna's gets authorized, 5.9 million doses will go out next week. we've been hearing there should be enough vaccine for 20 million people within december operation warp speed has put that out there and an hes spokesperson tells me that is still the plan florida saying it's because of production issues and pfizer says that is not the

mag meg tirrell, what can we expect for tomorrow >> this group's job is to decide who needs protection the most and that's because supply will be so limited to start 6.4 million doses will be in the first shipment more will go out weekly with two doses each for the end of the year the cdc highlighted these groups as top priorities but there won't be enough vaccine for them all right away and tomorrow they'll vote on phase 1a should it be health care workers, the front line against the pandemic or elderly, especially those in nursing homes who are most vulnerable? and where to essential works fit? those who keep our supermarkets running, deliver our mail and packages these are the questions that they will grapple will tomorrow. dr. robert redfield then decides whether to accept it and directors usually do and then it's up to the state to incorporate the viadvice into their own priorities. >> airlines are getting involved in the distribution. vaccine. american giving nbc a look at the cargo containers they plan to use to carry the doses. they are practicing their flights to test the proc