and because of the genetic risk for type deacons type 1 dalia visas well characterized we can identify those at risk and follow this. this has allowed us to embark on bold, longer-term systematic studies to identify these environmental factors. this study has enrolled over 8600 newborns with high genetic risks for the disease, and we plan to follow them for 15 years. we will be collecting biological samples and information about their lives, identification comfortable, of an infectious agent that triggers this auto immunity could lead to a vaccine to protect against this disorder. .. is conducting trials of promising therapies in newly diagnosed patients. now, the third handoff continues along a spectrum of disease progression and this next age of disease research shown in green focus is on people with established type one diabetes. and a high priority for this stage is a development of new tools and technologies to help people improve their blood glucose control because they can reduce diabetes complications by up to 70%. this is certainly an artificial pancreas that automatically lin

one of the things in the manual is the type of plan check of the type of systems that are installed, due to the fact that we have properties that are one on top of another. planchette is one of the important things to have done tree will save contractors, homeowners money and time before they obtained a permit or start to do any type of work, so they know they can do these systems. we're looking to make this as safe as possible. the water going from a gray water system, unfortunately to a neighbor's property to the top of ground you have or the type of layout you might have done. we like to know exactly what is coming forward and make it easier for the applicant, so they know exactly what they are getting into. we would be able to identify these types of projects, so we have been working with them, for like a said, over two years. i have been with gray water for four or five years now knowing that it is coming forward. one of the biggest concerns we have as well is the types of systems. where they are putting it, how they are putting it. we want to be there for the health and safety

and because of the genetic risk for type deacons type 1 dalia visas well characterized we can identify those at risk and follow this. this has allowed us to embark on bold, longer-term systematic studies to identify these environmental factors. this study has enrolled over 8600 newborns with high genetic risks for the disease, and we plan to follow them for 15 years. we will be collecting biological samples and information about their lives, identification comfortable, of an infectious agent that triggers this auto immunity could lead to a vaccine to protect against this disorder. .. today blood tests can accurately identified relatives of people with diabetes who are at higher moderate risk of developing the disease within five years. this important advance in a bold type i diabetes to launch clinical trials of promising prevention strategies to stop the auto immune attack. it's also important to identify ways to halt or reverse disease progression soon after to preserve any remaining data pells and collaboration with th immune tolerance network trial net is also conducting trials od

there are several foundation types in san francisco. the one that was used in the 1800's was called a wood grillage. they would chop down trees and it would lay lincoln logs, same principle, make the excavation, and they would lay lincoln logs and build what is called a redwood grillage. fortunately, the termites cannot attack at and it lasts hundreds of years. >> is resistant to decay. >> the second most common foundation, as we move forward, the cement can along. >> all the homes, all the buildings rest on just a typical spread type footing. the spread type flooding takes the load, comes down, and spreads it out over a larger area. that is why it is called spread footing. as the soil types get more and more difficult, we start looking at social foundations that may still be spread. a spread type foundation such as a mac. -- such as a mat. it is a blob of concrete that is the enough so that if it tries to move, it moves as a unit as opposed to individual footings. eventually, as you move closer and closer to the shoreline, where you ca

it is that type of thing and that type of research being done. eventually, more research will be done to treat this dreadful disease. host: can you give an example of research being done in by a medicine that will eventually help diabetics? guest: there is a lot of it. dr. insel will give you a better bet sample -- better example because jdrf is doing a lot of research on this. guest: imagine insolent in the body released on a -- insulin in the body released on glucose levels. that particular effort has been picked up by format, which illustrates that -- by pharma, which illustrates that we often work with biotechnology companies so that they can to get the full weight. -- take it the full weight. there are lots of advances on the device site. host: we are talking about bio medicine and a juvenile diabetes with dr. richard insel and scott whitaker. if you would like to get involved in the conversation, by all means, give us a call. my experience with the type 1 diabetes, we're talking about people -- by experience with type 1 diabetes, we are tal

it is that type of thing and that type of research being done. eventually, more research will be done to treat this dreadful disease. host: can you give an example of research being done in by a medicine that will eventually help diabetics? guest: there is a lot of it. dr. insel will give you a better bet sample -- better example because jdrf is doing a lot of research on this. guest: imagine insolent in the body released on a -- insulin in the body released on glucose levels. that particular effort has been picked up by format, which illustrates that -- by pharma, which illustrates that we often work with biotechnology companies so that they can to get the full weight. -- take it the full weight. there are lots of advances on the device site. host: we are talking about bio medicine and a juvenile diabetes with dr. richard insel and scott whitaker. if you would like to get involved in the conversation, by all means, give us a call. dixperienc fifth we're talkinabg about peoe who are our actually afflicted with diabetes. if you are a health cares,

those types of things. i realize those types of illustrations i were seeing were identical to the same types of interspecies monsters that we saw in the 17th century. when i started to write this book and wanted to ask three important questions. wanted to use the past test three important questions about where we are now. the first is, should society limit our science? the relationship between science and society is so precarious. the second question, if so, at what cost? i can't help but to think, were transfusions to have continued and would we have had transfusion much earlier, could we have determined blood type much earlier had the response to transfusion not stopped it in its tracks? because the experiment in the 1900's was simple, taking a little bit of blood from one colleague and a little from another. this blood a coagulated blood be? and then he ended up being able to do some graphs. he determines that the first initial blood types, it was not a hard experiment, and he did not the dots of tools.

it will be live music from all different types of genres and all different types of demographics, which for some people it is confusing because there is no set type of vibe at the sclub but i personally like it because it always stays different and interesting and that's part of the reason why i keep doing this. i can't help but bring this up. part of my security policy is going to include no high heels alive. [laughter] you have to be wearing flats. >> great. >> sorry. no disrespect. >> commissioner meko? commissioner meko: you have experience with other type 47 venn use? >> i do. i have a live music club in oakland and the hibiscus food program and live music program and the independent and the justice league never had food or don't have food. and so i don't have an abundance of experience but i definitely now have experience. >> what -- do you think about extra security needs for a venue that does direct a 121 crowd. have you taken that into account? >> when we have a show that will be promoted as an all-age show, we will have extra security. that is written into the contracts that i

and because of the genetic risk for type deacons type 1 dalia visas well characterized we can identify those at risk and follow this. this has allowed us to embark on bold, longer-term systematic studies to identify these environmental factors. this study has enrolled over 8600 newborns with high genetic risks for the disease, and we plan to follow them for 15 years. we will be collecting biological samples and information about their lives, identification comfortable, of an infectious agent that triggers this auto immunity could lead to a vaccine to protect against this disorder. .. is conducting trials of promising therapies in newly diagnosed patients. now, the third handoff continues along a spectrum of disease progression and this next age of disease research shown in green focus is on people with established type one diabetes. and a high priority for this stage is a development of new tools and technologies to help people improve their blood glucose control because they can reduce diabetes complications by up to 70%. this is certainly an artificial pancreas that automatically lin

. >> but for the blacks these type of instruments were not allowed to be played because they were too loud and for the church they will provoke movement that was not appropriate. >> (speaking spanish). >> they could also work as a form of communication with the drumming patterns. >> (speaking spanish). >> this was what was going on in africa. >> (speaking spanish). >> and from some of the sounds they used to play that we almost lost all of them we still have some that he remembers. >> (speaking spanish). >> for instance -- >> (speaking spanish). >> this means "attention be alert. something is going to happen". >> (speaking spanish). >> wake up. wake up. >> wake up, wake up. (speaking spanish). >> and this are some of the drumming patterns that have been rescued by the cultural association. >> (speaking spanish). >> the african and review itse s size. >> (speaking spanish). >> to the actual size that he has. >> (speaking spanish). >> the reason why this drum was reduced in its size it was the intention of hiding it from the dominant class so they will not be oppressed by playing it. >>

there is of course the legal question about which types of expenditures are opprobrious, which types -- are appropriate, which types of stores. i think one of the things that is worth pointing out -- of the last several years, we have gotten much more sophisticated as the city and in our planning about how we approach the interaction between our cash and spending. through the capital plan, we have started to really have a lot more nuanced discussion about the trade-offs and using cash expenditures. the biggest example, of course, is how we have funded streets over the past couple of years. i would probably not want to make the argument that a long- term financial strategy is to use general fund debt for streets. i think there are instances where it is a reasonable approach. in the capital plan, there is a greater need for the types of products eligible for debt, financing and the types of projects that are really cash on the types of expenditures like facilities maintenance. that need is great enough, that we would probably all like to be in a position with cash, but even our 10-year

there are types of unwise development. redevelopment statewide is in need of reform. san francisco is a model for redevelopment and it needs to stay intact. >> let's talk about the role of sports. are you happy with the plans for the america's cup? should the city spend money to keep the 49ers'? >> i am thrilled about the america's cup. it will not just be an economic boom that creates jobs and long- term economic development. it will help us shore up our aging and deterioration appears -- deteriorateing piers. it will help us clear of deferred maintenance. it will be a >>> promotion for the city. people will see the panoramic views of san francisco and want to come here. i would very much like to see forty-niners stay here. what that means, we will have to talk about it. i am not a big fan of massive public subsidies to sports teams. i think we should work hard to keep them here. >> we're almost out of time. are there any other issues or concerns we have not discussed? are there any other specific issues you plan to concentrate on throughout your turn? >> a couple th

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wild type males. males are larger than wild type males and they could have increased mating success because of that and they could have increased access because either the female prefers to mate with larger males or better by being larger they can drive away the smaller wild type competitors that are around and as a result of that combined. advantage with other males as well as the female preference we found at the transgenic males get more than seventy five percent of all the meetings so for example one thing we've also been assured is that the young don't survive as well and the mating advantage of the tragedy of males would drive that trans gene into the population more and more transgenic but the survivorship of the young is less and less through time. resulting in a smaller population size. quite likely the population could go extinct. genetic engineering to some extent is about a four hundred year old mistake it was a mistake that began with the cartesian revolution and this idea that life is a

different types of buildings are in the city. we have wood, unreinforced masonry, you have high rise and you have tilt ups. what's the safest construction type to be? four stories or less. wood? yeah, wood framed building. why is wood the safest building to be in, 4 stories or less? it flexes, yeah, it's flexible. what's the danger here? chimney, yeah, fireplace. be aware of the fact that just because it's a wood building and the event caused some sort of compromise of the structure of the building and the building is still standing doesn't necessarily mean there's not a danger there. so what could you as nert's do to make that situation better or at least keep it the same so no one else gets hurt? keep it off, yeah. keep people away. perfect. take out some of that yellow tape that you have, that yellow caution tape, and string it around around keep people back. in this particular case, what could you do to make that situation better? turn off the gas. where would you turn the gas off at? at the street, okay. that's a good place

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the job training and other types of programs that the mayor's office of economic and workforce of all men are working on are really important to ensure that unemployed people and potentially homeless people can be trained in the new green economy and green jobs. there is also a lot of other types of work force development being done, but i think it has to be targeted at some of the lowest income, highest vulnerability populations in our city, and that would help prevent homelessness from growing. but i hope that as we look at homeless policy, we take a man approached that does not blame homeless people for their own predicament but looks at how we can improve the economy, jobs, and educational opportunities for many people who are currently homeless. >> you started to touch on this a little bit as the city's housing needs. what do you think the board of supervisors should be doing to address some of those needs? supervisor mar: even as we will be holding a hearing on senior housing needs in a few weeks, we did a study with the budget analyst office that shows that there is a huge need

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it's a similar type of situation. we have a manual software to keep track of that information, but not to the extent that we like. again, we are fortunate because we see from years ago that we have a synergy with public works. a lot of the pavements are in such poor conditions, the surface is so rough that the markings would not adhere to them. so in some ways, we're tied in with t.p.w.'s work program. so we take advantage when they repave the streets and we go in and remark the markings on fresh, new pavement. and that's last anywhere from eight to 12 years, although we decided several years ago to ask that we turn over the striping every eight years. so on the average, we are doing that. of course it's not perfect because there's certain small areas that we might miss, but we rely on staff and also the public to give us input to fill in those little gaps. that would be the second area that we would tackle once we have the inventory system for the signs in place. we need some additional staffing to deal with the prev

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though the types of things that the federal government can do to support local level. occur due to look at it. of the san francisco going to participate in that. we in fair housing have put out new policies to protect 11 that are in public housing that may be subject to domestic violence. typically, if a crime goes on, in your unit, which is grounds for an election. if the crime happens to be domestic violence, it is blatantly unfair to pick that person or the whole family out because of the violence they were a victim of. that is potentially gender discrimination. some of the things that we are doing regarding lgbt families. traditionally, the mother has been -- the family has been mother, father, dodd, etc.. and our job to be reflective of what is going on america of 2011 is to be open to all families. we are setting up policies later this year that decision making on housing cannot be based upon sexual orientation. it can't be based on gender identity or marital status. ñ9q back and we can maybe shape regulation or law to be responsive to be reflective. >> what abou

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what it is required. >> it's a type 2 a 10 bc a size extinguisher that will fight the various types of fire. those are required in the common areas of the building. now, keep in mind that while they are required by the housing and fire code so you may see fire inspector asking for them and a housing inspector asking for them. in using them if a fire gets too big you want to call the fire department first they are there to fight small fires the size of a trash can. >> for 3 unit or more apartment buildings. in dwellings, having talked to the fire department they recommend you don't put it under the kitchen sink. you put it something where you can retreat from the fire, get the extinguisher out of the closet or hall way or some place away from the kitchen and fight the fire in the kitchen. you don't want it right where you expect the fire to be much here is a fire extinguisher it has a tag it's punched march 2006 serviced by international fire company in san francisco. that tag has to be updated annualy? >> another thing to note about fire extinguishers when you purchase them if you purc

. >> there are many types of slides. there is the bedrock slides which we are looking at in is a combination of a block slide and where the material is just out of balance and is falling off. rainfall pushes from the ground water and out of the cliff. as you can see, the slides artistic one of many types of landslides or slope failures. >> do we have all of these kind of failures in san francisco? >> unfortunately, we have them all. the rock from here is used from the sea wall. it came from this hill. it was a itgnoll that was present. because of this blasting that occurred, the rock is weak. while most of the time, there are times of heavy rain. sometimes, this has nothing to do with the rainfall. iraq is 50 to an old and then it just falls. in this particular area where we're standing, we have seen the wall at the base. >> the big steel beams with the fence. this is an effective way of preventing the rock that does fall from causing damage. that might protect the bottom of the hill but it doesn't do anything over the h