. >> could you be more specific about how uc nih fitting into the health-care debate? -- how you see nih fitting into the health-care debate? >> when you have a circumstance when there are more than one alternative, how do we know which one is the right one for that person? that takes research, carefully designed research, and we do not have enough of that. oftentimes, it is sort of a good guess. physicians and patients tried to muddle along. wouldn't it be great if we just knew the answer? >> you are getting $400 million from the recovery act. talk to me about how you structure competitive effectiveness impersonalize medicine where you can target cell populations and genes might be susceptible to particular diseases. how does comparative effectiveness not interfere with personalized medicine? >> something that there is a conflict between comparative effectiveness and person was medicine. you get the best of both. for someone who is already showing early signs of onset diabetes, there was a study done a few years ago by nih where diet and exercise is more effective tha