. >> this is a profound insight, which allows us to think that there may be a uniifying theme connecting these disorders, and perhaps allowing us to get a completely new therapeutic approach to this, that if we could solve any one of them in a fundamental way, we would revolutionize neurology. >> rose: episode eight of the charlie rose brain series two. the charlie rose brain series is about the most scientific journey of our time. understanding the brain. it's a series made possible by a wehave therapiesmons but they're symptomatic therapies, and that's what l-dopa is, as stanley made it so clear. the underlying disease process marches on. as eric said it marches by accumulating preons that spread to neighboring cells and more and more spread occurs and it's true of all these diseases we've talked about-- parkinson'sa disease, alzheimer's, chronic dramatic encephalopathy talzheimer's, als, motor neuron disease, and huntington's disease. so we've got to get at these proteins that are turning into preons and stop them. i've marked three possible intervention points. so one is that we decr