. >> rose: jay bilas, walter isaacson, charles duhigg when we continue. captioning sponsored by rose communications from our studios in new york city, this is charlie rose. >> rose: the n.c.a.a. basketball tournament is in full swing. a field of 68 teams is down to the sweet 16. the games will be played tomorrow and friday in arenas across the country. all four of the top seeds remain in contention. they are kentucky, north carolina, syracuse, and michigan state. kentucky has dominated all year, the wildcats look to avenge an early season loss to indiana on friday night in atlanta. north carolina enters week two with a big concern at point guard. its top play maker kendall marshall broke his wrist in the second round last weekend. his status is uncertain. joining me from charlotte, jay bilas, he is a college basketball analyst for espn and a world-class attorney. i am pleased to have him back on this program for march madness. welcome. >> thank you, charlie. great to be with you, as always. >> rose: what do you think of the tournament so far as predicted

we will be led into lunch by author and policy thought leader walter isaacson talking about leadership and drawing on the recent biography of steve jobs. then at lunch weve of hosting senator john kerry will who will be sharing his perspective on congress. he'll be super keen to answer your questions. we should take advantage of the opportunity to one of the department's biggest advocates to ask him his guidance. this is afternoon we've arranged a very useful series of seminar styl sessions as well as other information on discreet areas ofeie with a town hall session here with the secretary as well as with the washington-based leaders here to be able to be answer any questions and actually have a flee-flowing discussion. then i just want to take a quick moment to flag during the break there is a number of department who have set up different points of contact where they can answer questions about programming and offer other information that you all might find useful out in the field. if you could take a moment to go through there, that would be useful to you. before we get started, i w

billionaire genius which business week has compared both to and leonard caper and trashy analog to walter isaacson's biography of steve jobs. king larry begins on may 21st, 1995, which if you were in the state was heavily from the adjacent and murder trial. but with a beautiful sunday morning hand a small plane who took off from the airport with two important people on board. one was the speaker of the house of the commonwealth of the northern mariana islands and the other was mary home better known as dhl. .. >> so a number of his friends had declined to make the trip with him that morning, and no one was terribly shocked that this plane had also gone down. however, it was a real shock that larry hillblom was suddenly gone. he'd arrived there 15 years before, and he'd become a larger-than-life character in the mariana islands. he bought the bank, he bought the airline, he bought the television and radio stations, he built dozens of businesses including the pawnshop and had been a bartender, so he was very well known. and there was a sort of myth those that was just incompatible with him being dead.

jobs was trying to survive to see his son at his high school graduation to his was a quote to walter isaacson. i think the biggest innovation of the 21st century will be the intersection of biology and technology. that's what we are talking about tonight. so now let's talk more about the real biology, not just ideology of all these different metrics. let's talk about sequencing. that's still digital. for characters. but all of us basically, each of us i should say are just billions of zero ones actg, from a medical standpoint. yes, we have a soul and personality, and we're human and all that stuff but from a medical personality you only need six characters. the way we sequenced people in the past was using these next-generation devices that cost seven, $800,000, next-generation of sequencing the not only would incredibly expensive but we had to buy these proprietary agents and these were formidable. we are in this era. this year in january we thought this is really big. life technologies announced this, not yet feasible will be later this year can sequence a whole human genome 40 times, seque

community of conscience and the leadership of the museum for organizing this evening and on behalf of walter isaacson and the aspen institute how glad we're partnering on this important event but partnering on this particular subject comes to us naturally. i'm proud to say harold coe was a regular moderator at the seminar for judges run for many years at aspen's white river facility by our merida director with professor lewis hankin of columbus law school two key developers and components of the modern field of human rights and humanitarian law. some of the justice and society programs' recent efforts are focused of development of the rule of law around the world including in the arabian gulf and the spring countries and i want to observe that it is through the rule of law, through vigorous legal and judicial institutions that we are able to prevent the perpetration of the most grievous offenses by the unbrideled against discrete and insular minorities. tonight we'll hear of the courts and more recently the international criminal tribunal for the former yugoslavia and the international tribunal for r

a famous book written by walter isaacson writ steve jobs recently and here is quote from the book theking. we told the publishers we go the agency model. where we set the price, you set the price, publishers and we apple, get our 30%. the customers pay a lot more. that's what you want anyway, we're left, jenna, paying more for the books than we ordinarily wouldn't have. we don't know the other side the publishers and others refused to comment. jenna: i know you're a big apple guy. you have a iphone and ipad, all that sort of stuff. >> yes. jenna: i have a kindle though. what about amazon, barnes & nobles? there are a lot of different devices in ebooks. are they involved at all in? >> no but they kind of started this when you think about it. amazon, which is interesting the agency model dell previously the wholesale model the it was sold half price. $24 book sold for 12 bucks. amazon comes in with the kindle we'll give you to you for 9.99. publishing companies hated that. maybe that is why they were quick to make a deal with steve jobs. the publishing companies didn't basically want to

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we will go to lunch with walter isaacson, who will talk about leadership and drawing on the recent biography "steve jobs." at that lunch, we have the honor of hosting senator john kerry, who will be the keynote, sharing his perspective on congress. i know he will be super keen to answer your questions. we should take advantage to that opportunity, having one of the department's biggest champions here. this afternoon, we have arranged what i hope you will find to be a very useful series of seminars-style break out sessions, as well as other information on discrete areas of foreign policy. we will close to the tunnel session here with the secretary, as well as with the washington leaders here. i want to take a quick moment to flag that during the break, there actually is in the exhibition hall a number of departments who have set of different points of contact where they can actually answer questions about programming and offer other information that you might find useful in the field. if you could take a moment to go through there, i think that would be useful to you. before we get started, w