warburg bank. and trento is a product of these other warburg senate the time it was unusual for somebody of jewish descent to rise to a high academic position and his father really rises all of the way to the top of the civics world and otto warburg present the sum of the greatest scientists in history. a regular einstein it was very close to camille warburg and fisher and was great chemistry to so many of these world-famous personalities and someone, they had already one the nobel prizes enterprises added otto warburg pretends to be a world changing scientist in his life. he grows up with it. his natural surroundings and what he feels is expected of him. and the question in his mind is really not busy going to make world changes discoveries but in what field it's going to be. many does feel a certain competitiveness with his father. i think he was out to him. but that's not easy to date, and einstein loved his father. any help show this some of einstein's theories were correct. he provided experim

all of those things from warburg and then it got lost and then now, why now? >> sure the story really picks up again and warburg gets lost in in the late 1990s these molecular biologist that are focused on cancer in the modern sense of looking at mutated genes and how these signals go out from one protein to the next which causes the cell to replicate in the fundamental to cancer which is replication into their creating genetic pathways and they lead them back and they seem to be causingan metabolic enzymes to change interrupt the activity and it seems like one of these old world enzymes itec seems peculiar to them because they literally called them housekeeping enzymes, sure they don't need the energy but that's afterthought the energy comes in when they need it the cancer networkthn seems to be bringing them back to these fundamental model bought a and dimes and a few scientists rather than ignoring this and thinking this is irrelevant, strange they got to curious, why is metabolism being connected to all of this and they start to look for the connection of

warburg bank. otto warburg and his father are cousins of these other warbirds and at the time it was unusual for summit of jewish descent to rise to high academic position. his father really rises with all the way to the top of the physics world and auto grows up in this house that is full of the world's greatest physicist come some of the great scientist in history, max, einstein very close, neil fisher, the great chemist. many of these world-famous personalities to go on at the happen to winin nobel prizes and otto warburg and tends to be a world changing scientist just like the people he grows up with, his natural surroundings, when what he feels is expected of him. the question in his mind is really not easy going to make a world changing discovery, but in what field b it is going to be. and he does feel a sense of competitiveness with his father and wants to out to him which is not easy to do. his father, einstein loved his father and he helped actually show some of einstein series were correc

could that be driving, you know, what they call the warburg effect or the warburg metabolism. sure enough, there is a remarkable body of evidence which suggests that insulin is playing a huge role in human cancers. insulin is a growth factor. it is a growth hormone that, you know, tells cells to eat and to divide and grow, and they have known really since -- for decades that people with elevated insulin have higher levels of cancer, so this has been known for a long time. it also only sort of became clear in the 90s, and a number of fascinating discoveries were made. one, first of all, it became increasingly clear that insulin drives obesity and obesity is linked to cancer, but insulin also activates all these signalling networks that i talked about before that are changing the way a cell eats. scientists use the word downstream. they are downstream of insulin. insulin activates them in the same way that a mutation would. it sort of causes them to rev up and keep going and keep taking up nutrients. now, insulin is a natural hormone. we all need it. but, you know, when you have

there focused on otto warburg and cancer science. any explain it in this book. it is truly bizarre.yes, i thought so too great was absolutely fascinating. almost hard to put somewhere in your head up in any way that is what happened. and now, let's continue on. might be getting my timelines well, he left the lab and he moved the u.s. for a while and drove this foresight is absolutely crazy was a very kind soul that was just didn't know when that happened and why and then what happened after. >> after this event i told you he makes it to the end of the war not only if he survived in 1942 bombs started to fall sorry, 1943 started to fall and he is essentially moved to a new institute which is sort of a refurbished mansion on a favorite stateus in the german countryside and this is at a time by the late 40s when nobody's allowed to use gasoline or building materials to build a new institute. he gets in trouble again and is almost arrested again but in the end, he survives and has an extraordinary treatment, so the soviets come to power and take over the other part and sort of caught in