that both, both in terms of the biomedical developments, wissink but also some of the changes in terms of the key to delivery systems are really important. the things we're emphasizing today really is also about the need to deal with some of the policies and restrictions that make it light that make it extremely difficult for people to accept a services. whether it's discriminatory policies towards sex workers. whether it's men who have sex with men, or people who use drugs, and indeed, adolescent girls and young women, we have 5 and a half 1000 new infections amongst young women in east and southern africa each week. i'm. this has to be addressed fundamentally, good developments, but we are very, very concerned outside of the cup at 19, a pandemic that we are off target needs to be addressed. and let me ask you this. we are potentially just a week away from 1000 vaccine. yet there's still no assigned maxine for hiv aids. why is that? so there are, there are ongoing trials and it's an exciting if we can investment and research into this and i think i think what has been achieved. think