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revealing the stunning scale of the disaster in the city, a popular cruise line stop. the massive landslide crushing homes, sweeping over roads. at least one killed when a vehicle was swallowed up. mandatory evacuations as the community braces for more rain and another potential landslide. also tonight the late august scorcher. dangerous heat threatening to break records. more than 50 million on alert in the midwest. the duel over the debate. the new request by the harris team over muting the microphones that has donald trump threatening to skip out. this just in. special counsel jack smith trying to reopen the trump classified documents case after the judge tossed it out. the appeal just filed. in the northeast the urgent warning about mosquito-borne diseases. officials ordering entire communities to be sprayed. some towns issuing curfews. what you need to know. cheaper copycat versions of popular weight loss drugs like wegovy.

why some medical professionals are now turning to them. walmart recalling apple juice sold in 25 states. the potential danger. and the thrilling extra-inning victory. meet the little leaguer who made the big bunt to win the world series and the emotional show of sportsmanship. >> announcer: this is nbc "nightly news" with lester holt. and good evening. i'm tom llamas, in for lester. tonight we start with a state of emergency in alaska and a community on edge after a landslide struck in the popular tourist destination of ketchikan. from above you can see the giant swath of forest gone. all that's left is that muddy streak. and below, parts of the town buried. creeks turned into raging brown rapids with whitecaps. ketchikan is a popular tourist area, drawing more than a million visitors a year, especially by cruiseships.

but passengers were told to stay away from the area today, with the slide zone still unstable. and now the mayor there telling us tonight his fear, that a quarter of his town is at risk for yet another landslide. morgan chesky reports tonight. >> reporter: tonight, frightening new glimpses of an alaskan town partially buried after a hillside collapsed. the devastating landslide crushing entire homes. >> we were just at that house for a garage sale last weekend. this is terrible. >> reporter: sunday's tragedy unleashing a deadly wave of snapped trees, toppled power poles, pushing a mountain of debris into a hillside neighborhood. the slide sideswiping the town of ketchikan, a seaside destination on alaska's famed inside passage and a frequent stop for cruise lines. officials confirming one person was killed while driving when the slide swallowed their vehicle. >> i was stunned because in my 65 years here i've never seen anything of that scale.

>> reporter: mayor dave kiffer calls the loss of life heartbreaking but stresses the current damage zone could spread even further. >> there's about a quarter of the town currently at risk for yet another slide. >> yes. >> how frightening is that? >> it's very frightening. to be honest, i don't think any people in think any people in ketchikan walk about their daily lives thinking that mountain's going to come down. and now we have to. >> reporter: as for any cause, officials say the landslide struck following an unusually dry august. >> look at that. >> reporter: when a weekend storm left conditions soaked. >> it's definitely heartbreaking to see. it affects your mind tremendously. it's traumatizing for sure. >> reporter: leah canfield one of several whose homes were damaged. all too aware this may not be over. >> and morgan, as you know, that's the big concern tonight. what is the potential for another landslide? >> reporter: yeah, tom, the potential for a secondary landslide is very real. with that prime area of concern south of the original slide site. and that is why tonight evacuation orders remain in place

for multiple neighborhoods in ketchikan. tom? >> all right. morgan chesky starting us off tonight. morgan, thank you. and beyond alaska tens of millions of americans face weather threats. scorching heat and severe storms in the plains and the midwest. dylan dreyer's here tonight for us. and dylan, this is especially hard on places like chicago where school's just started. >> school's started and perhaps ac's not pumping and when you're looking at heat indices up to 115 degrees it is certainly dangerous outside. we do have our heat advisories and heat warnings in effect. we are looking for high temperatures tomorrow to get up once again close to 100 degrees. st. louis should hit 100. the heat index will be 108 degrees. then on wednesday we're going to see more of that heat. now starting to trickle farther to the east. baltimore up to 98 feeling like 105. with the heat does come some storms too. and we have two areas with thunderstorm watch right now. some severe thunderstorm warnings too. large hail, damaging winds, and isolated tornadoes are possible.

tomorrow that threat moves over into the great lakes region where we could see hail and wind as the biggest threats and then eventually it reaches the mid-atlantic by wednesday, tom. >> all right, dylan, we thank you for that. and this is developing tonight. special counsel jack smith asking an appeals court to reinstate the classified documents case against former president trump after federal judge aileen cannon threw it out. ken dilanian is following this for us. and ken, it seems jack smith is really going after that judge's decision. >> reporter: that's right, tom. jack smith is arguing that judge aileen cannon fundamentally misunderstood the law when she ruled that his appointment was unconstitutional. more than a year after mr. trump was accused of unlawfully taking classified documents to mar-a-lago including storing them in a bathroom cannon tossed the case last month, ruling that no law supported the hiring of a special counsel without senate confirmation. the doj is now asking an appeals court to reverse that, calling cannon's reasoning nonsensical. but november's election will come long before this appeal is resolved, and if mr. trump wins he can orders his doj to drop all criminal charges against him.

tom? >> all right, ken, we thank you for that. also tonight the new showdown over the upcoming presidential debate. former president trump raising doubts if he'll attend, and the harris campaign demanding a new change to the rule about muting microphones. here's garrett haake. >> reporter: tonight the trump and harris campaigns dueling over next month's critical presidential debate. this morning trump casting doubt about attending. and now a new wrinkle. >> the deal was we keep the same rules. now all of a sudden they want to make a change in the rules because she can't answer questions. >> reporter: in the last face-off at the biden campaign's request candidates' microphones were muted while the other candidate was speaking to prevent interruptions. but now the harris campaign is asking for the mics to be left on at all times. trump's campaign objecting. but the candidate seeming to acquiesce today while taunting the vice president. >> doesn't matter to me. i'd rather have it probably on. the truth is they're trying to get out of it because she doesn't want to debate. she's not a good

debater. she's not a smart person. >> reporter: vice president harris has been off the trail since her acceptance speech last thursday. sources tell nbc news she held at least one mock debate. >> we've got 75 days to go. so maybe for better and for worse that's the way i am, like that was good and now we've got to move on. >> reporter: all of it as former president trump was in battleground michigan looking to step on any harris post-convention bounce. campaign sources tell nbc news he's planning more aggressive fall travel. and while polls show voters give harris the advantage on health care and abortion rights, trump aiming to hammer harris on two issues where they show she's vulnerable, the economy and the border. >> under kamala harris american veterans are treated worse by far than illegal aliens. illegal aliens. you ever see them? they stay at hotels. we have veterans sleeping on the streets. >> reporter: speaking to a national guard conference trump slamming the vice president over the chaotic withdrawal from afghanistan, where 13 u.s. service members were killed three years ago.

today trump laying a wreath at arlington. >> the humiliation in afghanistan set off the collapse of american credibility and respect all around the world. >> reporter: harris today writing of the fallen, "my prayers are with their families and loved ones. my heart breaks for their pain and their loss." >> garrett joins us now live. garrett, let's go back to the debate for a moment. the harris campaign is now responding to trump? >> reporter: that's right, tom. a harris campaign aide says the former president should honor his commitment and after trump earlier suggested he's fine without those muted mics the harris campaign insists everything's now set. but tonight trump still says he's still thinking about whether to do the debate. tom? >> all right. garrett haake with some new reporting from the campaign trail. garrett, thank you. we want to head overseas now. new developments in that superyacht that sank in violent weather off sicily, killing seven people. the captain is being investigated for possible manslaughter and causing a shipwreck. that according to a lawyer for the captain, who's being questioned by sicilian prosecutors. he is one of 15 survivors and so far has not been charged.

russia today launched what's being described as its biggest attack on ukraine in weeks. firing more than 100 missiles and launching just as many drones all over ukraine. at least four people are reported killed. erin mclaughlin is there for us tonight. >> reporter: in kyiv a russian missile strikes near a critical dam, stunning ukrainian soldiers. part of russia's latest attempt, the ukrainian president says, to terrify. russia launched more than 120 missiles and 100 drones, he says, killing at least four and damaging civilian infrastructure, triggering rolling blackouts in the capital and sparking international condemnation. >> we condemn in the strongest possible terms russia's continued war against ukraine and its efforts to plunge the ukrainian people into darkness. >> reporter: the attack days after ukraine marked its independence with a somber ceremony in the capital. this morning our team woke to the sound of explosions and took

shelter, as did millions of other ukrainians. metro stations once again doubled as safe havens. yet within hours life returned to normal as the fighting rages on and ukrainian commanders braced for a long war. >> we fight for our freedom. >> reporter: two years ago we met colonel igor obolenski shortly after his men pushed the russians out of the area around kharkiv. since then he fought in the battle for bakhmut, one of the bloodiest of the war. >> the last time we met you told me something that stuck with me, that you were fighting for your little boy. >> yeah. >> so that he didn't have to. >> yeah. >> when your son becomes a man, do you think this war will still be going? >> maybe, yeah. but it's not very effective not very active phase but yeah, it will be. >> reporter: today ukrainians say of the 127 russian missiles

fired at ukraine today they shot down 102 and there are reports the drones were made in iran. tom? >> erin mclaughlin for us. erin, we thank you. in 60 seconds it's one of the most talked about festivals on the planet. tonight the tragic start to the burning man. what went wrong? and new concerns about potentially deadly viruses being spread by mosquitos. why some towns are warning people to stay inside. right after this. i was stuck. unresolved depression symptoms were in my way. i needed more from my antidepressant. vraylar helped give it a lift. adding vraylar to an antidepressant is clinically proven to help relieve overall depression symptoms better than an antidepressant alone. and in vraylar clinical studies, most saw no substantial impact on weight. elderly dementia patients have increased risk of death or stroke. report unusual changes in behavior or suicidal thoughts. antidepressants can increase these in children and young adults. report fever, stiff muscles, or confusion, as these may be life-threatening, or uncontrolled muscle movements, which may be permanent. high blood sugar, which can lead to coma or death, weight gain, and high cholesterol may occur.

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michelle bratti says it's rare but dangerous. >> it is very serious. even those that survive, neurological disorders and many health complications can happen from triple e. >> reporter: and so far one reported case in a person. an 80-year-old man was diagnosed with the first human case of triple e in massachusetts since 2020. cases also popping up in vermont and new jersey. >> symptoms range anywhere from nausea, very much like flu-like symptoms, but it could be nausea, dizziness, headaches. >> reporter: the new concern over viruses spread by mosquitos comes as the west nile virus hits 31 states nationwide. one of those cases, infectious disease expert dr. anthony fauci, recently hospitalized with the virus, now recovering at home. experts say simple precautions include wearing long pants and long sleeves, using mosquito repellant and removing any containers with standing water.

back in plymouth, officials worried after a horse testing positive. parks closed to all outdoor activities from dusk until dawn, when mosquitos are most active. authorities say if you are bitten by a mosquito and flu-like symptoms occur within two to ten days you should check in with your doctor. tom? >> rehema ellis with some important tips tonight. rehema, thank you. also, this year's burning man festival off to a tragic start. authorities say a 39-year-old woman is dead after being found unresponsive on the first day of the annual event in nevada's black rock desert. the cause of her death is still under investigation. okay. we're going to take a quick break. and right up next, pricey and hard to find. those popular weight loss drugs have some now turning to copycat versions. inside the debate over the pharmacies that make them. stay with us. whistleblower. [ distorted ] i just think everyone should know there's an insurance company out there exposing other companies' rates so you can compare them and save. hmm. sounds like trouble. it's great, actually! it's called autoquote explorer from progressive. here, look!

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the insiders won't change a system built for their benefit. i'm daniel lurie and san francisco needs a mayor unafraid to take on the status quo, bring accountability, and stop the excuses. welcome back. we have a consumer alert for you. walmart recalling nearly 10,000 cases of its great value brand apple juice. you see it right here. due to elevated levels of arsenic. the recall affects products sold in 25 states. walmart says it has removed the juice from its stores and is investigating. also tonight, one american is dead and another was injured when an ice cave popular with tourists suddenly collapsed in iceland on sunday. authorities have not publicly named the man who was killed. police say the woman who was hurt suffered non-life-threatening injuries. also tonight the super popular weight loss drugs like wegovy, they've been proven to be extremely effective, but for

many the price puts them out of reach. now some are turning to cheaper, copycat versions. but are they safe? stephanie gosk reports. >> reporter: in this office park on long island pharmacists are producing one of the hottest commodities on earth. not popular weight loss drugs wegovy or zepbound but medications they say are in fda terms essentially a copy. >> what does essential copy mean? >> the formulation actually comes from the manufacturer. it's in the package insert. >> it's a recipe. >> it's a recipe. >> reporter: that recipe mixed at hundreds of compounding pharmacies like this one nationwide, using ingredients purchased from fda-registered manufacturers. >> and this is semaglutide powder? >> semaglutide powder. that's exactly what it looks like. >> how are you allowed to do that if there is a patent on these drugs? >> the fda allows for this. if the patient needs medication and it's on shortage the only way they'll be able to get it is to come to a compounding pharmacy and let the pharmacy make it for them. >> reporter: it's a little-understood part

of the multibillion-dollar weight loss drug industry. federal law allows state-licensed compounding pharmacies to dispense drugs that are essentially a copy of fda-approved medications. only to patients with a prescription and only for medications in shortage, which includes wegovy and zepbound. compounding pharmacies often sell them at a steep discount. usually $100 to $400 per month, compared to roughly $1,000 for the name brands without insurance. elizabeth kenley needed to lose 50 pounds for a double knee replacement. she struggled to find the brand name drugs in stock and at a price she could afford. >> how are you doing? >> reporter: so her primary care provider suggested a compounded version. >> did you have some questions? >> i had a lot of questions. i was a little nervous. but i did talk to my doctor about it a lot. and then i went and talked to the compounding pharmacy. >> reporter: and it's working. she's lost about 25 pounds. >> i've had just mild,

mild side effects. >> reporter: primary care provider leanne owens, once a skeptic herself, says she and many of her duke health colleagues have come around. but only in certain cases. >> the thing that makes me most nervous is using unregulated compounding pharmacies that are selling the medication direct to patients without a prescription. >> you worry about patients who might be buying these medications online or something. >> correct. but using a trusted provider who's using a licensed compounding pharmacy is safe. >> reporter: drugmakers novo nordisk and eli lilly strongly oppose the practice. in statements to nbc news they stressed that compounded drugs lacked the same regulatory oversight as fda-approved medicines and can pose significant safety and effectiveness risks to patients. for patients like kenley there's another risk. >> it could be taken away tomorrow if there's no longer a

shortage. then we wouldn't be able to access this medication through the compounding pharmacy. which is scary. >> because there's no other option. >> there are no other options. and this option clearly works for people. it's life-changing. >> stephanie joins us now in studio. so stephanie, let's pick up right there. these compound pharmacies can make these drugs as long as they're on the shortage list. do we know how long there's going to be that list? >> that's the thing, tom. we do not. and when they come off the list the compounding pharmacies have to stop making them, which means patients who are relying on these versions of the drugs could be cut off. >> all right. stephanie gosk for us. stephanie, we thank you for that. up next the good news tonight about the little hit that scored big and won this florida team a world championship. (vo) you might be used to living with your albuterol asthma rescue inhaler, but it's a bit of a dinosaur, because it only treats your symptoms, not inflammation. treating both symptoms and inflammation with rescue is supported by asthma experts.

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finally, there's good news tonight about the newest little league world series champions and the young hero who proved that winning isn't always about swinging for the fences. bottom of the eighth. extra innings in little league play. man on second. hunter alexander at the plate for lake mary, hoping to just advance the runner against chinese taipei when this happened. >> he gets it down. oh, it's -- >> reporter: what a bunt. chinese taipei's cie we zuh along with his first baseman both going for the ball, leaving the bag wide open.

>> lake mary's going to win the little league world series championship! >> once you made contact and the ball started to roll tell me everything you were thinking. >> was thinking just stay fair, stay fair. and i look up and nobody's at first. and that was just great. >> and when he -- did you see him throw the ball into right field? >> yeah. i mean, right after i looked up and i see that ball flying by me i'm like let's go. and we won it. >> reporter: teammate nathan norton was the player who scored. the day before he had to sit out because of a 102 fever. but on sunday when chinese taipei committed that error at first norton ran as fast as he could, rounding third, stepping on home plate for the victory. >> it feels pretty great. i mean, we won the little league world series and i got the walk-off. >> reporter: the walk-off bunt a thrilling end for lake mary but devastating for chinese taipei. leading nearly the entire game, to go down with that wild play at the end. >> and all the florida kids are gathered and holding and hugging and consoling the kids from taiwan. >> reporter: for lake

mary celebrations on the field, outside the stadium and all the way back in central florida. >> got like 100 texts right after the game from my friends telling me great bunt, good game, congratulations. >> what do you think you learned from that game? >> keep fighting. i mean, we stayed alive. we kept it going. and we never quit. >> reporter: a victory not only for these little leaguers but for the state. the first title for florida after nine tries. all because of that bunt heard around the world. >> and a big congrats to both teams. especially lake mary, that showed so much heart. that's "nightly news" for this friday. we thank you for watching. i'm tom llamas in new york. for all of us here at nbc news, have a good night.

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