"come on man, i know cleveland-- lebron james!" >> woodruff: and a conversation with scientist francis collins about cracking the human genetic code 10 years later. >> it is just the foundation of everything with do and we have that information now. so for a scientist, this is incredibly empowering. >> brown: that's all ahead on tonight's "newshour." major funding for the pbs newshour has been provided by: >> this is the engine that connects abundant grain from the american heartland to haran's best selling whole wheat, while keeping 60 billion pounds of carbon out of the atmosphere every year. bnsf, the engine that connects us. >> and by the bill and melinda gates foundation. dedicated to the idea that all people deserve the chance to live a healthy productive life. and with the ongoing support of these institutions and foundations. and... this program was made possible by the corporation for public broadcasting. and by contributions to your pbs station from viewers like you. thank you. >> woodruff: reaction rolled in today after

you and lebron james didn't put on matching dresses? there's nothing i won't do is the point. >> larry: i get that. how long is this reality show going to go on? >> until the day i die. until oprah kills me. which i think we know is imminent. i think we know that's -- >> larry: why does she hate you? >> you know why? because i see through her. because i get her. i've lifted the mask off. and i see what's inside. do you know what's inside? >> larry: what do you see? >> i think stedman is missing. i think stedman is missing. have you ever seen stedman? >> larry: yes, he's been on this show. >> was he a hollow gram or a person? >> larry: a person, i think. >> are you sure? >> larry: i can't swear. >> exactly. >> larry: i got it. >> i also believe ryan seacrest is out to get me. >> larry: why do you think so? >> because she makes fun of me sometimes. >> larry: did you say her? >> yes. i'm starting right out the gate. >> larry: you recently did an emmy round table of reality stars for the hollywood reporter. you said you think your show edit

you and lebron james didn't put on matching dresses. >> larry: okay. >> there is nothing i won't do is the point. >> larry: i get that. how long is this reality show going to go on? is it reality forever? >> until the day i die. until oprah kills me which i think i know is eminent. >> larry: why does she late you? >> you know why? because i see through her. i get her. i've lifted the mask off, and i see what is inside. you know what is inside. >> larry: what do you see? >> first of all, i think stedman is missing. i think stedman is missing. >> larry: there is no stedman. >> have you ever seen stedman? >> larry: yes, he has been on the show, sitting that seat. >> was he a person or a hologram? >> larry: i can't swear. >> exactly. >> larry: okay, i got it. >> i also believe that ryan seacrest is out to get me. >> larry: why is he mad at you? >> because i make fun of her sometimes. >> larry: who did you say? her? >> yes. >> larry: you're funny. >> i'm starting right out the gate, lar. >> larry: you recently did an emmy roundtable of reality stars for the hollywood reporter. you said you

and lebron james friday night. we're very diversified. we have a question for you, gaga.. is it true michael jackson wanted to perform with you on his "this is it" comeback tour? >> you know, it's always very difficult, because i don't necessarily like to talk about those very personal things that happened. i guess i can speak about it now. i was actually asked to open for michael on his tour. and we were going to open for him at the o2, and we were working on making it happen. >> larry: wow. >> and i suppose i believe there was some talk about lots of the openers doing duets with michael on stage. but michael's death was devastating for me regardless of whether or not i was supposed to go on tour with him. he's such an inspiration and remarkable human being. i guess i suppose, larry, some of my fascination with death and the demise of the celebrity goes along with me watching these hugely iconic and amazing people that i have heralded and admired my whole life become destroyed. whether self-destroyed or destroyed by the media. >> larry: how did you come up the -- with th

we had lady gaga, we had bill gates, we had president obama, and lebron james. and i'm flying home from that week and i'm thinking to myself, i have a done 50,000 interviews. i'm never nah top this i want to go on, i want new horizons, i want to try other things. i would like to stay in some way with cnn this whole thing was put together in four or five days and i'm here, ready to carry on. i will be on tomorrow night and -- >> i did hear people say well, larry didn't really understand lady gaga who understands lady gaga? please. >> larry: i liked her. >> i was think hog else gets lady gaga to come on their show? i never saw lady gaga anywhere else. talk. >> larry: we got you a lot. >> i saw her wearing an aquarium on her head i never saw her actually speak to another human being. i have no idea what she was like before she talked to you. >> larry: this is a mixed emotion. a staff, i want to see them all, but more time with the wife, more time with the kids, more time to spend and more time to do other things. in other words, i can do things now that i wasn't ab

the thing lebron james, how many seasons would have to play to get $1 trillion? 25,000 seasons at $40 million would be $1 trillion. one reason people are not as angry as they are is the numbers are so huge. a saying in washington to $1 trillion is the new billion. what we started talking on the show about the budget 10 years ago, we were talking about billions. now talking about trillions. the other day i saw this wonderful bumper sticker and said, thank god obama does not know what comes after a trillion. these politicians are spending money like it is monopoly money. host: what about -- is there room in your view for defense cuts? guest: there is. no question. if i were president obama's economic czar, the first thing i would do is exactly the opposite of what paul krugman recommends. i would call for a 15% across- the-board reduction in spending -- every government agency. then i would freeze the spending at current levels until the revenues catch up. we've got to balance our budget but we have to balance it by growing the economy and reducing government spend