we'll be looking at preexposure proflax sis and the impact of treatment or both incidence and death rates. i think there are very exciting possibilities. we know that treatment works as prevention between one individual and another. we're going to focus now on treatment as prevention on a population basis and document the impact of that. and optimize it so that we can do it as effectively as possible. we're also looking at the impact of pepfar and hiv programs on systems. not only has pepfar achieved its targets, not only has it done that with steadily declining costs, but it's done that at the same time we've been able to strengthen systems. health care systems, public health systems, delivery systems, community efforts to improve health. and that's something to be celebrated an built on moving forward. combination prevention is something that would have been virtually unimaginable ten years ago. no one entity can do this alone. but i think working together, we can achieve a society in which infant infections are rare. progression from hiv to aids is rare. hiv treatment is effective and