dr. inglesby. the short-term benefit of research, we wouldn't do a lot of research at the nih, because you very often have a situation where it is incremental and you build up into something that really becomes important. so although i understand the point is being made, if you look at what immediate benefit of those mutations are going to have right now, sure, you can say that there isn't a lot of surveillance capabilities, or high sequencing, et cetera. but the incremental accumulation of knowledge is one of the fundamental principles that the nah -- the nih research is built upon. i think is a bit of a disagree on the. i don't think you need to have an absolute media benefit to research not to be ultimately important to do and to publish. >> do you want to respond? >> yes. actually i complete agree with wages since i don't think we disagree on the. i agree that fundamental research and understand biological risk is both critical and is a part of the, critical part of the science mission. this is