it's really more a very few animal studies, and in the case of sacrin, there was an animal study thathowed they caused bladder cancer in rats. it wasn't even a mechanism that was even possible in humans. we don't have convincing research. this is more hype. really a little bit blown and more hype and a little bit blown out of proportion. >> does fake sugar make a person crave more food and more calories? i remember a few stois a few years back, people who drink diet soda weigh more than people who don't. is there a craving component? >> yeah. that's great question. it's really interesting because a lot of studies show that diet soda is linked to being overweight. we know that some of these artificial sweeteners do cause a lease of insulin and drop your blood sugar and make you crave more and they cause the same addiction like pathways in the brain. we don't know the answer at this point. >> that's good advice. we'll have you back soon. thank you. >> good to see you. >> i'm going to introduce you to this transplant surgeon who became a better doctor after needing a transplant himself.