novartis is a swiss-based company. we are leaders in eye care, leaders in pharmaceuticals and leaders in generics with our sandos division. and right now you heard this morning we're really in a moment of innovation that is really helping people live longer, healthier lives. last year, as you heard from doug this morning, 50 new medicines were approved last year by the fda which is the most and the highest in about 20 years. and so as we look at that, it reminds me we probably, some of us, have seen this actually take place, the change in our own families. when my mother was 49 years old to, she was diagnosed with breast cancer, and in those days it was the chemotherapies that we know about today and their toxicities. and unfortunately, she passed away the same year the inhibitors were approved. and had she had access to that innovation, my sisters and i would have got another 18 months to five years with her to create more special moments together that we missed. fast forward, when my sister turned the same age, 49, s