it was for sean parker. and i thought, the one thing that jonathan doesn't have access to that i have to have is he has to have a little venality. and you can't fake it. he has -- there was a little bit of the oily salesman, just a tiny bit. >> charlie: in sean parker. >> not offense to scene -- sean parker because i've not met him but i needed to know he would make 10%. i say this often but i think part of what makes a great performance is, at some level, you shoot a 14-hour day and six days a week, at some point people are going to be exhausted. there has to be an inherent thing in the actor you can't beat out of them with a tire iron. that you know is always going to be -- it's always underneath that surface. curiosity, decency. and with holden, i think people mistakenly think of it as earnestness but it's a hunger to be better. it's a hunger to understand. >> charlie: we are living in the midst of a podcast boom with the rise of mobile more people are consumining content in transit than ever before. podc

. >>> peter thiel and sean parker are financing a secretive cancer fighting startup a source tells cnbc the company called 3t bio sciences raised more than $12 million in a massive seed round the firm is looking at ways to use the body's own immune system to fight off company we don't know much about the company but it is being run by a group of academics from stanford. >>> google announcing a bunch of new products the company doubling down to its commitment to the hardware business as it competes with devices from amazon and apple. some of the devices were the google home mini and max a high-end pixel book laptop that runs the chrome operating software, two new phones the pixel 2 at at $600, and the pixel 2 xl that is 850 bucks and ear buds that can translate any language into english at the same time. >> the headphones sound cool >> how does it work? >> does realtime mean literally re realtime or -- >> is there somebody translating to you >> it's an impress serve edive n android never quite had that ka cache of getting people into the ecosystem, google launched their phones before but

. >> i used to love, of course, women of my and sean parker and cassidy brothers.ting was my love. he this is younger days. he was a teacher. he had all these great rock star but wisdom and cool, young teacher he is still in great shape. he does yoga every day. >> he is amazing. i used to dream in college would i go up to new york and remind me coming through and being in the party and getting to meet him. >> you ever did. >> no, i never d i would go to a party with the hopes. >> i met him. >> yesy was coming out of the museum of modern art. >> i work there. >> you work there. >> yes. >> in new york. >> yes. >> i'm coming out of there, it is pouring rain. he and his wife, waiting on a uber, this is before uber when you have a car service. so trudy and sting are standing on the corner, where my car pulls up, and it is pouring. i said, did you need a ride back to the hotel. didn't notice these were sting they were struggling. they said sure. get in the back of the car i looked over its freaking sting and trudy. i dropped them at a hotel. >> onlytunning. >> by the way

it was for sean parker.he one thing jonathan doesn't have access to that i have to have if he has to have a the -- a little that he just cannot even fake it. charlie: great to see you again. congratulations. ♪ is this a phone? or a little internet machine? it makes you wonder: shouldn't we get our phones and internet from the same company? that's why xfinity mobile comes with your internet. you get up to 5 lines of talk and text at no extra cost. so all you pay for is data. see how much you can save. choose by the gig or unlimited. xfinity mobile. a new kind of network designed to save you money. call, visit, or go to xfinitymobile.com. ♪ charlie: we are living in the midst of a podcast boom with the rise of mobile. more people are consuming content in transit. podcasts benefit from the power of audio, the most independent -- intimate form of media. "when guests are compelling and the conversation covers a complete drum kits, the hands of a clock disappear and i feel like i have enjoyed a secondhand human ex

. ♪ ♪ >>> welcome back peter thiel and sean parker are reportedly financing a secretive cancer fightingcalled 3t bio science raised more than $12 million in a massive seed round. the firm is working on ways to use the body's own immune system to fight off company the company is led by a company biology ph.d. student. >>> we're joined bay pioneer of immunotherapy research, max krummel is director of pathology. today he hopes to make -- some day make us allergic to certain types of cancer. what was the mmunotherapy -- >> a monoclonal antibody, a marker on t cells. >> as you deal with immunotherapy, i think about the immune system, and that is what makes it so complex. stuff tis t we have heard of the advances of mono clonals which were b cells then you have cytokines and all this other stuff is part of the immune system and it works together, right? >> but the key about mono clonals is they're drugs that are binding the surface of cells and interrupting the conversations immune cells are having with each other while they decide what to do. >> so how well is the function of t-cells underst

parker. when we think of the lone ranger, it is going to be clayton moore. when you think of james bond, it has to be sean connery. and when you think of the western historian, you think of paul hutton. it is my great pleasure to introduce paul to speak to us tonight. [applause] prof. hutton: i know it is so common to think of me and sean connery in the same way. [laughter] certainly my wife does. not. [laughter] i want to thank the buffalo bill center of the west. i want to thank jeremy and his excellent staff. this really has been a marvelous three days. the only thing i've really learned as i have aged is how little i know. and being around all these bright young scholars this week has certainly shown me just really how little i know about something i thought i knew everything about. it is wonderful new work and exciting new work. as a historian, one of the things that makes you get up in the morning and after hearing that introduction, all this stuff i have done, i understand why i am so tired, and it is so hard to get up in the morning. [laughter] but i certainly appreciate so much all that they are