of late amgen is down some 27% from peak. i think that's the opportunity one of two amgen charts.hart itself you can see they are down 27% from its peak just four or five months ago that sell-off is down to trend final chart. you are literally down to the penny to the well-defined uptrend in effect for the past ten years. it has bounced there before and we think it bounces there again. >> mike, what is your take >> obviously, one of the side effects of this stock's weakness has been the valuation -- certainly taking a look at price to earnings is getting down to low levels in fact, it's trading a little over 14 times right now, getting close to 10 year lows. just because the pe of a stock is low doesn't necessarily mean it is a great time to buy it sometimes it can be indicative in a cyclical that you are near an anticipated top in a cycle. but take a look at amgen and the range traded over time any 60 or 90-day holding period, your returns would have been 2% and 3% respectively and you would have been up about 63% of the time however, if you only purchased the stock when the valu

of late amgen is down some 27% from peak.e opportunity so one of two amgen charts here is the chart itself next chart you can see they are down 27% from its peak just four or five months ago but that selloff is exactly down to trend final chart. you are literally down to the penny to the well-defined up trend that's been in effect for the past ten years it has bounced there before, we think it bounces there again >> all right mike, what's your take >> yeah, so, i mean, obviously one of the side effects of the stock's weakness has been that the valuation -- certainly taking a look at price to earnings -- is getting down to low levels in fact it's trading a little over 14 times right now, getting close to 10 year lows. just because the pe of a stock is low doesn't necessarily mean it's a great time to buy it. sometimes that can be indicative, obviously in a cyclical that you're possibly near a top or an anticipated top in the cycle but just taking a look at a 10-year history of amgen and the range of valuations that it has trad

moderna, amgen and gilead makes up 20% of the index. to answer your question, each one of the three stocks that i mention vd their own specific story. i think moderna might have finally sort of maybe found its way through. obviously, that downgrade a few months ago didn't help then the merck news. a lot of things weighing against moderna, found its footing today. amgen sticks out to me like a sore thumb. >> this is trading at levels we last saw in the spring of 2020 i think ibb, if you believe in amgen, which i do, and oh, by the way, if gilead can get out of its own way, i think the ibb is interesting at these levels. >> ibb is less than 3% at that point and the difference between the two, of course, is ibb is market cap weighted. so you have the big heavyweights hold downing that index. but we highlighted the sbi because it gives equal weight to a lot of the holdings and, karen, if you wanted to play beta in biotech, that's where you would go because there is sort of a smaller companies in general. >> right they are smaller companies

you go back a couple nomonths ad moderna is at levels it should hold i think amgen is cheap >> jeff, you like ibb because it is not a basket level case do you like it itself as an investment >> yeah. the chart doesn't look great if failed at the february high down the 200 day i agree with guy, there are ones that look overdone i think it is a reasonable entry point. but regardless of the near term it's a great way to get diverse exposure to a corner of a market that has huge growth potential over time and you are not exposed to idiosyncratic names it is not like going all out on moderna before the big pop it has lagged over the last five years, but if you pull your lens back over the last decade, it has crushed the s&p 500. i think we are on the precipice of innovation in biotech so i think, yes, hold ibb. >> you can look at it as glass half full in that we haven't seen a draw down like this in years. >> i think constituents have a lot to do with this. before the drawdown, and we have struggled, but this is one of the best five-year charts if you take it all of the way back. moderna,

amgen and verizon are sliding to their lowest levels since early 2020 almost two-year lows verizon ist talking about sinking to the lowest levels, a 2% decline today you have to put that into context. it's near an 11-year low both wells fargo and barclays, the stock had eight positive days in september and not a single gain of more than 1%. alibaba got a temporary bump on a reuters report that the founder was spotted in hong kong today. there you can see it turning positive earlier now down just under 1% he's been largely out of view since the china crackdown started last year and shares are down 30% this year now time for a cnbc news update. >> here's what's happening the fda has taken no position saying two doses with enough to prevent severe disease and death. the fda staff also didn't take a position on pfizer booster shots, although they were approved >>> the day after columbus day, kamala harris telling native americans that the u.s. must address the damage done by european explorers to native communities. >> those explorers ushered in a wave of devastation for tribal nations, p

>> earnings next week, amgen and marriott long. >> nadine? >> sell a put, sell a call and mastercard 205, 225 >> see you next friday for more. >> "mad money" starts now. >>> my mission is simple to make you money. i'm here to level the playing field for all investors. there's always a bull market somewhere, and i promise to help you find it. "mad money" starts now >> hey, i'm cramer welcome to "mad money. welcome to cramerica i'm just trying to make you some money. my job is not just to entertain you but to educate and teach you so call me at 1-800-743-cnbc or tweet me @jimcramer. let's say you told me yesterday after it was a horror show at 4:00, that this market could finish in the black on a day when apple, amazon and starbucks got pummeled during the earnings period i'd call you crazy these companies are too big, too iconic, too important to the averages yet that's exactly what happened dow gained 99 points nasdaq edging up a nice end to the best october in six years, once again proving the only thing you need to fear about this month is

intel and amgen are the biggest decliners. salesforce up 2% now the yield on the ten-year following the auction last hour is trending lower so this morning when we reopened, we were more at the 1.6% mark 158 is the latest read there the vix is up more than 20% and that's been changing the market game how do you place your bets our next guest says there's no need to pick a specific style. here to explain is russ, portfolio manager of the blackrock global allocation fund where would you be allocated >> thanks, kelly i think the key right now as we spoke about in the past is to find companies that are profitable to find companies with earnings consistency, cash flow momentum and probably the fourth characteristics we're focusing on is pricing power. i know most of the, you know, narrative is about growth or value. the interesting thing is coming in to q4, they were about neck and neck they were both up about 19, 20% to the year. value's pulled ahead a bit in the fourth quarter, but i think we're at the point in the cycle where ec

gilead sciences and biogen and amgen.ee of the worst performing stocks within the nasdaq 100 perhaps, carl, perhaps, deeddei a move as people take stock in what is happening in biotech. >> we talked about this yesterday, some of the pandemic darlings losing a little momentum another stock i want to identify that just opened this week for trade and that is rent the runway it has now closed lower every day since that wednesday ipo it opened at $23 priced above at the high end of its range. but, look, now, it's trading below $19 a share. take a lookt a ipos more broadly. substantially underperforming the market here's the renaissance ipo index versus the triple q. cramer tweeted two, and then there's everything else. he'd stick with everything else. >> yeah, i wonder how to put that up against this really, i think, weird action in zendesk and what that says about risk and what that says overall investor appetite as we see some of the most successful companies in the market. apple, amazon dealing with supply chain crunch issu

the dow is still red only 39 points it is explained by the weakness in disney, amgen and united healtht week. as far as the s&p 500 growth is in the lead. the stock market is higher right now. fourth day of gains. technology, communication services are the top performing tech sec torsand then we have - tesla and amazon gap is also a big winner up 4.5% the nasdaq higher. big cap tech names working apple after the event. facebook microsoft. all higher ♪ >>> welcome to the "closing bell." i'm wilfred frost along with sara eisen and mike santoli. just in the red at the close for the dow but only by 35 points. s&p up the nasdaq up 0.8% consumer discretionary led the charge because of amazon and tesla for the most part and why the nasdaq led the charge today. disney the biggest drag on the dow after barclays downgraded the stock. coming up ben silverman on whether that's a warning sign including for netflix. lindsay bell with us and mark smith from wells fargo joins the conversation mike, one thing that we haven't touched on is the big mover again short end of the yield curve reacting people

i amgen fer casarian and i work here at san francisco international airport. 9/11 and he was able to see how his dog was able to relieve passenger's jitter. when we first launched the program back in 2013, our main goal was to destress our passengers however what we quickly found is that our animals were helping us find a way to connect with our pang. passengers. we find there are a lot of people traveling through the airport who are missing their pets and who are on their road a lot and can't have pets and we have come in contact with a lot of people recently who have lost pet. >> i love the wag brigade. >> one of my favorite parts is walking into the terminals and seeing everybody look up from their device, today everybody is interacting on their cell phone or laptop and we can walk into the terminal with a dog or a pig and people start to interact with each other again and it's on a different level. more of an emotional level. >> i just got off an 11.5 hour flight and nice to have this distraction in the middle of it. >> we look for wag brigade handlers who

i amgen fer casarian and i work here at san francisco international airport.e idea for therapy dogs got started the day after 9/11. an employee brought his therapy dog to work after 9/11 and he was able to see how his dog was able to relieve passenger's jitter. when we first launched the program back in 2013, our main goal was to destress our passengers however what we quickly found is that our animals were helping us find a way to connect with our pang. passengers. we find there are a lot of people traveling through the airport who are missing their pets and who are on their road a lot and can't have pets and we have come in contact with a lot of people recently who have lost pet. >> i love the wag brigade. >> one of my favorite parts is walking into the terminals and seeing everybody look up from their device, today everybody is interacting on their cell phone or laptop and we can walk into the terminal with a dog or a pig and people start to interact with each other again and it's on a different level. more of an emotional level. >> i just got off an 11.5 h

i amgen fer casarian and i work here at san francisco international airport.ea for therapy dogs got started the day after 9/11. an employee brought his therapy dog to work after 9/11 and he was able to see how his dog was able to relieve passenger's jitter. when we first launched the program back in 2013, our main goal was to destress our passengers however what we quickly found is that our animals were helping us find a way to connect with our pang. passengers. we find there are a lot of people traveling through the airport who are missing their pets and who are on their road a lot and can't have pets and we have come in contact with a lot of people recently who have lost pet. >> i love the wag brigade. >> one of my favorite parts is walking into the terminals and seeing everybody look up from their device, today everybody is interacting on their cell phone or laptop and we can walk into the terminal with a dog or a pig and people start to interact with each other again and it's on a different level. more of an emotional level. >> i just got off an 11.5 hour