it's not exactly alzheimer's alzheimer 's. not, as they say, expressed as a percentage, compared with dementia , this percentage of everything. percentage is all the rest is vascular dementia strokes. yes, yes, after strokes it can be associated with some kind of injury. this may be related to stress. it could be high cholesterol. this is a huge metal- so they say body weight, diabetes mellitus , the so-called metabolic syndrome. and this is also the path to dementia. that is, at this stage, i want to make such an exclamation mark because this is a sign of a healthy lifestyle. if a person works on himself, he understands what in his life prevents him from being healthy and engages in physical activity, eats properly, if he controls his health indicators, such as body mass index, cholesterol, sugar, blood and other indicators that are important for him, which affect the vascular manifestation, then, in principle, this dementia can stretch up to 120 years and slowly. as they say grow and practically. he adapts to it, or it grows

alzheimer's in this country.ure? i think the figure is 50 million. but set to - figure is 50 million. but set to rise exponentially in the next 20 to 30 is partly because of an ageing population. one thing on participants, i have sat with the participants, i have sat with the participants while they have received their infusion of this drug and really a tribute to them and all those involved in the trial because they have had these infusions every two weeks right through the pandemic. nothing stops them turning up pandemic. nothing stops them turning up every two weeks to have these infusions. real dedication. and some getting a placebo. extraordinary selflessness of the people who took part and without them because so many trials do fail, but this one really does look like a winner. albeit it has a modest beneficial effect. �* ., ., ., , albeit it has a modest beneficial effect. ., ., ., , , ,, effect. and how onerous process processes _ effect. and how onerous process processes the — effect. and how onerous pro

have alzheimer's. 30 million people around the world.umber is expected to increase hugely, isn't it? the alzheimer's drug could have profound significance. >> well, it could. it was tesd in people who had mild stage disease, not the full spectrum. the logic of testing in that population is it delays the time of when it arrives at the later stage of disease with greater disability. of course expansion of the drug into those other populations with more advanced stages would require showing that it actually benefits the patient's, more study would be needed in patients that have other stages beyond mild. laura: there has been controversy in the united states over alzheimer's drugs. is there a lesson to be learned about not rushing to improve -- two approved drugs? >> absolutely. it showed among other things the failure of medicare and cms to work together, getting back to that need to have a strategy on data. we also learned about the need to pay attention to process. to pay attention to conveningn advisory board and asking them questions t

lecanemab didn't stop alzheimer's...you started here. ..but over 18 months, it slowed its progression by about a quarter. this is so exciting because now we're getting results, the first results that are indicating that the drug is successfully treating the underlying cause and is slowing down the symptoms of cognitive impairment, and also the behavioural symptoms associated with alzheimer's disease. in alzheimer's, progressive damage is inflicted on the brain by the build—up of a rogue protein called amyloid. lecanemab works by clearing amyloid from the brain. david and his wife cheryl can't be sure if the drug is making a difference, but they're delighted to have taken part in the trial. when we first began this two and a half years ago, we didn't necessarily think it would help us, but we felt we were doing something and could help future generations. it's just a horrible, nasty thing. if somebody can slow it down and then eventually get it stopped altogether, you know, it'd be brilliant. at least half a million peopl

alzheimer's affects about 60% of them.is new drug, which won't be available until it gains approval from medicine regulators, will bring hope to many. here's our medical editor, fergus walsh. dementia is the most feared condition among older people, but mavis who is 88 is enjoying her retirement, such as coffee mornings, despite a diagnosis of early—stage alzheimer's. i don't feel old, i don't feel tired particularly. we enjoy life together, and i've got family which i absolutely adore and enjoy them. life, i think, is rather nice. mavis' short—term memory is badly affected, and she increasingly relies on her husband, rodney. what are you going to do with yourself today? i have no idea. you are going up to have an infusion at the clinic. oh, thank you. that's exciting. come on, rodney, let's get going. mavis is one of nearly 2,000 patients who took part in a pivotal trial of an alzheimer's treatment. so i'm just going to show you the hippocampus, i and that is where all our- short—term memory is stored. and what you can se

lecanemab didn't stop alzheimer's...here. ..but over 18 months, it's slowed its progression by about a quarter. this is so exciting because now we're getting results, - the first results that - are indicating that the drug is successfully treating _ the underlying cause and is slowing down the symptoms of cognitive - impairment and also the behavioural symptoms associated - with alzheimer's disease. david and his wife cheryl can't be sure if the drug is making a difference, but they're delighted to have taken part in the trial. when we first began this two and a half years ago, we didn't necessarily think it would help us, but we felt we were doing something and could help future generations. it's just a horrible, nasty thing because if you... if you... if somebody can slow it down, and then eventually get it stopped altogether, you know, it'd be brilliant. at least half a million people across the uk are living with alzheimer's — by far the most common form of dementia. lecanemab is designed to help those in the early s

a new drug is shown to slow alzheimer's disease in its early stages.describe it as momentous. and celebrations in melbourne as australia go through to the knockout stages of the world cup. it's 7am in singapore, and 11 pm in london where buckingham palace has issued a formal apology — following remarks made by a senior member of the royal household to a black charity founder — who said she was questioned about whether she was really british at a royal reception on tuesday. lady susan hussey is godmother to prince william — the prince of wales — and served as lady—in—waiting to the late queen. at a gathering hosted by the queen consort, lady hussey made comments described by the palace as �*unacceptable and deeply regrettable�* — and said that she had stepped aside with immediate effect. our royal correspondent nicholas witchell has the latest. buckingham nicholas witchell has the latest. palace yesterday afternoon. buckingham palace yesterday afternoon. a reception to highlight theissue afternoon. a reception to highlight the issue of violence against

now that would just, you know, if you get alzheimer's, you take the judge, you get rid of the alzheimer'ser like that. >> we're nowhere close to that. so we take small winds. is that fair to say where we can get them? we start somewhere. and the good news is there's 2 other drugs were waiting to see that. also look very promising. >> so we may go from 0 drugs to multiple drugs. and what we hope is that they'll be different approaches, different aspects of the disease that will be targeted and we could get to the day where people can live. well with alzheimer's or even mild cognitive impairment. >> and so we're raising the goal is just over a million dollars for the san francisco walk specifically. here's the map of the route of folks want to think about getting out tomorrow morning and helping the cause. but, you know, we're at about 800,000 right now. where does all this money actually go to? >> well, the reached the money goes for research as as we were just talking about really important to fund research, but also to fund care and support and services for those facing alzheimer's today

alzheimer's gradually destroys key areas of the brain involved in memory and understanding.in called amyloid, which clumps around neurons in the brain. the new drug lecanemab binds to amyloid, which prompts immune cells to attack and clear it from the brain. access to the drug could be severely limited, in part because specialist tests required to screen patients for amyloid or not widely available. but there will be a clamour for the treatment, which in the trial slowed cognitive decline by about a quarter over 18 months. lecanemab is not a cure. it can only help patients in the early stages of alzheimer's, but it is the first drug to convincingly slow cognitive decline, so that makes it a breakthrough against this relentless disease. doctors running the trial are delighted by the findings. this is so exciting because now we are getting results, the first results, that are indicating that the drug is successfully treating the underlying cause and it is slowing down the symptoms of cognitive impairment, and also the behavioural symptoms associated with alzheimer's disease. y

it can be early signs of alzheimer's. what are some of the symptoms of that that we should be looking out for? >> the initial sign of alzheimer's disease is difficulty with memory. then you have to look at it because -- whether it is something other people recognize. if you are losing -- if you are losing your keys because you do not remember having them, that -- it is really a memory problem. as it progresses, you forget how to do basic things and activities that -- you have difficulty remembering appointments and balancing a checkbook and that goes into more basic activities like keeping yourself clean and dressing. >> when you see a loved one having those symptoms, it might be time for a conversation? >> yes, but it is a very difficult conversation because -- it is really something. we are recommending here is annual memory screening. this is part of the national medicare annual wellness visit. it should be done. we need to educate doctors and physicians to do that screening. people do not want to deal with this measur

here depression also leads to the emergence of disease alzheimers.o so that alzheimer 's disease does not visit us? and, of course, as much as possible . work try to work even at retirement age, especially if your work is related to intellectual activity, yes, that is, in general, the tension of the intellect does not increase the blood supply to protein synthesis in the brain, what is memory, this is protein synthesis, right? eat, let your diet be varied, as many vitamins as possible, especially natural ones, should be present in your diet again, quit smoking in the brain. it was very small, very thin vessels. nicotine constricts these capillaries and interferes with the delivery of oxygen to cells. let your diet be rich in various foods containing the maximum amount of antioxidants antioxidants. they fight the aging process in our body. and in particular, it improves the metabolic processes of the brain. engage in vigorous physical activity. remember that when you and i move, muscles secrete substances that in the brain contribute to the formation

so, alzheimer's disease, was treatable? so, alzheimer's disease. we — was treatable? treatable? so, alzheimer's disease, we often say - was treatable? so, alzheimer's disease, we often say it - was treatable? so, alzheimer's disease, we often say it has - was treatable? so, alzheimer's - disease, we often say it has lagged 20 years behind cancer, first of all. we had to be able to talk about dementia and alzheimer's disease. and then we have needed to understand the biology in order to understand the biology in order to understand targets that we might be able to be able to identify. then we have a major problem that we need to get drugs into the brain, and then to show that they are working. so, this drug trial today stems really from work done by some of my colleagues, john hardie and colleagues, john hardie and colleagues at the ucl, 30 years ago. and we have been trialling these sort of approach for the last 20 years. so this really is a major step, that we are able to get drugs into the brain. clearly, amyloid has some effects on cognition, and so far, to do so r

lecanemab didn't stop alzheimer's...re. ..but over 18 months, it's slowed its progression by about a quarter. this is so exciting because now we're getting results, - the first results that - are indicating that the drug is successfully treating the underlying cause . and is slowing down - the symptoms of cognitive impairment and also the behavioural- symptoms associated - with alzheimer's disease. david and his wife cheryl can't be sure if the drug is making a difference, but they're delighted to have taken part in the trial. when we first began this two and a half years ago, we didn't necessarily think it would help us, but we felt we were doing something and could help future generations. it's just a horrible, nasty thing because if you... if you... if somebody can slow it down, and then eventually get it stopped altogether, you know, it'd be brilliant. at least half a million people across the uk are living with alzheimer's — by far the most common form of dementia. lecanemab is designed to help those in the early st

well, our family is experience alzheimer's. personally, i'm you know, my suffered with it for 10 years and succumb to 2 last year and so it's a cause near and dear to our heart. and so we just thought what a great way for us to give back as a family and see what we can do. using round pond is a platform. >> round pond estate. so tell me about that connection of being able to use. you're winery in order to honor him and all those whose lives have been lost as a result of this awful disease. >> that's truly terrible. and we're so excited. the launch of our new project. it's called honor and which means guardian or to show respect for. and so what our plan is is to showcase the stories and the photos of people, you know, including my dad, but so many others who have been touched by this disease our goal is to raise, you know, in the first year, to support the cause and do what he can to fight alzheimer's disease. we're looking at a picture we wear of of the wine bottle with all of those faces in the honor and >> who are those peop

lecanemab didn't stop alzheimer's...ust get you started here. ..but over 18 months, it's slowed its progression by about a quarter. this is so exciting because now we're getting results, - the first results that - are indicating that the drug is successfully treating _ the underlying cause and is slowing down the symptoms of cognitive impairment, and also— the behavioural symptoms associated with alzheimer's disease. _ david and his wife cheryl can't be sure if the drug is making a difference, but they're delighted to have taken part in the trial. when we first began this two and a half years ago, we didn't necessarily think it would help us, but we felt we were doing something and could help future generations. it's just a horrible, nasty thing because if you... if you... if somebody can slow it down, and then eventually get it stopped altogether, you know, it'd be brilliant. at least half a million people across the uk are living with alzheimer's — by far the most common form of dementia. lecanemab is designed to help

and here's dr susan kohlhaas, director of research at alzheimer's research uk.le having seen the media coverage and the people were taken incredible hope that this breakthrough would lead to more breakthroughs down the line and lead to treatment that will be widely used across the world, really. i think as you say, diagnosing alzheimer's disease is one of the most feared conditions in the uk and lots of people think it is an inevitable part of ageing and i think this result proved that it is not. and we can do things about alzheimer's disease through research and this result proved that it is not. and we can do things about alzheimer's disease through research and as we came to do through charity. regulators will now be working to ensure that potential side effects — such as brain swelling — can be made safe. our medical editor fergus walsh says the description of this as a "breakthrough" isjustified: it is an imperfect drug that is only modest benefits easily suitable for those in the early stages of the disease but it proof of principle that the underlying mec

he had to quit his job when he was hit by alzheimer's.e could no longer to -- no longer remember how to use his tools. >> could you get the broccoli out of the fridge for me? >> yep. >> he has taken part in the international trial of the experiment told drug designed by japan and the u.s. >> when we began this, we did not think it would help us. but we thought we were doing something, and could help future generations. >> it turned out the drug could actually help. the trial has shown that the treatment is able to slow down mental decline by 27% when diagnosed at an early stage. >> this is so exciting. now we are getting results, the first results indicating that the drug is successfully treating the underlying cause and is slowing down the symptoms of cognitive impairment and also the behavioral symptoms associated with alzheimer's disease. >> there have been concerns over side effects, which include brain swelling. two people of died -- have died while 14% suffered brain bleeds. scientists stressed that the same number given a placebo a

so the hallmark of alzheimer's disease. one of the hallmarks is the build up of 2 proteins on the brain called amyloid and how these kind of form the sticky packs that can be very damaging to the brain associated with these symptoms. the cognitive decline, like memory loss and confusion and changes in behavior. now what that kind of does is it contains antibodies that attached themselves to these am amola proteins and fuck them up to the bodies immune system. so the body to mean system comes along and breaks down the proteins and can go some way to destroying these plaques. and that's why we're saying that 2027 percent reduction in the unsaved of cognitive decline in this study. ok? but there are some concerns. yes, so there were more cases of beat on the brain and brain swelling in the trial of patients who tried the drug compared to patients, you just had a placebo. some research is the thing 27 percent. you know nothing to get wildly excited about the study only let to 18 months. so there's question marks about long term

alzheimer's is just a news. yeah alzheimer's is just a horrible disease .self grieving somebody who's standing right there in front of you. i mean, it's of course very sad that this is too late for mum, but incredibly encouraging that this research is coming forward . food inflation risen to forward. food inflation risen to 12.4. that is a record high since records began 17 years ago.the since records began 17 years ago. the british retail consortium says the figure is nearly doubled since october as rocketing energy, animal feed and, transport costs forced up pnces. and, transport costs forced up prices . the data also showed prices. the data also showed fresh inflation rose even higher. 49.3% with the cost of meat eggs and dairy soaring the highest for those of planning to eat a traditional dinner on christmas day this year, consumers are being warned of a shortage of british free range turkeys. the british poultry says half the turkeys being produced the festive season in the uk have already been killed in the bird flu. the uk have already been killed in

when he was hit by alzheimer's. he could no longer remember how to use his tools. raising her fossil career. could you get the broccoli out of the fridge for me please left. you. david is one of neely 1800 patients who have taken part in the international trial of the experimental drug designed by japan's. i say, in its u. s. partner biogen. when we 1st began is 2 and a half years ago, and we didn't necessarily think it would tell path arm, but we felt we were doing something and could help future generations. it turned out the drug could actually help the trail has shown that the treatment coldly canon mab is able to slow down mental decline by 27 percent. when diagnosed at an early stage, this is so exciting because now we're getting results. the 1st results that are indicating that the drug is successfully treason the underlying cause and is slowing down the symptoms of cognitive impairment and also the behavioral symptoms associated with alzheimer's disease. they have been concerns over side effects which includ

i decided to become a neuroscientist because my nan and several great aunts developed alzheimer's disease. this loss has made me determined to find a cure by any means. i'm fascinated by recent research that links diseases of the brain to microbes in our bodies. and i think this is an avenue that is just coming into its own in terms of research. microbes are tiny living things, smaller than the eye can see. inside the body microbes like bacteria, parasites, and viruses can cause any number of infectious diseases. so what would happen if we just eradicated all of the body's nasty microorganisms? what would the health of society look like? to answer that i want to know how microorganisms cause disease in the first place. so i've come to australia to meet dr. barry marshall. barry's groundbreaking research turned the world's understanding of stomach cancer on its head and won him the nobel prize in medicine. barry is a complete science legend. today barry is hunting a nasty microbe called helicobacter. this bacteria infects the guts of animals and makes them sick. - there are about 30 differ

according to estimates from the alzheimer's association.worth just learned is dr. chris t. purnell region at large for the american college of preventive medicine. this genetic predecision that he learned that he has. it's not a diagnosis, but would you describe it more as a strong indication this could happen, sore what's the sense? >> i think the easier way for everyone to understand it, if you have this risk, the gene, the risk for alzheimer's increases. 2% in that age group will develop alzheimer's. if you have one copy of that gene, that risk triples, if you have two copies, it increases 10 to% 15. >> listen, i come from, i'm particularly interested in the story, my grandmother her alzheimer's. i had a cousin who had early on set. other family members who i don't want to call out, whatever, had an issue with alzheimer's. if you're able to diagnose this early, from medication to take? things you can do to help knowing so you can get your affairs in order? do you know what i'm saying? >> i totally hear what you're saying. i'm a preventiv

the breakthrough drug shown to slow the progression of cognitive decline in alzheimer's patients at the well car budget. tina's come back is complete. they finished top of their group. after bt. ah hakim jeffries has been elected as the new democratic leader in the us house of representatives. he takes over from nancy pelosi, who serve for 19 years. it comes at a critical time for the democrats who lost their house majority in the midterm elections at 52 years old jeffries is relatively young, 6 years younger than the average age of those sitting in the house of representatives. he's been in the house since 2013 and has chair the house democratic caucus since 2019 jeffries had a significant role in the 1st impeachment of donald trump. he was selected as one of 7 house managers, presenting the case against the been president. he's the 1st black person to hold a top party, lead a position in the house or senate heidi joe castro reports from capitol hill. good afternoon, everyone. as an honor, this is the new face of house democratic leadership. younger and more diverse, 52 year old had ca

alzheimer's gradually destroys key areas of the brain involved in memory and understanding.nds to amyloid, which prompts immune cells to attack and clear it from the brain. in the trial, lecanemab slowed cognitive decline by about a quarter over 18 months. lecanemab is not a cure. it can only help patients in the early stages of alzheimer's, but it is the first drug to convincingly slow cognitive decline, so that makes it a breakthrough against this relentless disease. doctors running the trial are delighted by the findings. this is so exciting because now we are getting results, the first results, that are indicating that the drug is successfully treating the underlying cause and it is slowing down the symptoms of cognitive impairment, and also the behavioural symptoms associated with alzheimer's disease. you look nice and warm. mavis may have been on a placebo drug during the trial, but is now definitely getting lecanemab. she receives an infusion every two weeks at this clinic in surrey. now, i heard you had a big coffee morning this morning. _ oh, did i? her alzheimer's

your president, this new hope for alzheimer's patients. as for the 1st time, an experimental drug has been confirmed to slow mental declining sufferers. it's called the cannon map and it reduced overall cognitive decline by 27 percent over 18 months of the trial involving nearly $1800.00 people shows. it can also produce side effects, such as brain bleeds and swelling, while the benefits so far, small doctors of welcome the results as a significant step forward in the treatment of outsiders. you know, i've been waiting for this. we said that this approach might work 30 years ago. oh, you know, if you'd asked me 30 years ago how long it would take, i'd say 5 to 10 years. so for me it seems definitely momentous. i think for patients, it's a real step forward, a real step for trying to understand this with a paper stevens from a d. w science. welcome paper. so i have to emphasize this drug still in its experimental stages. but tell us why it's giving so much home. yeah, i mean one charity described as the fast we'll treatment option that coul

uh some good news and there's hope for alzheimer's patients. as for the 1st time, an experimental drug has been confirmed to slow mental decline in sufferers. the drug, la camara, reduced overall cognitive decline by 27 percent of 18 months. with the trial involving the 1800 people shows the drug can also produce side effects, such as brain bleeds and swelling. while the benefits are so far a small doctors welcome the result is a significant step towards a, a treatment of 4 outsiders. you know, i've been waiting for this. we said that this approach might work 30 years ago. and you know, if you'd asked me 30 years ago how long it would take, i'd say 5 to 10 years. so for me it's, it seems definitely momentous. i think for patience it a real step forward, a real step forward. australian dishonest receptacle stevens from d. w. science. welcome paper. so i have to emphasize this drug dealer in its experimental stages. but tell us why it's giving so much. hm. yeah, i mean one ad charity described there as the 1st real treatment option that could be

so a hallmark of alzheimer's is the build up of amyloid and how proteins in the brain . thus what causes these brain plaques is kind of sticky. plaques can be very damaging to the brain and associated with the symptoms like memory loss and confusion. so like animals actually targets the amyloid proteins that because it contains antibodies and the antibodies flag up the proteins to the bodies own immune system to the immune system can actually destroy them. break them down, begin to break down the plaques, and then there's this. yeah, and that's what causes the holton, the progression of the cognitive decline of 27 percent over 18 months. is what the research found. are there any doubts here? we understand that there are some of them, right. although there's, yeah, you mentioned these side effects in the trial of increased brain bleeds and increase dwelling of the brain in patients who tried the drug compared to patients who didn't. so there are concerns about his safety. some research is a saying 27 percent, you know nothing to get that excited about. and there are also

in the brains of alzheimer's patients. nearly $1800.00 patients around the world took part in a study which showed a 27 percent slow down in the deterioration of their cognitive skills over 18 months. but if approved, the treatment will be laborious and costly. put minister through bud infusions twice a month. and will also require major investment in screening for the disease to catch it sufficiently early. and at the moment we did up through kansas trance, regal spinal flit, testing for a from a lumber puncher. and that is, ah, we need to broaden access to ways in which we can have access to those kind of tasks. we also want to see a new techniques that are quicker and faster and potentially cheaper. for example, blood test, if 30000000 people around the world suffer without highness in itself, just one form of dementia. much difficult and costly work remains before treatments . let alone cures a widely available. but this is a hugely significant 1st step. harry faucet, al jazeera london, ah, it wednesday is world cup action, australia beat denmark, one know then a through to the ne

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tomorrow is the san francisco walk to end alzheimer's.eeing -- emceeing the event. you can donate to the memory makers team, or reggie, is it officially a team? do you have your own? reggie: i am with the abc 7 team. we are close to being number one. jobina: who are we behind? reggie: i am not sure. i am at $4600 and i am trying to get to $5,000. instagram, twitter, and facebook, so no 7:00 a.m. clip today, so see you >>> good morning, america, for our viewers in the west. breaking news. a new show of force from north korea. the u.s. and south korea respond overnight. tensions escalating. south korea scrambles fighter jets after north korean warplanes were detected near the border. this as the u.s. and south korea extend joint exercises. >>> four days to go. both parties bringing out their heavy hitters ahead of the final votes in the midterm elections. former president trump campaigning in iowa overnight. vice president harris and hillary clinton in new york as president biden plays defense in california and new mexico. this morning, the

>> we all know someone with alzheimer's.s doesn't turn out to be the answer, is there more in the pipeline? >> there is more in the pipeline. they are a different -- many of them are a different class of drugs than this one. if this one doesn't work out the way we hoped, there are others in the pipeline. it will take years. ana? >> elizabeth cohen, thank you for the reporting. >>> william and kate, the prince and princess of wales, are in boston today. it's their first u.s. visit with their new royal titles and their first time on u.s. soil since prince harry and meghan markle moved to california for their private life. will and kate will take part in the earth shot prize award ceremony, the initiative william founded to tackle environmental challenges. they'll also visit the mayor of boston during their three-day visit to learn how the city is tackling climate change. >>> thanks so much for being with us. that's going to do it for us today. i will see you tomorrow. as always same time, same place. until then the news contin

jackie: this mon he alzheimer's awareness month.iving for alzheimer's and dementia patients. joining us a leading supporter of the organization, venture capitalist, pioneer, founder of apex partners, alan patricof. great to have you on. alzheimer's around dementia touch so many people across this country. it is so difficult for families that are struggling to be caregivers. tell me a little bit how you got involved in caring kind and your own struggle? >> well my wife passed away about almost two years ago after, during the alzheimer's for almost 12 years. the first eight or nine were not that bad. we managed to survive but the last three were very, very difficult. she lost her speaking and a lot of other functions. and i heard about caringkind and joined a support group which met every other week for hour 1/2 with eight or 10 other people who had different types of problems with neurological diseases including alzheimer's and we shared each other's stories with each other. i used caringkind to recruit a caregiver. i sent my wife an

one is obviously alzheimer's the other is obesity both of these newly create $$10 billion-plus categories i wonderge generalists, drug prices discussions addressed especially. >> we've got to leave it there appreciate you joining me. >> thanks so much. >> thank you very much. >>> got bitcoin. other crypto stabilizing a bit after a wild week and weekend of ftx headlines. many losers in the ftx downfall, of course, our next guest see as clear winner joining us, reiterated a bull case for coinbase. market is not taking this as a bullish sign for coinbase. why do you disagree? >> yeah. so last week was a week that for the crypto markets, some time i think put on a note today trying to gauge early read-throughs of how the ftx bankruptcy impacted broader centralizes exchanges across the market. we saw coinbase has taken early share along with some other regulatory compliant players in the united states like gemini and kraken i think when you look at that contrast to some of the global players that are less transparent, that, know, similar to sort of, not say ftxs, but offshore operating -- you

alzheimer's is sadly a hope-free zone. there hasn't been a lot of hope in treatments out there.going after the gunk in brains of people who suffer from this, is that at least a promising path? >> sure. that is a promising path. this is a monocolonial antibody, others out there as will, there was one that came out last year, and there was a lot of hope for it. the hope didn't quite pan out. it's really not being used terribly widely. however, there are hundreds in the pipeline. some of those work differently. they're different classes of drugs. the hope is those might be even more promising than these. >> so many people suffering out there, and so much money and research going into this. hopefully we consolidates get that perfect match and cure at some point. elizabeth cohen, thank you. >>> well, up next, russian lawmakers passing new laws that crack down even further on the lgbtq community. why one russian couple is defiantly sharing their love for the world to see. i'll speak with one of them, straight ahead. new science shows it gets in between teeth to destroy 5 5x more plaqu

they also don't know very much about alzheimer's.that maybe the mansion is just something is a normal consequence of aging, which is not it's a disease. so we need to find better ways to educate the population to educate your listeners. answer their shoes, to be very inclusive and to try to encourage them to get enrolled in our study because we can't find pop yet. we can't find medications that are really going to work on the black and latino and asian populations unless we include people from the black, latino and asian populations in our studies. is that simple, right, doctor? and, you know, i do want to point out some of the stats to that. it that dementia does appear to disproportionately affect people. >> from communities of color. i do want to ask you one last question in the remaining few moments we have here. how can people learn more about this study and sign up to participate? >> well, they can. they can go to the ad. the website is called the alzheimer's disease neuroimaging initiative and the ad and i and they'll get more

the new dragon alzheimer's experts say is a momentous development.own to slow down, but not to kill, alzheimer's and people in the early stages of the disease. earlier my colleague spoke to david cox, he was diagnosed with early onset alzheimer's about ten years ago when he was 65, she asked him about when he was 65, she asked him about when he first got the news? it he was 65, she asked him about when he first got the news?— he first got the news? it was enterin: he first got the news? it was entering the _ he first got the news? it was entering the shop _ he first got the news? it was entering the shop in - he first got the news? it was entering the shop in the - he first got the news? it was - entering the shop in the system. how did it come about in the first instance? what led you to that first appointment with your gp? it instance? what led you to that first appointment with your gp?- instance? what led you to that first appointment with your gp? it was a combination — appointment with your gp? it was a combination of— appointment with your gp?

. >> it is not going to save the person who you love who has alzheimer's now. the early stages of alzheimer's between ages of 50 and 90. some got a placebo and some got the drug. the ones who got the drug saw a 20% slower rate of cognitive decline and found that amaloid levels were lower, those are the plaques. those two things, is that enough to make a difference for someone with alzheimer's? first of all, it took 18 months to see these improvements. would you see a difference? would your grandfather, grandmother, mother, father, would they be different? would they feel better? would you notice a difference? would they notice a difference? is it worth it considering this risk i'm going to tell you about and this is a big, big issue. they found that folks who two the drug were more likely to have side effects. 17% had brain bleeding, 12% had brain swelling. >> that's a high percentage. elizabeth, thank you very much. for anyone interested you can go to cnn.com to find out more there. >>> this morning the founder of oathkeepers has been found guilty founder of o

do you have alzheimer's in your family? >> it does not run in mind.his is a good reminder to think ahead and talk to a doctor. even if you do have it running in your family, get it checked early. >> it is a devastating disease and really heartbreaking to know that is coming for you. it is something we have to deal with in our family. we start seeing the effects early. there is not a lot you can do about it. alzheimer's organizations and research for that, it really helps so many people. >> i like the fact that he kept that in there, though, just to bring awareness. >>> hello from the vegas side. one of the most critically acclaimed artist in the world just made her sin city residency debut. >> [ applause ] >> >> i am not going to lie. i am a little jealous. adele kicked off her stay at caesars palace this weekend. this started after a nine-month delay. she apologized to fans. among those in attendawetim cook , the ceo of apple, james corden, and our producer, who got this video. >> i was thinking, did he shoot this one? how amazing. >> they have been

. >>> tonight, we have important news on alzheimer's. a new drug and results coming in from patient trials in the early stages. and what researchers are seeing already. this is promising, so, will the fda act and when? >>> prince william and princess catherine here in the u.s. tonight amid the headline back home in london at buckingham palace. the resignation tonight. what a guest was repeatedly asked. >>> and back here at home, celebrating a beloved singer and songwriter behind some of the biggest hits of the 1970s. >>> and the message just in tonight from stevie nicks. >>> good evening and it's great to have you with us here on a very busy wednesday night. and we begin tonight with the deadly tornado outbreak. more than 30 reported tornadoes already tonight, 11 of those tornadoes confirmed in just the past 24 hours. many hitting during the night. a mother and her 8-year-old son did not survive. this tornado right here, one of the ominous sights sees seen. families sorting through the damage of their homes in mississippi today. rescue t

and researchers hail of breakthrough in the treatment of the early stages of alzheimer's. ah, so we begin in the us where a democratic member of the house of representatives have elected had keen jeffries as their new party leader. he is the 1st black person to hold the ro, jeffries will take over from nancy pelosi, who served for 19 years. his leadership comes at a critical time as the democrats lost the majority in congress during the mid term elections. id show, castro, join me now from capitol hill. heidi democrats have a new leader in the house. who is hecky jeffries. that is a name that we will have to be saying for a long time, cyril, as he is now, the new leader of the democrats in the house of representatives. he is a 52 year old congressman from new york. he describes himself as a pro progressive black representative, and he has strong ties with a democratic establishment as well. this is a moment that had long been seen coming. jeffries had been serving in another leadership role in the u. s. house since 2019 and his election that just happened minutes ago was u

you have an increased risk of alzheimer's disease. >> hm. how much higher?ly somewhere between 8 and 10 times higher than that of someone in the general population. >> yeah, right, okay. i don't know, you're constantly thinking you're going to live forever. especially as a young individual. and then to all of a sudden be told, oh, this may be the thing that might take you out was like, whoa. >> but it's my belief that if we take every step possible, we can reduce your risk to that of anyone else. this is going to motivate you to take steps today that most people your age would never think about until they're in their 50s or 60s. >> sure. sure. i've spent most of my life paying very detailed attention to my health and wellness. but i've never really focused on the health of my brain. this news changes things. >> reporter: after learning about his increased likelihood of developing alzheimer's, 39-year-old hemsworth says he'll be taking a break from hollywood for a while, going home to australia to spend more time with his wife and three children, embracing th

the times leads on new hope for dementia patients as a drug proves to slow alzheimer's for the firsttory. and just above a picture of gareth southgate and marcus rashford there after winning 3—0 against wales in the world cup. the i also has the three lions embracing but leads on the news that uk christians are a minority for the first time since the dark ages. "the curse of crypto" — the metro reports on a russian billionaire killed in a helicopter crash, making it the 3rd high profile cryptocurrency tycoon to die suddenly in a month. banks set for release from ringfencing rules in drive to free competitive spirit — that's on the front of the financial times. the mirror leads on the england triumph over wales highlighting marcus rashford's joint top goal—scorer at qatar. and the guardian also reports on the clinical trial that has confirmed the drug that slows congnitive decline in patients with early stages of alzheimer's. telegraph leads on thousands of ambulance staff set to strike for the first time in 30 years. we will start with two versions of the daily mirror. first the engl

who support those who are living with alzheimer's.his is going to make a huge difference. there are really a lot of great scientific advances that have been made over this past year. i am hopeful. kumasi: this is amazing. i remember when we were sitting here and you said you had $400. i was like, we need to get it up, raise it up. and people responded. reggie: u.s. to -- you pushed me. kumasi: you asked if we should raise the limit and we did. people will give more than that. companies will make -- will match donations. like disney matched mine for the 10k. 10k. reggie: i'm something for for everyone who supported this year. san jose sharks in the olympics. kumasi: let's take a look outside. outside. this is they would this is what voting yes on prop 31 means. yes on 31 ends the sale of candy flavored tobacco products. yes, stops big tobacco from targeting our kids. yes, protects kids from nicotine addiction. vote yes on 31. this is what voting yes on prop 31 means. yes on 31 ends the sale of candy flavored tobacco products. yes, stop

. >>> november is alzheimer's awareness month. 1 in 3 of all seniors die with alzheimer's.

for alzheimer's.imer's. so, not all doom and so, yes, it is not all doom and gloom. we're back a moment. yes, i love this part of the show where we go into the terrifying world. my inbox gbviews@gbnews.uk , loads of you gbviews@gbnews.uk, loads of you have been getting in touch. your thoughts on striking workers. lots emotive to this lots of emotive to this occasion. got your rail occasion. you've got your rail strikes, electric strikes strikes, the electric strikes sector people going sector one college people going to post—disaster sinking. to strike post—disaster sinking. and big for me is and the big one for me is nurses. i'm going to work because, have because, by the way, have apparently voted to strike just before will get you before i came on. i will get you the that very, very the detail that very, very shortly. but yes, nurses, of course, will going on strike course, will be going on strike on 15th. on the of on the 15th. on the 20th of december. it's so december. and it's so controversial .

yes, a serious problem, how acute is alzheimer and dementia in a nutshell, and do the elderly themselves relatives understand that this is a disease? is there a huge problem here? why because uh old man? does he begin to quietly hide his features? yes, with us he hides the fact that he forgets the keys. yes, but he tries, for example, to determine the place, which he clearly knows, that i put the keys there, that is, he puts some kind of markers there, because he understands him memory problems. this is not always seen next of kin. they can live separately for various reasons, but they can, for example, notice that the psychology of a person is changing. and here we have to start. as they say look closely. secondly, i really provoked the development of these cognitive changes and the progression of the so-called ones. that is, it was such a trigger for the progression of dementia. this decrease in physical activity is a psychological factor that constantly weighed down on them plus. naturally, people isolated themselves, and relatives, for example, they did not always communicate, that i

research shows a reduced alzheimer's symptoms by 27%. patients with early signs of the disease showed less cognitive and functional decline. that's according to the new england journal of medicine which published the results just today. drugmakers say they will apply for fda approval by march. this drug is different than the controversial one the fda approved last year. ama: still to come, marking their memory. the meaning behind these messages being painted in the south bay. a royal visit abroad. prince william and princess kate's plans for their trip to the u.s. tomorrow. the world cup business boom. see the kind of patriotic passion flowing to local bars and restaurants. dan: here's a look at what's ahead tonight on jimmy kimmel live right after abc7news. >> thanks. on this giving tuesday, i'm giving you a show. bicarb, you mean chop beyond recognition. >> a civil war surgeon in those movies. that leg is going to have to that leg is going to have to come off k detect this: living with hiv, i learned i can stay undetectable with fewer