brian kobilka. he and a duke scientist won the prize for their ground breaking discoveries of cell proteins. it could lead to the development of better medications. dr. kobilka is a professor at stanford school of medicine. >>> it is a short week four days for some people out there. so let's check in with sal and see if that is having any impact. >> mike and pam we didn't have a lot of -- we had a lot lighter commute. tuesday has been slow. and today we'll see what happens. let's go out and take a look at what we have on highway 4. it looks kind of typical. it will be a little slow already in antioch as the early crowd gets on the road. it's not too bad in bay point. if you drive to the bay bridge toll plaza it's also still light. usually we hit a crowd here at 6:15 or so. and the morning drive in san jose area that still looks good if you are driving on 101. no major problems on the 101 or 280 getting to the airport. across the bay interstate 880 that looks good. 5:37 let's go to steve. >> thank you

professor brian kobilka shares the prize with duke university professor robert lefkowitz for their work on g protein coupled molecular. >> from neuropsychiatric disorders to metabolic disorders like diabetes cardiovascular disease. almost any disease you can think of. even cancer. >> reporter: professor kobilka said he missed the first phonecall at 2:20 this morning and thought it was the wrong number. fortunately they called back. they will split the $1.2 million prize. now stanford is holding a press conference later this morning at 10:00 a.m.. and that will be on the campus of the school of medicine. reporting live in palo alto matt keller. >>> all right we are continuing to follow that developing news on the bay bridge unfortunately it looks like a mess. let's check in with sal. >> that is right. this crash that has been reported here was reported just after or just before 6:00 here westbound bay bridge on the incline section still has at least one lane closed here and traffic is squeezing by. now if you are trying to get to the bridge, this will mean a big backup at the toll plaza.

brian kobilka is a professor of molecular physiology.they won the prize this morning for ground breaking studies of proteins that allow body cells to respond to signals from outside. >>> now an update on the story we've been following all morning. several businesses are damaged after huge flames swept through overnight. it happened on alavodo boulevard one firefighter cut his hand while fiting the flames. crews had to use so much water to fight the flames they unintentionally formed a small lake. it began in a corner business and destroyed ten businesses and took out a chunk of the roof. investigators are trying to figure out what started it all. >>> in richmond a lightning strib could be to blame. it happened near the richmond parkway about 2:15. a palette manufacturing plant caught fire. mostly wood was burning so firefighters say there was no need to put out an alert. firefighters are still looking into the exact cause of that fire. >> very good news for san francisco sheriff ross mirkarimi. he will be keeping his job. that news offic

brian kobilka is a professor of molecular and cell physiology at stanford.and his colleague were honored for their studies of cells that open new fields of medical treatment. >> i guess i wasn't exactly sure if it was real to begin with and i think everybody has that response. but i was extremely happy. [ laughter ] >> as a professor can be. on monday ucsf professor shinya yamanaka won the nobel prize in medicine. >>> an east bay teenager has a closet like no other filled with thousands of pieces of clothing to give away. cbs 5 reporter sharon chin introduces us to this week's jefferson award. winner. >> it's a nice athletic jersey. >> reporter: like many teens laura graham of oakland is hung up on fashionable clothes but not just for herself. >> i've learned that small things can become big things. >> reporter: the 16-year-old junior at bishop o'dowd high school collects donated clothes through her nonprofit "1 closet" and she has given away more than 5,000 pieces of clothing to about 900 teenagers in the last year. >> and there's so many people cleaning ou

. >>> brian kobilka got the call from sweden about 2:20 a.m. that he won the nobel prize. he's a profess at stanford school of medicine and won the prize for ground-breaking discoveries on cell proteins that have helped scientists develop better medication e share urs the prize with duke university professor with robert lefkowitz and he says he already has plans for the money. >> the kids. they don't make that much money. you don't know what's gonna happen in the future. you want to be able to have something to leave to your children. >> yeah, it's icing on the cake. we never work for the company. it's icing on the cake. >> this is a wonderful day -- >> he also had a chance to talk about his work during a press conference at stanford this morning. >>> the hopes of another bay bridge world series are still alive and so are the bay area's two teams in the playoffs. >> rolling and it's caught! >> an error by the cincinnati red led to a giants ago extra- inning victory. the final was 2-1 in ten innings. the giants edged the reds 2-1. game four starts at 1:07 this afternoon pac

brian kobilka is a professor at stanford university of medicine.spoke with kcbs radio this morning. >> i believe it's in part because the proteins that we study -- d protein couple recenters are so important in so many aspects of normal health. >> he and cowinner robert lefkowitz were honored for studies of proteins that let body cells respond to signals from the owe side. kobilka said when he got the call this morning he thought it was a joke. >>> several schools in pakistan closed in protest today over the taliban attack on a 14-year- old girl. she is hospitalized in intensive care at a military hospital in peshawar where doctors removed a bullet from her neck. she has been blogging for the bbc about life in the war-torn country, she became an outspoken critic. taliban in pakistan. doctors are optimistic that she will recover >>> a republican led house committee will hold a hearing today on diplomatic security in libya a month after the deadly attack at the u.s. consulate in benghazi. california congressman darrell issa is chair of the house over

and this year's nobel prize for chemistry has been won by two americans, robert lefkowitz and brian kobilka. it is hoped that their work could ultimately produce medicines that have fewer side effects. now to twist in the case of the punk group. one member of pussy riot walked free today, but two of her colleagues are heading to a penal colony. they performed a song in the cathedral, mocking vladimir putin. >> she was free, but she didn't get far. yekaterina samutsevich was mobbed by supporters and journalists. but she was soon in the arms of her father. , but i feel bad for the others who did not get out. >> in court, some would say that the two-year -- in court, her setnece -- her sentence was commuted. the other two will be sent to a prison colony. she says, open will we have been jailed for our political beliefs -- she says, "we have been jailed for our political beliefs. ieven if we are sent to siberia, we will not stay silent." then again, they never have. it is this stunned which put three of them behind bars. they besieged the virgin mary to rid russia of vladimir putin. in court to

. >> brian kobilka, who shared the prize, says he hopes his development will spur the creation of new drugs. >> i hope we can translate these discoveries to develop safer, more effective drugs, and more economically developed drugs. >> the nobel prize this year is worth about 930,000 euros, to be split between the winners. the actual price ceremony will take place in december on the anniversary of alfred nobel's death. >> we will be back in just one minute's time with more on news of tensions in the balkans. >> we will also look at the frankfurt book fair and some celebrities who dropped in for it. stick around. >> welcome back. we turned our attention now to new tension in the western balkans, an area of bosnia and croatia where thousands of families live off the land, which is now under threat. >> the row has erupted along the river that flows through both countries. farmers are angry about plans to tap the system for new hydroelectric power systems further upstream. >> not only could it harm farming communities, the world wildlife fund has warned the government of bosnia and croati

robert lefkowitz from howard hughes institute and brian kobilka won the prize. they have independently studied how human body cells can sense their environment and discovered that a family of proteins later named g-protein coupled receptors, send signals to the cells. >>> turkey's military commanders are wrapping up their reinforcements along the border with syria. they've sent at least 25 more fighter jets to the area. the build-up of troops and weapons is adding to fears that the fighting in syria could escalate into a regional conflict. turkish forces have fired artillery into syria for six straight days now. they're responding to mortars that have come from the syrian side. the tension at the border began when a mortar fired from inside syria hit a turkish town. five civilians died. turkish military commanders say they've deployed 25 f-16 fighter jets to a base near the border. the military's also reinforcing its troops and moving gun batteries to the area. turkish officials say syria's military and rebel forces are engaged in a fierce battle near the border

brian kobilka is a professor of molecular and cellular physiology at stanford university school of medicine. he and cowinner robert alefkowitz were honored for studies of proteins that let body cells respond from the outside. half of all medications act on g protein couple receptors so they hope the research will lead to drug improvements. >>> a republican led house committee will hold a hearing on diplomatic security in libya a month after the dead will attack at the university consulate in benghazi. california congressman darrell issa is chair of the government reform committee and says the state department ignored pleas from diplomats in libya to increase security prior to the attack. >>> here's a look at the south american version of the running of the bulls. this amateur bullfight in colombia is known as [ speaking spanish ] alcohol infused fans are invited to jump into the ring and play matador. many participants is it died over the years but 2012 turned out to be a good one at least for the humans. 19 were injured though. >> that's a head shaker. >>> jerry sandusky is expected to fil

brian kobilka and his partner began their work on protein receptors in 1968. about half of all medications act on these receiptors. so learning about them has allowed pharmaceutical companies to develop better drugs. >> stanford has been a really remarkable place. i'm not really sure how i managed to land here, but i did. as i was telling someone this morning, i think it was the only place that offered me a job. >> he said he got the phone call at 2:30 this morning and five committee members passed the phone around, congratulating him. he said when five people talk to you in swedish accents, you realitize it is not a prank. >> no, not a prank at all. >>> and seeing that hail out there today wasn't a prank either. jeff ranieri joins us now. still a little bit of stormy weather out there. >> that's right. we're continuing to track what was a very dangerous thunderstorm cell moving across the south bay this afternoon from about 3:00 to just about 5:00. again, the past couple of hours moved from gilroy. held up all the way south to los gatos. and right now we're f

robert lefkowitz of duke university and brian kobilka of stanford are being honored for discovering theinner workings of receptors that allow cells to respond to chemical messages.. such as adrenaline rush. the nobel prize committee says about half of all medications act through these receptors. their research is helping to develop better drugs to fight diseases like diabetes, cancer and depression. >>next the undercover investigation into the mistreatment of dairy cows in the midwest and the major company selling their products. we're live on the story. and later in lunchbreak: a preview of this weekend's oyster fest. how to properly shuck an oyster with the chef from shaw's crab house! that was me... the day i learned i had to start insulin for my type 2 diabetes. me... thinking my only option was the vial and syringe dad used. and me... discovering once-daily levemir® flexpen®. flexpen® is prefilled. doesn't need refrigeration for up to 42 days. no drawing from a vial. dial the exact dose. inject by pushing a button. flexpen® is insulin delivery... my way. levemir® (insulin detemir [

. >>> stanford university professor brian kobilka won the nobel prize. >> i am being recognized for work and that is unusual. >> the call came in about 2:20 a.m. this morning. he spoke to five members of the committee who congratulated him. he already has plans for his half of the $1.2 million prize. >> scientists don't make that much money and you don't know what will happen in the future. you want something to leave to your children. >> icing on the cake. we never work for the money. >> he had a chance to talk about his work this morning. he shares the surprise with robert lefkowitz. their work could help with the development of more effective drugs. >>> hundreds of people turned out to find treasures today. the vehicles were auctioned off as governor jerry brown's plan to eliminate waste. some say it doesn't cost much to fix them up and turn a profit on it. >>> a stolen car found in seattle that is connected to the killing of a mother in contra costa county. coming up, the crash with seattle police and the action investigators are taking tonight. >> first a rescue, now rehabilitation,

and the other one is brian kobilka from stanford university. the men study how cells respond to outside stimulus. >> that's scientific. >> >>> when was the last time you checked facebook or twitter. you could be addicted. we'll explain ahead. >> i know that's one thing i do not have a problem wnchts you do not >>> and the holiday shopping list for the super rich is out. find out what a whole lot of money can buy you >>> and game 3 of the series with the card numbers the weather is holding up. your forecast from tucker ahead. plus, stick around. nats jen raw manager mike rizzo joins us live at 9:45. can you feel it? n you feel it? pamela howze: it just seems like such an... infringement on our lives. how dare they step into my life that way. it's none of their business. he's trying to restrict us, again. he's taking us backwards. george allen is the last thing we need in washington. anncr: the democratic senatorial campaign committee is... responsible for the content of this advertising. >>> can't get enough of facebook or twitter? turn out soc

. >> it is our pleasure to be joined by brian kobilka. a big-time congratulations. >> thank you, thank you. >> can you put it in layman's terms, professor, what exactly do you do? so we can understand on a level so we can be even more impressed. >> okay. this is always a tough one. my research is on a large family of proteins that sit on the surface of cells, the membrane of cells. they recognize various hormones and neuro transmitters. i guess the simplest example is a beta receptor on a heart cell will respond to the hormone adrenaline by increasing the strength of contraction or the rate of contraction. so it transmits these receptors. these receptors transmit this across cell membrane. >> what does that allow you to do? >> well, because these receptors regulate so many functions in the body, they're very important targets for a number of drugs. for a broad spectrum of diseases including different neuro psychiatric disorders, meta bolic disorder, even po tell chully, potentially they could be important in cancer therapies as well. they

brian kobilka is a professor of molecular and cellular physiology at stanford university school of medicine. he and cowinner robert lefkowitz were honored for studies of proteins that let body cells respond to signals from the outside. kobilka spoke with kcbs radio this morning. >> well, i believe it's in part because of the proteins we study are so important in so many aspects of normal health. so most of the hormones and neurotransmitters in the body work through these proteins. >> kobilka says when he got the call this morning informing him that he won he thought it was a prank but it was not. >>> several schools in pakistan closed in protest today over the taliban attack on a 14-year- old girl. the girl is hospitalized in intensive care at a military hospital in peshawar where doctors removed a bullet from her neck. she had been writing a blog for the bbc about life in the country and is an outspoken critic of the taliban in pakistan. doctors are optimistic that she will recover. >>> 6:20. that california man behind that anti-muslim film linked to the middle east violence is back in cou

and brian kobilka, who worked with him at duke before moving to stanford university's medical school. lefkowitz spoke by phone to a stockholm news conference, and said he didn't realize at first that the nobel committee had called. >> i must share with you that i wear earplugs to sleep, and so my wife gave me an elbow, call for you, and there it was, a total shock and surprise. >> sreenivasan: lefkowitz said the call was legitimate because as he put it, "when five people with convincing swedish accents call you, then it isn't a joke." a privately owned company notched a new first in space today. the space x cargo capsule named "dragon" docked at the international space station. it's the first of 12 such flights under a contract with nasa. astronauts on the station used a robotic arm to grab the unmanned capsule. "dragon" will stay docked for 18 days while the crew unloads almost 1,000 pounds of food, clothes and experimental gear. the capsule will then return to earth carrying medical samples and research material. wall street is now on a three-day losing streak. stocks fell again tod

another winner is brian kobilka from stanford university. the men worked on how the body cells respond to the environment. >>> toyota announced a massive recall involving millions of its vehicles. we have the details coming up next. >>> and another warning about a safety feature on your car that could be a fake. >>> and we are heading back to the ballpark. dave ross is standing by with two special guests >>> and as we take you to the break live, we get the lateness traffic from tucker and july. [ barack obama ] i'm barack obama, and i apapprove this message. [ female announcer ] he says... president obama and i both care about poor and middle-class families. [ female announcer ] but this is what the budget plan mitt romney supports actually does. more huge tax breaks skewed to the wealthy. while cutting nearly eight hundred billion from medicaid... even though middle-class families rely on medicaid to help loved ones cover nursing-home care. and it helps parents support children with disabilities. if mitt romney really "cares," wouldn't we s

. >>> robert lefkowitz and brian kobilka won the nobel prize in chemistry.arted their research back in 1968. >>> head of a large resort company tells his 7,000 employees their jobs are at risk if president obama is reelected. westgate resort david siegel sent a message in the e-mail which does not mention mitt romney. he said if he or his company has to pay any new taxes, he will have to cut jobs and benefits at his company. >>> north carolina man says he is blessed to be alive, following this hit and run accident. it happened while sean lewis was on his way to work and while he doesn't remember being hit, he does remember what happened next. >> i remember waking up. i was bleeding. my hand was all messed up. my leg was messed up. could have helped me out some way. didn't have to leave. i know god had my back. that's all i know. god was looking out for me. >> well, somebody was. lewis, who amazingly walked away, is now temporarily out of work. no arrests have been made in the case. >>> we know her as a political wife and mom. today, ann range of motiomney c