let's get back to gene gene, howdo you grade the quarter?, melissa, i'm going to lower my grade from a "b" to a b minus. deidre really hit at the end there, her last comment. specifically, keep in mind for 2016 and '17, amazon was growing investments in their warehouses by 30% year over year, sales only growing at 20%. 2018 they benefited because they basically built this infrastructure that had a positive impact on margins this comment that caused the lowering of the grade is more muted margin expansion this year that's a key part of the story i would say the scoreboard is broke when it comes to amazon. amazon has 3 billion in operating income that's one-sixth of what apple is yet amazon has a bigger market cap. so i had to factor that into my grade. >> all right, gene, thank you as always for your analysis gene munster >> can i ask gene a question. >> go ahead. >> i know we've got to go. last time we established a b -- >> b plus i thought. >> what would a b minus -- >> you're not eating you're not going out of the house. you're doing nothi

phil lebeau in chicago let's quick low check in with gene munster gene, what's your grade for tesla?in the middle of the asking a question on a call here but the simple takeaway is very optimistic i think investors have a tough time believing his optimism. if you take it at face value about their demand equation, pickups come in the summer and the unveil and profitably i think that it's room for optimism for the next year and two years. >> we'll let you get back to the call, gene, sorry to interrupt. >> back of the line now. >> i know. >> terrible. >> this call is a really important call all right. he's still talking that's good news so what do you think, guy? >> i think 300 or 302, i think you're smack in the middle of a very established range the last two and a half years this level you're flipping a coin i'd rather wait for the pullback somewhere between 260 and 280 to buy it than to flip a coin here. >> you know, it's interesting because we were talking about positioning. sentiment on this stock has really changed not too long ago if tesla came out and said we're going to reach 5

gene wilder?re? i kept thinking there must be a purpose to this somewhere, that a comedienne does, you know, roseanne roseannadanna and all this stupid stuff gets the most unfunny thing in the world. how am i going to get people to laugh about it, to be able to speak the words, to be able to not be afraid to be treated for it? the things you want to do. because when you're ready for what comes next, the only direction is forward. why go with anybody else? we know their rates are good, we know that they're always going to take care of us. it was an instant savings and i should have changed a long time ago. we're the tenney's and we're usaa members for life. call usaa to start saving on insurance today. and we're usaa members for life. ♪here you come again lookin' ♪a body has a right to ♪and shakin' me up so applebee's all you can eat is back. now with shrimp. now that's eatin' good in the neighborhood. ♪ >>> she said, you know something, my jokes are my only weapon against this. she said can you he

gene wilder? be a purpose to this somewhere, that a comedienne does, you know, roseanne roseannadanna and all this stupid stuff gets the most unfunny thing in the world. how am i going to get people to laugh about it, to be able to speak the words, to be able to not be afraid to be treated for it? iand automatically adjusts to keep you both comfortable. it's the final days of the lowest prices of the season. the queen sleep number 360 c4 smart bed is only $1299. ends sunday. hey, darryl. would you choose the network rated #1 in the nation by the experts, or the one awarded by the people? uh... correct! you don't have to choose, 'cause, uh... oh! (vo) switch to the network awarded by rootmetrics and j.d. power. buy the latest galaxy phones, get galaxy s9 free. but this hair color thing. i've got that figured out. garnier nutrisse. the #1 nourishing color crème, with avocado, olive and shea oils. nourishes while you color. for the rich color you expect. join the millions who have chosen nutrisse. no

>> so at that moment, gene became a very big movie star. ♪ gene was not a comedian.rica. >> i had been a fan of gene wilder's for many years, but the first time i saw him in person, i was hooked. it felt like my life went from black and white to technicolor. >> i could tell by the way she was talking about gene that it was something special, and it wasn't going to work out very well for g.e. after a little while, they split up, and she was with gene. >> it's wonderful to see the two of you here joining me together. >> it's wonderful to see us here too. >> seeing you. >> first appearance ever together? >> first one touching. >> first one with touching. where are you cutting this? >> gene and i lived together on and off for the next 2 1/2 years. my new career became getting him to marry me. being interested in sports was one of the things gene wanted in a woman. so i took tennis lessons in california. gene loved france, so i took lessons in french. [ speaking french ] >> i think i have always been searching for some kind of love that was perfect, and so of course it co

gene, what's your take on the quarter? >> melissa, my first reaction is i'm surprised that the guidance wasn't worse specifically they guided the high end of their guidance would suggest it's in line with the street keep in mind apple does not want to miss two quarters in a row so i thought that was an impressive positive the other earnings tha been coming in, the macro is impacting everyone and apple is doing a great job of navigating it that said, it was a miss another piece to this is the earnings was more powerful than i expected typically when companies miss their revenue, the earnings falls dramatically below plan. in fact they did deliver record earnings and so kind of putting this together, i think that explains kind of the reaction of the stock. one last more fundamental piece that jumped out at me was the services growth, margin growth in services year over year going from 58% to 62%. i think that's comforting for investors because they're putting a lot of weight in the services opportunity longer term. >> true.

gene wilder?kept thinking there must be a purpose to this somewhere, that a comedienne does, you know, roseanne roseannadanna and all this stupid stuff gets the most unfunny thing in the world. how am i going to get people to laugh about it, to be able to speak the words, to be able to not be afraid to be treated for it? >> she said, you know something, my jokes are my only weapon against this [ bleep ]. she said, zweibel, can you help me make cancer funny? i was starting a new show called it's garry shandling's show. and she was nervous at first about doing the show. we took a walk once, and she started to say, it's been six or seven years since i've been on tv. and i'm afraid that when i walk through the door, the studio audience isn't even going to remember me. >> oh, gilda. it's gilda radner, everybody. [ cheers and applause ] >> really, don't milk the applause like that. it's -- >> oh, i'm sorry, garry. i haven't been on television for a while. >> oh, what was wrong? >> i had cancer. what did

>> gene therapy is a one-time treatment. it's a different paradigm than typically seen in the pharmaceutical industry today. to ypical therapy can range more than $1 million per patient per year. >> trying toigure out how to capture that value, prices we typically hearn the order of about $1 million for a patient. >> $1 million drug might raise eyebrows and political backlash but to james addy, it's reasonable. >>s an insurance company, i would think it would be a good deal for them. >> and if it results in a better leaf fds his gr, it's hard to put a price on that. i'm meg tirrell. >> another look at the final day for 2018. the dow was up 265 points, the nasdaq added 50 and&p the 500 was up 21. but for the year, thedaverages tun their worst annual decade. quite a year. that will do it for us on report. business i'm sue herera. thank you so much for watching. happy new >> i'm bill griffin, we do look forward to seeing you in 2019. we leave you with a look at the new year's celrations aroun the globe the past 24 hours. happy

one negative effect of gene in the crops has been the reduction in seed strains. compared to one hundred years ago we should fear such loss of biodiversity to plant animal and human life if gene modification goes unchecked. it is for this reason that stephen hawking. intelligence is the ability to adapt to change we must not fear change we need to make you poor. thing here we have a sense of direction of civilization. inclusiveness. everybody's genius being important and we have to increase that. the powers that we use to attribute to accident or to god's. knowledge of the genome is reminiscent of the apple offered to adam many by this. for others the medic human future is the most natural evolution of all technology is an essential tool in mankind story but it is up to us to decide how you'll continue to assimilate it. that decision will affect not only our body but our universe as well what creates financing is the human you know this recreated money for example. religion god and god as we usually describe god is another contra ok so everything that you can name

to treat genetic disease by correcting gene mutation. possibilities for manipulating d.n.a. one negative effect of gene in the field. has been the reduction in seed strains. compared to one hundred years ago. diversity plant life if gene modification goes on. it is for this reason that. intelligence is the ability to adapt to change. change. direction of civilization. inclusive. everybody's genius being important and we have to just increase that as the powers that we use to attribute accident or to god's. knowledge of the genome is reminiscent of the apple offered money by the. human future is the most natural evolution of all technology is an essential tool in mankind. but it is up to us to decide how we will continue to assimilate it. that decision will affect. the body of our universe. experiencing is the. right religion. god as we usually describe god is another construct ok so everything that you can name is instructive of creation no you'd say this is both at once what we preach this is bored to construct a new creation what we do

diversity plant animal and human life if gene modification goes on. it is for this reason that stephen hawking. intelligence is the ability to adapt to change. change make it work. here we have a sense of direction of civilization. inclusiveness. everybody's genius being important and we have to just increase that as we gain the powers that we used to attribute accident or to god's. knowledge of the genome is reminiscent of the apple offered to me by the serpent for other. human future is the most natural evolution of all technology is an essential tool of mankind. but it is up to us to decide how it will continue to assimilate it. that decision will affect. the body. of our universe while. experiencing is the. recreated money for. religion. as we usually do. everything that. is. creation this is the creation. of creation. creation. is a construct whose. consciousness that i am is tied to the universal consciousness that you tap into that every. one day challenge darwinian. thoughts about evolution because darwinian evolution says random mutations and

would allow scientists to treat genetic causes of disease by correcting gene mutation. there are however less noble possibilities for manipulating d.n.a. when negative effect of gene in the feel ation on crops has been the reduction in seed strains not available to us compared to one hundred years ago. we should fear such a diversity plant animal and human life if gene modification goes on. it is for this reason that stephen hawking. intelligence is the ability to adapt to change. change make you poor. thing here is that we have a sense of direction of civilization. inclusiveness. everybody's genius being important and we have to just increase that as we gain the powers that we use to attribute accident or to god's. knowledge of the genome is reminiscent of the apple offered out of many by the serpent for others the medic human future is the most natural evolution of all technology is an essential tool in mankind story but it is up to us to decide how you'll continue to assimilate it . that decision will affect. the body of our universe. experiencing is the. recreated m

good genes. >> it's just your genes. >> you know, i do think i'm aging well, but i came from good genesld say about 40% of your aging is genetic and 60% is what you have done with your skin. if you are smoking, if you are laying out in the sun all the time, if you are very, very alcohol, you accelerate aging. >> i like a good night's sleep. i'm an eight-hour girl. >> well, sleep is very important. very important. i try to get to bed at a decent hour. i'm not a party girl. >> j-lo said she sleeps ten hours a night. and everybody knows when you sleep, you look better. the best position is to sleep on your back with your head slightly elevated. >> i say to my girls, don't go to sleep, you know, with makeup on. let your skin breathe when it can. >> yes, you should wash your face twice a day and sunscreen is a must, but come on. is there a beauty secret celebs are hiding? dr. beauty reveals one. >> the microgold facial. this is a model favorite. it's a microbotox, microfiller to give you an air brushed look. >> it's not the more the better, it's the micro the better. the difference between t

apple is going to miss this cycle, gene. isn't this an issue here >> they can miss it by several months i don't think they can miss it by a year. we're going to wait and see. having 5g phones, they need to give a little bit of clarity 5g doesn't have a ton of coverage in the u.s. i think that broadly we're thinking 2020, 2021 is when it ramps up it's not necessarily a competitive headwind this is a major upgrade. i'm not trying to look at the silver lining but what i'm trying to do is give it some perspective. china was bad. the upgrade extended -- or lack of subsidies that tim cook is talking about, that's nothing new. i was disappointed to hear tim talk about that because that's been going on for two years. i think the china thing is real. when he's talking about what's going on on social media, we chat related to huawei, that had a fractional impact on what's going on here -- >> to be clear, i'm sorry, gene, if you were still a sell side analyst and you were giving research out on this, you would have a strong buy on appl

gene: massive opportunity.lobally, collated $90 million sold a year, we are talking about -- they have 50% market share in the u.s. today. i'm not going to go through the technical details between electric and gas engines, but cars should be gas. it is pretty straightforward for a lot of reasons, so tesla's opportunity more specifically within that despite more competition is their ability to produce these cars at a more profitable pace than traditional oems. that will be the piece that separates this tesla story as an ev opportunity with its ability to produce a $40,000 mainstream vehicle. emily: what is the cash position of the company going into this year? dana: they have cash on hand. they need more of it. they need to pay this debt off. you need to raise capital at some point to build these other products that they have been clear they don't want to raise capital. there was nothing about capital needs and the release today. emily: so what does that mean? gene: i think if they don't get to the 360 mark, the

gene, this strategy that the u.s. continues to take that our economy is doing a lot better than their economy and their economy is getting slammed by the trade war, just how much leverage does that give the u.s. >> i don't think the u.s. has any particular leverage over china. as tim cook was just saying, i think we're in a world economy when either the u.s. or china sneez sneezes, it does give the other and the rest of the world a cold and so they both have a lot to lose i feel like the nature of our electoral system probably gives china more leverage. president trump really can't afford to start losing support among some of his republican senators from agriculture communities. he really can't afford to do things that look like they are risking leading us into a recession, which he knows would be very harmful not just for the economy, for his political prospects. but he also has a tough political challenge if he looks like he is just being too weak, because remember, this is a president who set the u.s./china trade d

they have to compete more on content. >> let's bring in gene munster gene, what did you make of the quarter and what is this change in how they report subs? >> so i haven't got through the detail on the mechanics of the change, but the net of this is they beat the sub number by 15%. the initial take was they slightly missed it but they actually did exceed it that's an important part is they're continuing to add subs the bigger questions related to the call tonight, i think somewhat related to tim's question too, but just around the pricing and separately the content spend, i was in los angeles yesterday and met with a couple of executives from the industry that are working closely with apple and separately netflix and amazon, all the players. they talked about the content spend is effectively going to double for doing these productions, this original content in the next two years. i think those type of elements need to be teased out in the call. >> okay. what are some of the other remaining questions that you have, gene, about this quarter what is striking to me and we were discussing this

it's a gene therapy. so he was born missing some genes on his retina, the back of his eye. ando with one shot this new drug is delivered into the eye, replaces the genes that he's missing and i was able to play video games withit that ltle boy who doctors sldd wou probably be blind by about 20, completely blind. his mom said he usedo fall down stairs occasionally, bump inton things w he was unfamiliar with an area. he now plays on a basketball team. really just an incredible thing it's the first fda approved gene therapy in the trco he was the first patient to get the surgery back in march and he's doing great. >> well, that is remarkable. t the price tag, $850,000 for both eyes is -- how does the company defend th? >> yeah, that's the sticker shock a lot of people have. and i sat downith the ceo and asked him some of those tough questions, how do they come up with that price. and they said they looked at what vision is worth. and that's sort of how they came up with this price of $850,000. the company hasn't been profitable yet. they're developing me gene therapies for the

the team wants to pinpoint the exact genes and biological workings that keep people thin.y want to target them in new weight loss strategies. but for now, there is no way to change the cards you've been dealt so the advice is to eat a healthy diet, gets plenty of exercise. for more on that story, charlie stayt and naga munchetty will be speaking to the report's lead researcher at cambridge university, professor sadaf fa rooqi. plus, they'll also speak to rachel murray, who's had a gastric band fitted. that's breakfast coming at 6 o'clock. this is the briefing from bbc news. the latest headlines: venezuela closes its embassy in the united states as nicolas maduro accuses donald trump of trying to overthrow him. 10 million per cent inflation. in business briefing, we're looking at the scale of the economic crisis facing venezuela as the stand—off between the government and opposition continues. protests have taken place in athens as the greek parliament votes on whether to accept the name of its neighbour as the republic of north macedonia. now it's time to look at stories m

so they've inherited genes that allow them to stay thin and also we know there are genes that increasettle bit more. when you say you found that, do you mean you ask them is your mum or dad thin, were your grandparents spend, where is the science beyond just looking at who came before, what have you discovered within their own bodies, as it were? the main thing is not asking them questions, it's looking at their dna. we had sample some 2010 people, 2000 very heavy people, 10,000 people who work normal weight. and it was looking at several hundred thousand genes across the entire gene known in those three different groups that we actually proved i looking at the genetics, that actually, the genetic score is very high in obese people, is that a medium stage in normal weight people and is very low in thin people. professor, the next question, if i may come off what can you do with that information. could you, is there some way that you could create people who cannot get fat? not quite like that! this research is important for two reasons, it may help us by pinpointing the actual genes and

it is the most common gene disorder in the uk.exeter medical school, scientists have discovered that those faulty genes are causing serious health problems, such as diabetes, liver damage and severe arthritis in far more people than previously thought. it was thought to be fewer than one in 100 people with the faulty genes. but the research suggests it is one in five men and one in ten women. it is very difficult to spot. the arthritis looks very like osteoarthritis and the diabetes is the same as other diabetes. so it tends to be only diagnosed quite late on when a lot of damage is done and treatment is only partially successful. so what we really are hoping that the nhs looks at ways of routinely testing for it. geese ' levels are ~ 7 should have been. ifound out they should have been. ifound out by accident. what i think would be goodis by accident. what i think would be good is there are more things tested for when you have a routine blood test. it is something that has been there for some time and could have gone undetected.

ron klain and gene robinson will join us next with what happens now. [cell phone rings] where are you? well the squirrels are back in the attic. mom? your dad won't call an exterminator... can i call you back, mom? he says it's personal this time.. if you're a mom, you call at the worst possible time. it's what you do. if you want to save fifteen percent or more on car insurance, you switch to geico. it's what you do. where are you? it's very loud there. are you taking a zumba class? carla is living with metastatic breast cancer, which is breast cancer that has spread to other parts of her body. she's also taking prescription ibrance with an aromatase inhibitor, which is for postmenopausal women with hormone receptor-positive her2- metastatic breast cancer as the first hormonal based therapy. ibrance plus letrozole was significantly more effective at delaying disease progression versus letrozole. patients taking ibrance can develop low white blood cell counts, which may cause serious infections that can lead to death. before taking ibrance, tell your d

the tribe that works togetherle and cooperates will pass on it's genes. the one on that reads earn ram l be whipped out. because of the programming there are certain things that can trick us into being part of the unity. thelo greatca thing about it isn is very good about this. that unity is not the problem. it's a good thing. isob tribalism is a good thing. it's finding healthy attachments and outlets for it. family,s friends, local communities. those are all good sports teams. politics can'ts, sever that very well at a national level without becoming distorting and tribal. that's the problem. government cannot love you. >> is identity politics which is the fourth mentioned is that another wordd for these three things? >> they are all important manifestations of this underline phaenomenon. identity politics is an ancient understanding or way of looking at the world. aristocat meant rule of the best, most worthy. another part said i want to play fafavorites with my genes coalition. niptism is hard wired. the aristocats invented the concept of noble blood.

>> well, i guess i have good genes -- [laughter] because somebody said the other day no president should have to go -- judge: that's right. >> -- through what you're going through, mr. president. because i'm going through all of this nonsense, it's all nonsense, but i have to be careful because these are dirty players. they're no good. and you've got the mueller

mean" gene okerlund.is some of his work. >> intercontinental champion of the world, randy "macho man." >> nothing means nothing. >> what do you mean by that? >> i'm talking all the way at the top. but the cream rise to the top. oh, yeah. macho madness. yes, got more -- than president jackson thinks that i got. >> unbelievable. right there. don't -- unbelievable things happen. >> i could be. >> here's when it goes. winning the belt from you is going to be easier than -- hold this. taking candy away from a baby. >> i'm ready for a -- i'm ready for a beer and a bratwurst, what about it? >> no way, when we're done, maybe. but not now. >> hulk, what in the world are you doing here at this hour of the day? it's only 6:00. give me a break! >> hey, it's time to train, daddy. time to train. come on geno. up, geno. come on, geno, all the way to the top. eye of the hulkster. >> that is hilarious. >> i remember watching wrestling as a kid. >> yeah? >> and certainly, you know, seeing him. while the wrestlers, you know

ron klain and gene robinson will join us next with what happens now. [birds chirping]

ron klain and gene robinson will join us next with what happens now. [birds chirping] accidents can happen anytime that's why geico is here 24 hours a day everyday. geico, fifteen minutes could save you 15% or more on car insurance. carla is living with metastatic breast cancer, which is breast cancer that has spread to other parts of her body. she's also taking prescription ibrance with an aromatase inhibitor, which is for postmenopausal women with hormone receptor-positive her2- metastatic breast cancer as the first hormonal based therapy. ibrance plus letrozole was significantly more effective at delaying disease progression versus letrozole. patients taking ibrance can develop low white blood cell counts, which may cause serious infections that can lead to death. before taking ibrance, tell your doctor if you have fever, chills, or other signs of infection, liver or kidney problems, are pregnant, breastfeeding, or plan to become pregnant. common side effects include low red blood cell and low platelet counts, infections, tiredness, nausea, sore mou

nicknamed mean gene okerlund held his hone beside some of wrestling's biggest personalities.nce mcmahon tweeting, it was impossible not to crack a smile room. r mean gene okerlund >>> and daryl dragon, one-half of the musical duo the captain and tennille, has died. he teamed up with his then wife toni tennille for 70s hits like love will keep us together andnc rescue after a woman became trapped in a car overturned in a watery ditch in florida. nbc's kerryrs hde her harrowing 911 call. >> reporter: a moment of crisis. >> there's water getting in the car, and i can't get out. >> reporter: 20-year-old amanda antonio on the phone. her car flipped over in a watery ditch. >> i'm freezing. >> okay. how deep of water are you in? >> well, now it's up to my chest. >> reporter: fearful her 911 call might end at any moment. >> i'm so >> reporter: her getting deeper. >> it's getting deeper? >> .location. >> is someone >> they're gettingealizes they may not reach her in time. >> i can't kick the i can look my google maps. >> reporter: she gives that information to the operator. >> hello!

paul, gene, thank you. >> thank you. says it will stop selling all location data from mobile phones to brokers. this comes a report that companies are selling data to shadowy organizations without customer knowledge. other carriers and at&t pledged to stop selling data to brokers but made some exceptions. the exceptions will stop in march. >>> pentagon is preparing options in case the president trump declares a national emergency to build a border wall but can legally get away with that? >> new york city mayor de blasio has quite a week saying that he will take from the rich to pay for it. our panel weighs in on that next. ♪ val, vern... i'm off to college and i'm not gonna be around... i'm worried about my parents' retirement. oh, don't worry. voya helps them to and through retirement... ...dealing with today's expenses... ...like college... ...while helping plan, invest and protect for the future. so they'll be okay... without me? um... and when we knock out this wall... imagine the closet space. yes! oh hey, son. yeah

dependent on single gene abnormalities.ow that we are able to easily sequence dna they want to harness it this isn't the kind of thing that can happen overnight. we are getting to the point where dna sequences is good enough in the hands of a little company like loxo, it might not have gone anywhere. but in the hands of eli lilly, it could be blown out worldwide. can you image a shanghai hospital, if you have a gene for a lung cancer, loxo could be a lifesaver. initially eli lilly took a hit loxo's technology is visionary and now belongs to lilly and the stock went higher because of it. for a long time when we thought of pharma, we thought of drugs for the same old remedies. sales forces that pushed product. but that is no longer the case that is what is so exciting about being out here take novartis, a doctor, got a master degree of public policy from harvard and happens to be an actual scientist. this guy is reinventing it maybe solutions, i do. many of which could be turned out to be blockbusters that produce billions of

a surprising number of kids found with health risks hidden in their genes. doctors looking for hearing loss to heart disease and cancer. >> a family calling it a christmas miracle after a boy was found facedown in the pool on christmas day. >> he's not responding! >> the emotional reunion with the heroes who helped save him. >> announcer: this is nbc nightly news with lester holt. >>> good evening. it's a new playing field in washington politics tonight with new faces, but a familiar arena. democrats led by new house speaker, nancy pelosi, officially now the majority in the house of representatives. 116th congress, the most diverse ever with more than 100 women. pelosi's leadership being tied for second time as speaker immediately tested by the partial government shut down and a president staring her down in a high stakes showdown over the border wall. our hallie jackson has the latest. >> congratulations, madam speaker. >> today belongs to her. >> i now call the house to order on behalf of all of america's children. >> but nancy pelosi's second speakership

a surprising number of kids found with health risks hidden in their genes. doctors looking from everything from hearing lose to heart di ase and cancer. >>> a family calling it a christmas miracle after a little boy was found face down in a pool. tonight the emotional reunion with the heroes who helped save him. >> announcer: this is "nbc nightly news" lt with lester ho >>> good evening, everyone. it's a new playing field in washington ceolitics tonight with new but a familiar arena. democrs led by new house speaker nancy pelosi officially now the majority in the house of representatives. the 116th congress, the most diverse ever with more than 100 women. her second time as speaker immediately government shutdown and a president staring her down at a high stakes showdown over the border wall.ha ouie jackson has the latest. r.> congratulations spea >> i now call the house to order on behalf of all of america's children. >> reporter: but nancy losi's second speakership may be by it him, a new pical universe as a triumphaelosi and her party take over the house.

your kids' dna found a surprising number who seemed health i but had hidden health risks in their genes. >> the women's basketball team does something they haven't in 26 games. >> this little boy who defied all odds to survive falling into a pool. "early today" starts right now. >> good morning. i'm marlie hall. >> so great being with you on this friday. i'm frances rivera. the shutdown showdown enters week two. today president trump will meet with top congressional leaders at the white house as they try to hammer out a deal to reopen the government. but as of now, neither side is budging and with democrats retaking control of the house, there is no telling how long the partial shutdown could last. nbc's tracie potts joins us with the latest from d.c. reopen the government last hat . >> reporter: it went nowhere because republicans on the other side are calling it a political stunt. they won't even consider it, even though they interestingly passed something on a temporary basis last fall. but now they say without any money for the wall, the president won't sign it. so they will not con

so what if a individual takes that $2.1 million gene therapy and then in one years gone, is now under a blue cross plan or different insurance plan. how exactly then are the costsr uped? i like that they're thinking outside of the box. let's do an annuity type model. but i thinkbl that pro more work and more creative ideas need to come to the ay >> what about the second part of that that sue mentioned. essentiall they're saying if the drug doesn't work, we don't get paid. what do you think of that and do you think other drug makers are likely to try and adopt that? >> absolutely. so the latter part of it is a value-base type arrangement where exactly what you said, if it doesn't work, you don't pay. e medicare program is trying to do tomt withof the therapies, and i think that's absolutely a step in the right rection. i will also mention that the trade groups, pharma and bio, they r ally favor value-based payment system. so i thenk for products that are coming down the pike with seven figures, something is loing to have to be done. otherwise it w bankrupt our system. >> now, this type

he said he manipulated their genes to make them unable to get hiv. >>> manny pacquiao is having a rough homecoming after celebrating his win in las vegas. >> police say burglars broke in and ransacked the boxer's los angeles home. take a look. police taped off the block last night as nearly a dozen officers showed up to investigate. it happened lesshours after 40-year-old manny pacquiao defeated adrian groner. police are investigating and you better hope manny doesn't find you first. >>> kpix5 news at 6:00 begins right now with ken bastida and juliette goodrich. >> now at 6:00 a rising star in washington now diving into a presidential run, the road ahead for kamala harris. >> san jose drivers prepare for delays, a look at efforts to extend b.a.r.t. through the south bay and the impact on commuters. >> and a bay area surfer paralyzed at a popular surfing hotspot shares his story right where it all happened. kpix5 news at 6:00 starts right now. >>> good evening. i'm ken bastida. >> and i'm juliette goodrich. we start with a major announcement from senator kamala harris. she has officially

fight against isis some of the fighting right now is going on in some but in most districts like a gene the right of the border between syria and iraq and of course if. turkey is maintaining that it will cut out on all fronts of against what squatting terrorist elements in syria either way without me in them a talking the forces who are currently engaged in the fight against i saw him talking about that as the fighters will cut his men mainly cut it so it is going to be even more complicated from here on in. in other world news at least fifteen people have been killed after a military plane crashed in iran it happened near five airport just west of the capital tehran iranian state television says severe weather may have played a role the plane had been attempting to make an emergency landing. the u.s. secretary of state has been meeting a saudi arabia's leadership in riyadh on the latest leg of his tour of the middle east mike on bail has held talks with saudi arabia's crown prince but he's canceled his leg of the his trip to the middle east to return to the u.s. for family funeral pale

because it's an evolved gene it's a gene that's already evolved to be stronger so we literally have super bugs that are getting stronger and stronger because we use more antibiotics good wardrobes good thank you all right. get out of our show for you today remember everyone in this world we are told will love them up so i know you all. rolled into the down time people are watching those parks and it was great to. see it. go jump. in as a two town terriers and it was. time to say scott you know facebook should rename itself as space crime because they are assisting in. baby this move toward totalitarianism and the question i guess is why why now why the child's right ism rearing its ugly head in america at this time of the. us veterans who come back from war often tell the same stories. were going after the people who were killing civilians they were not interested in the wellbeing of their own soldiers either there already several generations of them so i just got this memo from the circulated branch offices we're going to attack and destroy the government in seven countries in five years

is doing pretty well. >> well, there's another conversation gene, we'll get you into studio. gene, cow founder of sen directors, ran the campaign or a huge part of it to take the government to task to give parliament a better vote you got what you wanted, and now look at the mess good to see you again. >> thank you >> good point. steve, thank you very much for that reaction from europe, would you believe? e.u. brexit negotiator nicole barnier said -- speaking to the european parliament, he said it's up to the u.k. government to reveal what it wants to do next, but the irish backstop must be a part of any brexit agreement. >> translator: a brexit will remain an absolute priority in the weeks to come. however, at this time no scenario can be ruled out. it's particularly true the scenario we've always wanted to avoid. that of a no deal. today ten weeks out the risk of a no deal has never been higher. >> let's talk about mr. macron as well. the french president emmanuel macron has also been quick to weigh in, saying the disarray needs to be resolved >> translator: the british gov

who says he created the world's first gene- edited babies... is likely to face criminal charges. that geneticist... he jankui ... has already taken criticism >>> a man in china that said he created the world's first gene edited baby will likely face criminal charges and the genetic test he jiankui spoke at a conference in hong kong last fall about manipulating the dna of the embryos to make them immune to the hiv. chinese investigators are out with the preliminary findings and say that he and his team seriously violated state regulations by editing embryos and implanting them into the female volunteers. he is accused of using unsafe methods and forging materials. chinese said that he violated the explicit law banning embryo editing and did so "in pursuit of personal fame and fortune, self raised funds and deliberate invasion of supervision of recruitment of personnel. they say that one volunteer gave birth to twin girls with the genetic implant. one bay area expert caused unconscionable but warns not to use him, he jiankui, as this scapegoat. >> what he did was unconscionable and

nicknamed mean gene held his own. he was 76. >>> also tonight, actor bob einstein, the funny man from "curb your enthusiasm" died at 76. he was known for his character super dave and made so many laugh over the years with his own show and late night appearances. >>> just ahead tonight, her car overturned in water but hear how one woman was able to lead rescuers to her just in time. >>> how a streaming thriller became one of the most talked about movies of the year. >>> the super fan who inspired a legion of sports fanatics. >>> next tonight the dramatic rescue after a woman was trapped in a car overturned in a watery ditch in california. florida. kerry sanders with the 911 call. >> reporter: a moment of crisis. >> there is water getting in the car and i can't get out. >> reporter: 20-year-old amanda antonio on the phone, her car flipped over in a watery ditch. >> i'm freezing. >> okay, how deep of water are you in? >> well, now it's up to my chest. >> reporter: fearful, her 911 call might end at any moment. >> i'm so

there is so much great science there is so much possibilities in cell and gene therapies in our coreeline. we can't use our capital across all of the different areas we're in what we're doing with alcon is a spin, the tax neutral spin, to our shareholders say, shareholder, look, you get to own alcon, which is a leading medical devices company, leading in its space, great company with a great outlook. you have the opportunity now to own that great leading company and own novartis, which is a compelling thing >> it's really important because that is science. you're willing to lose the surgical part too. >> well, what we're really looking for is places where there's true synergies in the group. when i look at medical devices in contact lenses, clearly huge opportunity to address blindness, but it doesn't fit with our core innovative medicines model. that's why it makes sense to let alcon be free to really develop itself as a stand-alone company. >> cigna's acquisition of express skriptcripts was a major takeover m&a in the industry passes on cost savings to both clients and shareholders