and that it might be genetic and. like his mother a white or studied medicine but he didn't remember how warning until some of his own patients who had the disease reminded him. quite a began to go for regular checkups and for many years everything was fine when examining doctors found no sign of a disease he felt relieved and assumed he didn't have any unusual genetic risk but then he was diagnosed with colon cancer. when i was 43 i had a colonoscopy and they found i had cancer of the cold on them. they were able to remove it surgically so i didn't need came a therapy humor to appear. at that point whiter decided he wanted to know whether his disease had a genetic component. he wondered if he might have passed the risk on to his own 4 children. doctor turned a patient went to munich center of medical genetics he wanted to know if he carried a genetic variation associated with increased risk of colon cancer. many experts say that it's a wise choice to make in situations like his. there are a whole range of genetic dis

genetic tests going to far reaching consequences so before you do a genetic test get informed what it really means and talk to your. some diseases can actually be caused by genes take colon cancer or breast cancer for example some special forms can be inherited it's simple blood test can tell you if you're affected. and i go to is a retired physician for a long time he didn't know that he has an unusually high risk of getting a certain kind of cancer. it's a genetic risk he was born with. only 21st minamata when i was 20 my mother died of metal started colon cancer. while she was in hospital she warned my sister and me that we might get it too. and that it might be genetic and if you didn't gain an illegal. like his mother the writer studied medicine but he didn't remember her warning until some of his own patients who had the disease reminded him. of the vital began to go for regular checkups and for many years everything was fine when examining doctors found no sign of a disease he felt relieved and assumed he didn't have any unusual genetic risk but then he was diagnosed with colon

doctor turned patient went to munich center of medical genetics he wanted to know if he carried a genetic variation associated with increased risk of colon cancer. many experts say that it's a wise choice to make in situations like his. there are a whole range of genetic diseases where it makes sense to identify the risks for example hereditary cancer syndrome so familiar with these that can manifest in adults especially with regards to cancers genetic testing allows you to estimate the risk of developing a disease and in which quite accurately then a screening plan can be developed for the family. tests look for mutations in specific genes in cells taken from a sample of blood. from mutations are ones that are known to be associated with specific diseases. another kind of genetic testing is gaining in popularity you just send in a saliva sample to a commercial provider many companies advertise the service online they claim to be able to detect increased risk for over $200.00 diseases all for a low price but unlike in targeted genetic testing most of these commercial providers don't searc

what are the differences in their genetics?ferences in the genes related to their immune response? are there differences in their underlying health? so, it is a uniquely rich set of data, and i think we could go very quickly into getting some very, very important discoveries. scientists are looking for tiny variations in patients' genetic material. they will be examining genes like the ones involved in making a structure on the outside of cells in ourairways. it acts as a docking site for the virus, allowing it to enter and infect the cell. it could be that differences in people's dna changes this, making it easier for the virus to lock on, resulting in a more severe illness. and we are not at the peak, yet. intensive care units are filling up. and some patients are younger, with no underlying health issues. they're now the focus of a new study starting in new york. for diseases like flu and herpes, some people carry genetic variations that make them seriously ill, and this could be the case with coronavirus. it was discovered

why do you suspect that this could be genetic? well, this is exactly the problem that we try to tackle, as you just said. previously healthy children, adolescents or adults arbitrarily under the age of 50, who suddenly are critically ill. so, the hypothesis that we're testing with helen hsu at the national institutes of health, is that these patients carry genetic variations -- in the past, people would say mutations -- genetic variations that are silent clinically until they're infected by the coronavirus. and in a few days or weeks, they develop severe luminitis and have to be into an intensive care unit. >> so it's basically something in their dna that enables the virus to be much more lethal in how it acts? >> right, exactly. but you know, this is not an idea that came out of the blue. helen hsu at the nih had discovered mutations, variations, responsible for luminitis caused by the rhinovirus. and we had discovered other variations responsible for influenza numonitis, so we had already shown for two other types of viral that

and that genetics revolution is intersecting the growing virus crisis. if you have these pandemics in the past we never been able to sequence the viral genome or guess the digital readout to understand the virus. we never have computer models to allow us to test different responses. we've never been able to develop testing despite the monumental screwup in this country. now we watch as viral genome you today as it spreads around the world. and for tracking it. and those who are also on this call will bring together the bio from around the world to say are there genetic patterns we can use to understand what kind of people may be prone to increased resistance to viral infection or maybe at greatest risk to make smart decisions around that kind of knowledge. or with a vaccine. saying maybe we can do it in a year. some say two years. was talking to a very senior scientist in los angeles the other day. and he said he didn't know if we ever could achieve it. george is the scientist of the possible. and then all things surveillance system. all of these tools a

inside is genetic material from half a million volunteers donated.y have followed the help for more than a decade and will track those with covid-19. >> we are looking at the data to understand the differences between those individuals. differences in genetics, are there differences in the genes related tommuno responses or underlying health? it is a uniqueltarich set of nd i think we could go very quickly into getting very important discoveries. rebecca: scientistr are looking ny variations in genetic material. they are examining genes like one that is involved in making a structure on the outside of cells in our airways that acts as a docking site for theus v allowing it to enter and infect the cells. it could be that diflerences in p's dna makes it easier forto the viruock on, resulting in more severe illness. intensive care units are filling up and some patients are younger with no underlying health conditions. they are the focus of a n study starting in new york. for diseases like flu and herpes, some people carry genetic riations that make them

and what we're seeing is an intersection of the genetics revolution and all the tools of the genetics revolution and this crisis so let me say a few words about each of that. the first, the genetics revolution. among the billions of species that live and have ever lived , our one species suddenly has this ability to read, write and hack the codes of life and it's incredible and we think of it. just one species and it's almost a godlike power. these are the powers we've imagined our god's having through our recorded history and it suddenly are starting to have those powers but spiderman or spiderman's uncle, with that power comes responsibility and there comes a responsibility to make sure that our most cherished ethics and values are guiding that most powerful technology and that's what my book and this whole conversation is about. so the gen x revolution is racing forward and i focus on three primary areas. one is in this transition from our world of generalized to precision and then predicted healthcare health and life. humans, we are a map massive negative data set but we are not a

genetic screening burden. next w. it's like a creature from another planet it's revolutionary not only by appearance it's also a technological. the citoyenne d.s. and under god goddess it's still revealed by killers fans from all over the world. and float away. in 60 minutes on. the global corona crisis you can find more information online at c.w. dot com and on t.w. social media channels. welcome to any good shape coming up on the show. better sleep tricks to help combat insomnia. abnormal fat deposits the suffering caused by jima. and genetic testing how well can a d.n.a. analysis predict your disease risk. and here's your host dr constantly go tot kitschy.

genetic screening. next on d w. it's like a creature from another planet it's revolutionary not only by appearance it's also a technological marvel the citoyenne d.s. and under god goddess it's still reviewed by killers fans all over the world. and float away. in 60 minutes on. the global corona crisis you can find more information online at e.w. dot com and. social media channel. welcome to shape coming up on the show. better sleep tricks to help combat insomnia. abnormal fat deposits the suffering caused by the. end.

but we know its genetic code. this code is like a blueprint.re lifting parts of it and combining it with existing viruses to create something that looks like the coronavirus. the idea is this can then be given to animals or humans. others are injecting the raw code straight into test subjects. when researchers think they've found something that works, it has to be tested again and again and again, and go through so many clinical trials to make sure it's effective and that there are no unintended side effects. even after that, you have to make this vaccine on a massive scale and deliver and distribute it to people all over the world. as muslims celebrate the holy month of ramadan, some muslims are expressing concern that the official advice about social distancing isn't reaching many in the community. our religion editor, martin bashir, has been speaking to one gp in greater manchester in england to hear her views about fasting, faith and whether public health messages are getting through. with afternoon surgery over, dr siema iqbal is on the sc

make up past research has shown that genetics do have an influence on the course of viral infections and scientists are looking at some key genes very closely in the covert 19 pandemic especially the ones that include 4 and control the expression of an enzyme in the cell membrane called ace 2 it's what the corona virus uses as a gateway to get into the cell could variations there or make some people more susceptible than others may be it's pretty unlikely though that there will be a single genetic variant that determines whether you get a mild or severe a case of covert 19 the 1st wide scale research studies in the area are ramping up now but they'll take time to carry out and evaluate. and if you have a question for us about the virus simply post it in the comments section of r.t.w. your chat and that wraps up today's edition of coven $1000.00 special for more on the event i make to check out our social media channels and our website that's d.w. dot com which has dedicated covered 9000 pages in 30 languages i'm chris caldwell and thanks for watching and before we let you go many sci

in january, researchers published the genetic code of coronavirus.s a close match to a disease found in horseshoe backs in western china. they fly and roost in huge numbers, so easily spread disease. at the level of the virus in their bodyis at the level of the virus in their body is low, which is why something like this, the pangolin, or another animal may have caused and passed on to humans. if the got -- virus has entered into an immediate hose, it's quite likely to change in some way which may enable it to be easierfor it to infect a human being. how then what that virus spread to wuhan, a huge city of about 11 million people? the first subset was this place, on animal market. the first 41 hospital patients and would bond, 28 had a connection to this place. we think the evidence is pretty compelling that an animal in that market was infected with this virus and unfortunately, some of that virus spread into humans quite rapidly, quite efficiently. is not clear—cut. even though there is evidence that animal market spread the disease, 13 of those fi

basic is a genetic code of c. sing in there and then some kind of proteins develop multiply and that triggers it in one immune response this is not the completely new vaccine but it's hasn't been used really for vaccine against coronaviruses in the past it was something developed for cancer research so for fighting cancer and therefore it's not really clear how it's going to go it's one of 4 big scene sets a company biome take is going is having in the pipeline right now and is also going to. be running through the process was a polish institute and of course it's only one of many vaccines that different pharma pharmaceutical companies are. developing right now on different medical platforms f.i.b. said of course it's not clear yet the how it's going to work because we have to wait for clinical trials to be conducted but how promising is this vaccine how confident is the company and what they've created. as the company is fairly confident that one of the 4 vaccines that they have in the pipeline will work. as a po

rebecca: scientists are looking for tiny variations in genetic material.y are examining genes like one that is involved in making a structure on the outside of lls in our airways that acts as a docking site for the virus, allowing it to enter and infect the cells. it could be that differences in people's dna makest easier for the virus to lock on, resulting in more severe iness. intensive care unitsre filling up and some patients are younger with no underlying health conditions.th are the focus of a new study starting in new yorkas. for di like flu and herpes, some people carry genetic riations that make them seriously ill and tha could be the case. >> it was discovered that there are inborn areas of immunity that render huma beings specifically vulnerable to one crobe and this can be latent for decades until infection by that particular group. sohat our program does is essentially testing whether this idea also applies to covid. rebecca: the rapid spread means there is no shortage of patits to study. it is hoped the work could identify those most at risk

one of the differences is in their genetics.re differences in their underlying health? so it is a uniquely rich set of data, and i think we could go very quickly into getting some very, very important discoveries. scientists are looking for tiny variations in patients' genetic material. they will be examining genes like the ones involved in making a structure on the outside of cells in our airways. it acts as a docking site for the virus, allowing it and infect the cell. it could be the differences in people's dna changes this, making it easier for the virus to lock on, resulting in a more severe illness. and we are not at the peak, yet. intensive care units are filling up. and some patients are younger, with no underlying health issues. they are now the focus of a new study starting in new york. for diseases like flu and herpes, some people carry genetic variations that make them seriously ill, and this could be the case with coronavirus. it was discovered by our group, and other groups that there were surprisingly inborn areas

raceis because of some genetic inference.eal, it leads to constructive differences between us, i'io constructive differences between us, no genetic differences because of race, it is because of inequality. african—americans are more likely to be living in poor accommodation with well—paid work be living in poor accommodation with well— paid work and be living in poor accommodation with well—paid work and not being able to access health care as easily. it really is exposing globally and in america as well... ijust really is exposing globally and in america as well... i just want to give sam a word on this. the daily express will focus on british news but is the american angle something your paper is covering? we are looking at the global situation not just america. i think this ap article if people get a chance to walk on and have a look at it is really fascinating because it invokes around the world round up of the situation and also it has some. . . the situation and also it has some... it tells the tale of how many people a

information and i can see that both genetic materials are now with and have. us. now going to provide the genetic information by inserting just one cell into the egg and that one cell is enough to provide all genetic information to give rise to the entire organism. when. he. will. come to life go through. 'd his will version. and when it's crying. ok. both of them i learned that. someday we can get. off the list and. i believe. we have to ok then you tell your thing you got the information all of. our own you know. how. how are you are you are. you. but he wrote the. business to me. that it's. through the she's the. in the. when would be a family center and go. look up the you know my is a science scam not a 1000000 years old at the time robinson young i not been to my brains and it seems encouraging me. and the. oldest soul. all to you that there is told. me they would be. my calling of purpose to see me on the floor may have few of those ya all saw how the public and. why if you say no i mean that's defeat my new fees i'm right all of us me i totally voted f

you should not have access to this information whereas i say that people are already getting this genetic testing again and whether it's for prenatal reasons or if you're thinking about getting married i know a lot of people for example in certain genetic populations will get tested for tay-sachs disease so people are already doing this through i think these geneticists are saying we're going to why don't you do it before hardock want you do it way earlier on in the process well a friend here in washington was cyber chatting up someone on our time dot com when she said she had worked in the bush administration he assumed w. when she showed up at the restaurant it was clear she had worked for george h.w. humans can use old photos to fill a book d.n.a. doesn't lie does it. it does not and so a lot of people will be getting surprises with these apps we've seen now where they get surprises with new family members that they didn't expect but there is also something now where they're going to get surprises and you can be related to a match i mean think about that you could have shared to see em

information and i can see that both genetic materials are now within have. us. now going to provide the genetic information by inserting just one cell into the egg and that one cell is enough to provide all genetic information to give rise to the entire organism. when. he. will. come to live oh you. will lose. and when it's crying. ok. both of them over and then. someday we can get. off the land and. i believe. we have to. their you talk a thing you got the one probation a war. zone you know. how. how are you. if you. can where she did it. i didn't know that. but in this to me. i relate. that it's so this is. the lady's kemble she threw that she spent the. day the. in the cash. when would be a family affair and of the moment but then you know my is a science scam not a 1000000 years old at the time robinson young i not been to my brains and he encouraged me. and the. older soul. saw all to you that there is still. a pedestal and they would be. my calling of purpose to see me on the throne nephew of moshiach all over me. why if you do you say no i mean that's

enough to provide all genetic information to give rise to the entire organism. when. he. will come to life go through. with the version. and when it's crying. ok. both of them knowing that. someday we can get a call on the. coffin lid. i believe. we have to. ok then you tell your thing you got the one can always you know all of . our law you know. how. how are you are you are. if you. wrote that. business to me. i laid. him bullshit through the. in the cash. when would be a family's there and the bottom of the you know my is a science scam not a 1000000 years old at the time robinson young i do not believe in my praise and he encouraged me. and the. oldest soul. all to you that there is still. a pedestal today would be. my calling of purpose to see me on the floor of nephew of moshiach all over me. why if you think you know you're not i mean i see my new fees i'm right all of us i totally voted for you we didn't know you from america. more quickly go through this is the headquarters of p.t. on. it's just this week everyone stays here and it's very convenient for

here's a tricky one genetics is it possible that the d.n.a. in our bodies makes us more or less out to be able to do with this so this is an interesting question that scientists are starting to examine a new study out of kings college of london which has not been peer reviewed yet is actually really interesting they are saying that genetic factors explained about 50 percent of the differences between people symptoms of coven 1000 so of course there's the question why are some people asymptomatic why are some people having really strong symptoms blah blah blah they actually did a study on a bunch of different twins and they found that this could account for about 50 percent but again this study hasn't been peer reviewed yet but if true it could be very interesting now of race also comes into question we're asked we're talking about disease and genetics right for example code 1000 is killing black americans at disproportionately high rates right answer in chicago 70 percent of the people who died were black despite the fact that 29 percent of ch

can a genetic test help you stay healthy. some diseases can actually be caused by genes a simple blood. do you know what's hidden in your d.n.a. . genetic screening. and good. 30 minutes on d w. in a timeless way discover the. stars make on the w. . we know that this is very time for the coronavirus is changing the world changing our lives so please take care of yourself good systems wash your hands if you can't stay at how we're d.w.b. for here for you we are working tirelessly to keep you informed on all of our platforms we're all in this to get on together make it. stay safe everybody. is serious a mistake save a priest face it. says .

we will be experiencing genetics outside the realm of healthcare. it's gonna get much bigger and it's can have tougher and more challenging issues. and then perhaps the most profound application will be how these technologies change not just the way we make babies and we will shift towards more of that. but also, it will change ultimately over time the nature of the babies we make. this is a very profound conversation. it is a conversation about science. but ultimately this is a conversation about ethics because all technologies none of them come with their own built-in value system. into the most significant application of those technologies. since the hardcover came out last april. i have a preliminary reference. since then we know that there are at least three we just don't know. and then the world health world health organization created that's international advisory community. i was chosen as one of the members. it tries to suggest at least what might be a framework for that. and how we can apply the very powerful technologies in a way that max

can a genetic test help you stay healthy. some diseases can actually be a gene the simple blood tell you. do you know what's hidden in your d.n.a. . genetic screening burden. in 60 minutes on d w. story so that people will go for the information they provide. the means they want to express g.w. on facebook and twitter up to date in touch follow us. this was a global operation that it was not authorized to the know what happened to the remains that was the question of the how is that possible we don't have a history of good things are sort of 16 months of go by since a saudi journalist jamal khashoggi was killed by agents of his own state is dumbo but the issue doesn't go away my guess this week here at the munich security conference is idle algebra the saudi minister of state for foreign affairs why are there still so many unanswered questions about the murder and why the massive.

can a genetic test help you stay healthy. some diseases can actually be. a simple blood test and tell you. do you know what's hidden in your d.n.a. . genetic screening. good should. be in 60 minutes on d w. the sustainable way to scope the bauhaus. starts my own w. . how does a virus spread. why do we panic and when we'll all miss. just 3 of the topics covered in a weekly radio show is called spectrum if you would like and new information on the crown of virus or any other science topic you should really check out our podcast you can get it wherever you get your podcast you can also find us at g.w. dot com look for inside science. etc my name's melody don't stand this is free stuff abolish. it.

then there's the question of genetics is it possible that because of my particular d.n.a. because of the chemistry that i was born with i will be more apt to beat this thing or less up will i be among the 25 to 50 percent who gets this disease but never even knew that they had the disease. all right i've got a couple of things i want to show you let's talk about age real quick. look at age is a factor not the only factor but it is a consistent determinant so i want to take you through 2 different studies the 1st is from the c.d.c. . look at the shows 31 percent of all cases 45 percent of all hospitalizations 53 percent of all i see you admissions and 80 percent of the deaths associated with covert my team are older than 6580 percent of the deaths older than 65 by the way i got a cavity out here this data and here's what they're this stuff gets tricky this data it's only been compiled with information from february to march that's not a long time of data collection i want to comes to scientific studies right 2nd study let's go to the china study there it is all right this i

currently, there is no way because no genetic data have been generated.mme is precisely to in role individuals younger than 50, previously healthy, someone younger than 50, previously healthy, someone who, a month later would be integrated with covid—19, sequence the genome worldwide and try to identify genetic variations. currently, there is no answer, but inafew currently, there is no answer, but in a few months, unfortunately, perhaps a few years, we may have an answer. we are doing the best we can. thinking so much forjoining us. “— can. thinking so much forjoining us. —— thank you. now away from coronavirus — 15 prominent members of hong kong's democracy movement have been arrested for organising illegal protests last year in what's being seen as a fresh attack on anti—government activists. britain has expressed its concern over the arrests, calling the right to peaceful protest fundamental to hong kong's way of life. earlier this week beijing's most senior official in the city called for a new security law to deal with dissent. david campanale has m

what are the differences in their genetics?rich set of data, and i think we could go very quickly into getting some very, very important discoveries. scientists are looking for tiny variations in patients' genetic material. they'll be examining genes like one that's involved in making a structure on the outside of cells in ourairways. it acts as a docking site for the virus, allowing it to enter and infect the cell. they'll be examining genes like one that's involved in making a structure on the outside of cells in ourairways. it acts as a docking site for the virus, allowing it to enter and infect the cell. it could be that differences in people's dna change this, making it easier for the virus to lock on, resulting in a more severe illness. and we're not at the peak yet... intensive care units are filling up, and some patients are younger with no underlying health conditions. they're now the focus of a new study starting in new york. for diseases like flu and herpes, some people carry genetic variations that make them serious

there's some wonderful scientists who have worked on the genetics, the molecular genetics of the viruses precursors to hiv, the viruses in chimps and monkeys and the genetic diversity of hiv one group and from of the pandemic hiv scientists have managed to locate of the spillover event with a high degree of confidence, there's a certain provision audi in science both high degree of confidence, they located to southeastern, one chimpanzee and one human, then he cut himself on the hand, blood to blood contact while butchering the chimp for food and in the early part of the 20th century, sometime around or before 1908. michael and beatrice are the scientists who have done that work. so there are these diseases, the spillover they are zoonotic. another technical term i want to familiarize you with, reservoir host. it is the kind of animal in which the bug from a virus or whatever it is, lived permanently in think is truly without causing disease. without causing mayhem in a particular creature. why does it look better probably because it's been in the disease for millions of years. an accomm

asia and the other 2 are most commonly found in europe and the us now those 3 types have different genetic signatures which means that their genomes have mutated in ways that allow us to track how the virus has spread around the globe but that doesn't mean that the genetic changes have have altered these 3 variants to have different effects on you when you catch them at least there's no clear evidence of that so far. does recovering from one variants protect you from the other variants. what you're asking is basically how much does the virus have to change before a trained immune system won't recognize it if someone gets reinfected and once again why we don't really know every day we're learning more and more about how the immune system reacts to this particular pathogen but at the same time it's a valving we just have to hope that eventually we'll pull ahead in the race. can you use boiling water is a harmless disinfectant to kill the virus on surfaces in the bathroom or kitchen. the w.h.o. does say that heating water to temperatures above 65 degrees celsius has been shown to kill related

this fire is genetically modified to be used as a biological weapon and this was one of those conspiracy theories that was bound to pop up in the midst of a global pandemic right i mean there's been too many books and movies with that as a plot line but the team of researchers that studied the genetic makeup of the virus recently published some compelling arguments for why it wasn't engineered but must have naturally evolved 1st they said source code to most closely resembles coronaviruses found in bats that don't cause disease in humans and of course and evil scientists trying to build a superbug would have started with one that's already been proven to make a sick 2nd in our computer models the changes to the stars code to genetic sequence that allowed it to start infecting us just don't look like they should work very well they aren't mutations that any bio engineer would have chosen if they were trying to build a superbug because the models would have said they don't really work so no the coronavirus was not designed by humans. can supplements like fish oil zinc ovitz and then that's