the genetic engineering of trees is following on the tradition of genetically engineering crops and many of the same traits that are being engineered and the trees are things that have been done in crops since about the eighty's. and so, yeah, it's, it's all, it's all done in a lab and it involves various techniques for inserting. in the case of the american chestnut, inserting jeans from a completely unrelated speech, sees a grass barley into into the genetically engineered, excuse me, into the america, chose not to create that genetically engineered americans just not so very, very process of genetic modification is very disruptive to the genome, so they're going in there and they're using either a bacterium in this case, or in some cases literally did a coded little bullet. so if they fire into the cell, and they hope that it land somewhere useful in the, in the genome on the, in the, excuse me, i'm one of the chromosomes so that they can then have a product that can be tested out, but can be replicated that could be eventually put out into the field. so in the case of the g, just not

the genetic engineering of trees is following on the tradition of genetically engineering crops and many of the same traits that are being engineered and the trees are things that have been done in crops since about the eighty's. and so, yeah, it's, it's all, it's all done in a lab and it involves various techniques for inserting. in the case of the american chestnut, inserting jeans from a completely unrelated speech, sees a grass barley into into the genetically engineered, excuse me, into the america, chose not to create that genetically engineered americans just not so very, very process of genetic modification is very disruptive to the genome, so they're going in there and they're using either a bacterium in this case, or in some cases literally did a coded little bullet. so if they fire into the cell, and they hope that it land somewhere useful in the, in the genome on the, in the, excuse me, i'm one of the chromosomes so that they can then have a product that can be tested out, but can be replicated that could be eventually put out into the field. so in the case of the g. e chests

the genetic engineering of trees is following on the tradition of genetically engineering crops and many of the same traits that are being engineered and the trees are things that have been done in crops since about the eighty's. and so, yeah, it's, it's all, it's all done in a lab and it involves various techniques for inserting. in the case of the american chestnut, inserting jeans from a completely unrelated speech, sees a grass barley into into the genetically engineered, excuse me, into the america, chose not to create that genetically engineered americans just not so very, very process of genetic modification is very disruptive to the genome, so they're going in there and they're using either a bacterium in this case, or in some cases literally did a coded little bullet. so if they fire into the cell, and they hope that it land somewhere useful in the, in the genome on the, in the, excuse me, i'm one of the chromosomes so that they can then have a product that can be tested out, but can be replicated that could be eventually put out into the field. so in the case of the gene, just

and somatic and inherited genetics must be clearly imagined, that is cancer is always genetics, but not necessarily inherited genetics. well, and non-inherited, that is why the disease can manifest itself at 4 years and at 7 years, because it is a random process, it is a random process, but it is not accidental that, for example, the peak incidence of acute lycosis in children occurs at 4 years, the fact is, the fact is that our immune system, the first years of a person's life are a period of such formation of the immune system, yes, when the body's immune system encounters all ... the diversity of the surrounding world from the point of view of microbes, bacteria, viruses, fungal infections, from the point of view of food, from the point of view of just any such chemical molecular environment, and the immune system during this period develops very rapidly, in the development of the immune system there is such a very important stage when the genes encoding antibodies, they are rebuilt very intensively, that is, literally at the dna level, cuts occur and ... these small breaks in th

you can see that the basic insurances support genetic tests for very few cases and a wide range of geneticit is not covered by basic insurances , unfortunately, supplementary insurances may cover it according to the type of contract, but a large part of the society does not have supplementary insurance, and this may require that, god willing, the authorities support basic insurances that a large part of the population has. in our country , workers are covered by insurance in the field of employment let's hope they include the genetic discussions , how much does it cost? see , the most expensive genetic test is around 20 million, and the most basic test is about one and a half to two million in the department such as royan as a it is a non-governmental public institution, its definition is almost half of the private definition, that is, 50% is the private definition , including this 50%, it is approximately up to this limit, and it should be said that for families who need a test, if the insurance support is weak, they are sometimes deprived. from the test and god forbid, they will face som

we'd only want to identify in genetic variance that cause genetic disorders that manifest in early childhood food and keep this out of money fist in. and we aim to identify diseases where early screening or treatment could significantly improve outcomes or even lead to a tourist or the computer to kind of get and can. so any diagnosis made through screening must have a direct impact on treatment. while this seems reasonable, that also means withholding diagnoses that could still be important to families to take the romero family 7 year old tiara has a rare genetic disorder cone do 15 q syndrome. children born with this condition can have a range of complex disabilities including autism. spectrum disorder and epilepsy. amen. 6 more mountain park there. she was 6 months old when she had her 1st seizure and we went to the hospital, but they missed diagnosed it as a re fox and sent us home safely, things escalated quickly after that were done and i had some kids aside. she was having a 1000 seizures a day, and we went through a long and difficult journey to finally get a diagnosis. you know sick

arc genetics based on ancient dna. a specialist for the united states military at fort detrick once told me ancient dna is dna that's not walking. so it really does bring us down to the present day plays a very important part in the american military for identifying missing were particular really thrilled that today's presentation is able to occur in black history month of 2024. we hope that this brings special joy to all of you to see the kind of work that the size of the human past is able to do today on this wonderful occasion, i myself, as many of you know, have a background in economic history. and so i'm familiar with the the first stages of the total industrial revolution in new england with in which water power and then steam power were harnessed to machines and largely young women were harnessed to the machines to produce the textiles. and it's only through this project that i learned that in the 18th century, in many in some parts of america, human power was also harnessed to those machines, but not through w

it's very clear about me on the sweet only want to identifying genetic variance that cause genetic disorders that manifest in early childhood food and keep this out of money 1st bid. and we aim to identify diseases where early screening or treatment could significantly improve outcomes or even lead to a tour come to that kind of. and so any diagnosis made through screening must have a direct impact on treatment. while this seems reasonable, that also means withholding diagnoses that could still be important to families. take the romero family 7 year old kiara has a rare genetic disorder called do 15 q syndrome. children born with this condition can have a range of complex disabilities including autism, spectrum disorder, and epilepsy. m. it's 6 more, not in park there. she was 6 months old when she had her 1st seizure and a new team. we went to the hospital, but they missed diagnosed it as a re fox and sent us home safely. things major step for our health care system is inputs this team on file. so believe we have the right to know if i should be fully the right. not to know certain things,

the genetics of the country has been seen in the 7th program. yes , the 7th program has been seen well, there is another point, please stay healthy , mr. mirzaei, thank you very much for your presence in hello reporter. be with us, dear viewers, until we see the sports part of today's program together. let's go to alachiq. hello reporter, mr. baglo. hello , good morning. mr. hosseini. good morning to you . in the name of allah, the most merciful, the most polite and respectful service to you, dear and respected viewers. the two delayed games that have been very noisy in the last few days and today the tractor teams are going to play. sepahan will face each other in tabriz. in particular , i will discuss the same issue with my colleague morteza eizdpanah . hello, good morning. what's up? good morning. well , you mentioned that we have a game overdue, tractor sepahan, which is also a very important game. it has been delayed since the 16th week. in their championship course, they are trying, their ranks are actually very important, third and fourth

t-therapy is modified, genetically modified t-lymphocytes that are taken from a person, genetically modified changes, they become more aggressive, they are returned to the person, these lymphocytes are somewhat modified and they kill the lymphoma cell. we already have sightings of several years, that patients for whom, in general , there was no chance, in general, to live for several months, are still living with... in remission and we, in general, are the second center in the cis countries where this is done now. we also have a medical genetic counseling center, the only place in the country where not only patients, but also relatives of patients, if they suspect that they have some kind of hereditary predisposition, they can get advice on this topic, they will be advised passing a certain testing, and accordingly what they should do then, and this... communication is not with a biologist, communication with a doctor who not only understands the test results, but can also somehow indicate the clinical significance for this particular person, this is an hour and a half . i have been working

the suspected golden state killer was exposed by genetic genealogy.ott's case, in a legal precedent, the genetic genealogy evidence was presented to a jury and helped put him behind bars. this is a game-changer for investigators, for forensic scientists, for prosecutors. genetic genealogy is the best crime-fighting tool that's come along since dna came along. moore: in jay and tanya's case, genetic genealogy was able to develop a suspect who had never even been considered previously.

people are even afraid, and genetics, there are genetically modified products, and genetic developmentsmehow debunk this myth. we must begin with the fact that genetics, by and large, is a science that actually studies , which evaluates, in fact, the entire potential of a living organism, from viruses to humans. when i was at school, well, it’s clear that we studied genetics only partially as a branch of biology, and some still believe that studying genetics at such an advanced level, well , it’s still early in school, because the science is too complex, on the other hand, this is the cutting edge, is that how you feel about it? you know, if you ask the question, is it worth eliminating genetics? high-quality textbooks and if this is implemented, then it seems to me that it will increase prestige, and people will treat themselves more correctly with each other. what culture does not have a fairy tale in which the main character cooks a cough or soup from an ax, a stone, well, in general, whatever comes to hand, our scientists with with the help of unusual additives, they hope to turn or

our most ambitious task is to build the genetic history of the peoples living on the territory of russiaelizaveta rozhdestvenskikh puts on protective clothing to work in a sterile laboratory; such serious equipment is necessary to exclude the influence of external factors on the research results. we turn out to be such snowmen. elizabeth a geneticist at sirius university studies ancient dna, which can be several hundred thousand years old. not a single speck of modern dust should fall on unique materials. it is a well-known fact that dust is mostly human epithelial cells. and just like that, it just might fly off at some point. from your face, or with a stream of air, also fly out of the nasal cavity, like this... these are biologists, these are historians, these are archaeologists, anthropologists and this whole large scientific community, it makes a contribution, at least bit by bit, but he contributes. using ancient dna, scientists can trace the history of individual peoples and all of humanity, for example, find out what our ancestors ate and drank, and restore their appearance, hair

today we will talk about genetic diseases, about oncology, especially genetic ones. diseases of children sciences, professor, director of the institute of experimental and molecular medicine, center for pediatric hematology named after dima rogachev. hello, mikhail. hello, konstantin. we have statistics, they are as follows: every year in russia approximately 3,500, from 3,500 to 400 patients become ill with cancer. a you mean hematological and pediatric , these are all tumors, these are all tumors, all of all pediatric oncology is 3,500 patients, 3,700 to be precise, but our area of ​​interest also includes patients with hereditary blood diseases and hereditary diseases of the immune system, then what called hereditary immunodeficiencies, but these are diseases in which the immune system stops working as a result of some kind of breakdown - at the genome level, and the breakdown is most often inherited, that is, this is the total number of patients every year, who are part of the area of ​​interest, the center, the area of ​​our competence, is about 5-600 people, at what age can the deb

humanity as genetics, well, man, he will remain with his genetics, because this is a species, homo sapiensnd if its genetics changes fundamentally somehow, it will be a different species, it will no longer be a person, which of the two new species will defeat homo sapiens 2.0, so let’s call it so, or homo sapiens? 2:0 we will remain, whoever wins, and of course there will be competition, of course there will be competition for everything, we understand you, thank you very much, we talked about what our future will be like... today at 17:50 on the russia channel, and then in winter and summer in different colors, summer residents are complaining, coniferous plants are withering, why the reason and how to bring them back to life, we will tell you in a few minutes, please, acquaintance and roll call, you can build without it, i am very glad that you came to visit me, how much tea did you drink, how much? i still give up with joy, let’s all wave our hands when everyone is at home with timur kizyakov, on sunday on rtr. let's finally let's get acquainted. christina, your younger sister, what abo

and in 2015, i contacted the institute of genetics, russian academy of sciences, they took samples ofng... archaeological expeditions in different parts russian federation and in the south in the north and in the west and in the east, they bring a large amount of archaeological material, this gives us the opportunity, as they say, to immediately analyze these monuments in order to trace various important things, including for archaeologists, these objects from the oglakhty burial ground, it... is located on the territory of modern khakassia, not far from the capital of the republic, the city of abakan. the ancient archaeological site was discovered in 1902, and a year later the first excavations began, and here on the table are just some of those very early finds: the right leg of a teenager, samples were also taken from him to understand what age it is, whether it is a girl or a boy, in addition, here... and braids are also presented, but we do not know whether this is the same person or not, or two different people , just genetic studies can tell us whether this person is the same o

years ago , no one really believed in the possibility of creating artificial tissue organs through genetic editing, but today this is already... clinical practice, at the same time, at the same time , new infections that appear that we did not yet know, the need for access to new drugs, and the need for gentle treatment for the patient are serious challenges that give a big impetus to the development of medical technologies, i am certainly impressed, today you mentioned the exhibition you were at before plenary session, i am also impressed by the level and scale of developments in russian science, which is not at all behind the world, we really have something to be proud of, a huge, huge number of reasons to be proud, and i am honestly impressed, of course , by the speed, speed, like the speed of the emergence of new diseases, infections, and the speed of response of medical science, fundamental and applied, the speed of victory over diseases, so... today, if you allow, we would like to talk at the plenary discussion about new technologies that are developing medical science, about the peo

your grandfather, it seems, experienced a mutation, a genetic mutation. my father. so, he was born in 1927. william shakespeare — unfortunate name. and his father, geoffrey, who was a junior minister in the liberal government the last time the liberals were in coalition — was very worried about it and was very upset about it because suddenly his child was short. the reason i mention the grandfather first because isn't it the case that it was the grandfather's genetic mutation which he was not aware of? that is right. which he then passed on to your father, his son? exactly, you are quite right, stephen, sorry. in fact, 60% of people who are born with my condition are born to average height parents. anybody who watches this programme who is themselves average height or even tall could have a short child. obviously, myself, i have a 50—50 chance of a short child and, indeed, my father had an average height child and a fully affected child — me. but in average people, it is very rare. maybei in 20,000. sperm — it's usually sperm — go different and, therefore, an achond

they don't have my genetic mutation potentially.d lives, and we can do something about that. were there societal pressures on you not to have children? yes. yes, there were. and i remember when — my daughter's name is ivy — when her mother was pregnant, there was an expectation, they showed that that pregnancy was affected by achondroplasia. and i think there was an expectation — she was born in 1988 — there was an expectation we do the right thing and have a termination. and we went, "yeah?" you mean an expectation from the medical professionals around you? yes. notjust medical professionals. friends, colleagues thought that it was the right thing to do. what about your own parents? well, my father was very welcoming. he was a doctor. he was... he knew the genetics, but he also knew that it need make no difference. and so was my mother. i mean, she's been a fantastic great—grandmother to my grandchild. but for her, maybe it was more questionable because she didn't have it. she didn't have the condition. my father did, so he knew it

aging is controlled by biological processes and genetic factors of a particular individual.ion stem cell depletion. a person is born with information, a genome, embedded in him. the human genome contains up to 30,000 genes. cells are constantly dividing. during the division process , errors occur that accumulate during dna replication. cellular senescence occurs when a cell stops. divides and reduces its activity. senescent cells are present at all stages of human life. with age, their number increases, causing their heterogeneity. the ability of cells to divide is limited. it is regulated by telomeres which are protected by dna. the reduction of telomeres can be compared to a time bomb, which is activated as soon as... old age, oh, but i would like to add to the discussion about what aging is, because now we are mainly talking about individuals again, about all these cells are all business, there is also the concept of population aging, when the proportion of elderly people is growing, growing, this is now observed in all developed countries, twenty to 30% of the population

should we screen all human embryos for genetic abnormalities? should we root out mutations? could we be sleepwalking into a new era of eugenics? my guest is the ethicist, disability rights activist and writer tom shakespeare, who also happens to live with a genetic condition, achondroplasia, which has restricted his growth. should we embrace difference rather than use science to root it out? tom shakespeare, welcome to hardtalk. thank you, it's great to be here. it's great to have you. now, in your personal life and your professional life, everything has been intertwined in terms of your campaigning work, your academic work. ijust wonder whether you ever, for a moment, considered going into something entirely disconnected from your own personal circumstances? something like accountancy, law, geology? you know what, there are short people, restricted growth people in all of those professions. there are farmers, teachers, solicitors, everything. but i did not go that way. so as a social scientist, i've always been interested in what others experience and so obviously disabilit

crucial, important genetic test. and i do wanna make sure that that is clear that the test itself is lifesaving, very important. somewhere along the way, certain states and their departments of public health decided that they could start storing these through regulation. it wasn't law, at least not in california. and so the head of, in our case, the california department of public health wrote into regulation the ability for this biobank to be created, for them to start storing these samples, and there's also a funding mechanism, right? the researchers then pay to get those samples, which self-funds this biobank. so it was created through regulation, not through law. it didn't go through the lawmaker process. they're now working on that, trying to sort of write this into law. at least that's my understanding of some of the amendments going into this latest bill. but yeah, it was created through regulation by the heads of these public health departments. - yeah, and as you mentioned, i mean, it's done so much good ove

the research team in the you k, genetically manipulated the tomatoes with tiny genetics is, is cool, chris, but cats 9. you can see here in the future while we grow up the wall top tomato, which is not just as motto. and so our basement, each motto in parallel to the call really is how the difference within is that good thing is in tomato we didn't see any of and you loss or bruce defects for those. so i just as most clothes and it just takes like tomatoes to make these tomatoes, the scientists fuse the domestic scissors and change them. only 2 of the tomatoes already have private men. d 3, a close relative victim. indeed. prove it. 20 is actually a building block, a victim. indeed. over to men, d 3 to be exact. that's what our body needs. normally an enzyme called a worker in the tomato yourselves, would use the private to men's d to produce another molecule collateral. but the genetics is stopped the enzyme in its tracks. that means business as usual for private. mindy 3 permits men. d 3 cannot be used to build victim. indeed. ready when privates and then the 3 is hit by the sun's

k. genetically manipulated the tomatoes with tiny genetic scissors. cool, crisp a cus 9. you can see here in the future while we grow up, the waltz motto, which is not just as small so and so our basement, the tomato in parallel to the call really is how the difference within is that good thing is in tomato we didn't see any of you loss or uh, gross defects for those editors most of calls. and it just takes like tomatoes to make these tomatoes, the scientists fuse. the gymnastics is, has been changed to monte 2 of the tomatoes already have pivots. mindy 3, a close relative victim. indeed. pivots. wendy is actually a building block, a victim indeed. over to me in the 3 to be exact. that's what up what he needs normally an enzyme, blue color work through in the tomato yourselves. what do you use to prove it to me in the, to produce another molecule collateral but the genetics is stopped the enzyme in its tracks. that means business as usual for previous mindy. 3, perfect. mindy 3 can not be used to build victim. indeed. ready when private some and the 3 is hit by the sun's

k. genetically manipulated the tomatoes with tiny genetic scissors cool, crisp across 9. you can see here in a few trial week row of the waltz motto, which is now just as motto, and so our basements, each motto in parallel to the call really is how that differs. within is that good thing is in tomato we didn't see any you loss or growth defects for those. so i, this is most of clause and it just takes like tomatoes to make these tomatoes, the scientist fuse the domestic scissors and inch the money. tools at tomatoes already have prove it to me in d. 3, a close relative victim. indeed. prove it. 20 is actually a building block, a victim indeed. all victim, indeed 3 to be exact. that's what up what he needs. normally an enzyme, the blue color will occur in the tomato yourselves. what do you use to prove it to me in the to produce another molecule collateral but the genetic says is stop the enzyme in its tracks. that means business as usual for prey, richmond, d. 3 permits, men. d 3 cannot be used to build victim indeed. or. ready when private some and the 3 is hit by the su

diseases, imagine, 20 years ago, well 30 years ago , about 60 inherited genetic diseases were known,cell anemia, thalasemia, hemophilia, everyone knows tsarevich alexei, now their number is being calculated, but it has not yet reached 1000, but already more than 6,000 for sure, this is a condition that was possible to identify by studying, reading the dna of people who obviously had this disease, that is, these people went there for some reason, they, for example, in there were some cases in the family, well, some cases, yes, which geneticists could track down, but could not find out the cause, now this is done in general as easy as pie, it is enough to take, say, parents, grandparents and children who have or do not have manifestations of such and such a disease in this family, and having read their dna, simply compare to make such, well, a fairly simple association, are there any characteristic changes, those very... countries, in china and so on and so forth in russia in public databases at best stored, well, in accessible databases, if we are not talking about private people who

material and men for their genetic material.ildren that come part, we can to ensure they have a good life. with somethingike egg andisconte genetic material when it leaves. rsome states don't have laws for protecting eggs and sperm from being used in research later on. help a family and i need, but it could be used in genetic research that could beliefs you have. you may have seen the recent wall street story about the man who has over 200 dr and counting because he has bdo sperm for many years. for a long time he thought about it as a way to make extra mo he. one day one of the children who had his■)perm, who was his son, reached out to him. it clicked. these are my children. they aren't just my sperm. just someone else's kids. these are my kids. he has the same color hair. shhamy smile. that one looks like my mother. it overcame s seknow all 200 of. reaching out to every famie can find. because, he wants to know the children who hcom.he wants to b. i think ihe h tught of that on the front end, he may havethe fertility industry

a random process, well, some kind of tragedy of errors, but, probably, a variety of errors at the geneticevel lead, well, to the development, for example, leukemia and so on , that is, after all, if the patient has you turned out to be, if parents brought a child to you, how do you find out where it happened, and what is important? do you even know what happened to him, or are you just doing your medical part, this is very important, because, well, firstly, there are dozens, in fact more than a hundred different variants of genetic damage, which are one disease, one disease, one disease acute lycosis, but these mechanisms, yes, genetic causes, types of breakdowns, dozens of them exist, they greatly influence... there are breakdowns that make the cell completely insensitive, and such lycosis cannot be cured with conventional chemotherapy, there are breakdowns in which the sensitivity is super high, such patients have a 98% chance of fully recovering and returning to normal life, that is, how do you know, how do you determine where the obligatory occurred, a mandatory analysis at the start

but in general, where genetics, yes, is still most applicable.le to imagine a single area, well, probably, except for some kind of machine tool industry, where genetics did not play a completely decisive role. now the role of genetics is the same. agriculture is very high, now there are conversations not just about selection, it is when we learned to read genetic information that we have the possibility of so-called marker-specific selection, in fact we know that a species carrying such markers will have some advantages there, this is a disadvantage, and accordingly we are already taking specific representatives, crossing them and leading them in a directed manner. this also applies to animals, this also applies to plants. at what level is russia from the point of view? world-class genetic research, and in a number of cases absolutely first-class developments are actually obtained there ; in particular, this is precisely possible with the development of genetic technologies, primarily genomic editing, and this is now a new medicine, what we say i

material and men for their genetic material.t is important to ensure that the children that come from us, even in part, we do the best we can to ensure they have a good life. with something like egg and his sperm donation you have no control of what happens to the genetic material when it leaves. some states don't have laws for protecting eggs and sperm from being used in research later on. you thought you were donating to help a family and i need, but it could be used in genetic research that could violate beliefs you have. you may have seen the recent wall street journal story about the man who has over 200 children and counting because he has been donating sperm for many years. for a long time he thought about it as a way to make extra money and help women in need. one day one of the children who had his sperm, who was his son, reached out to him. it clicked. these are my children. they aren't just my sperm. they are just someone else's kids. these are my kids. i can see my eyes in that kid. he has the same color hair. she ha

the cost of genetic testing and genetic sequencing has fallen dramatically. there are no barriers to innovation with new, clinically relevant biomarkers. new biomarkers are being recognized on a routine basis. pera would permit the position of natural phenomena -- the privatization of natural phenomena such as those embodied by genetic -- pera which shut the door. a new patent covering newly discovered biomarkers would appear and impede patient access to such basic information. because so many are engaged in identification of new biomarkers, a diverse group of new tutees stand in the way of clinicians efforts to conduct analysis of a patient's genetic information because state-of-the-art testing would require permission from all of them. none of them would be required to grant such permission. that was the reigning set of conditions before the decisions. pera would take us back, back to a time when the total charge for access to biomarkers in just the two brca genes was $4400. today, a test with more information cost a fraction of that amount. the patent syst

providing counseling services and genetic diagnosis in the first comprehensive genetics center of the central university jihad, which was opened on the occasion of the 4th anniversary of the formation of the university jihad. we are witnessing a new work in the country that has done a new work , which is a source of pride inside and outside the country in the field of various genetic , molecular and cellular diagnostics. in fact , they are conducting various tests now, either on the blood samples of the people who refer or an attempt has been made to diagnose genetic diseases in this center using the world's latest technologies and advanced equipment on the sample of the water sac around the fetus. chromosome 21 is 3, which means that this child is a seed syndrome child who is in the mother's womb in the 15th week. yes, we took the sample and it was determined that this is a seed syndrome or it may have a missing chromosome okay, there is a girl who has one missing chromosome , turner says that it won't be difficult now, but at least you know that in the future, she will have infertil